Stimulation of calcium efflux from rat liver mitochondria by adenosine 3′5′ cyclic monophosphate
The uptake or release of Ca2+ from rat liver mitochondria was studied by means of a sensitive Ca-electrode. It was found that using palmitoyl coenzyme A together with carnitine and ATP as substrates that Ca2+ was released gradually from mitochondria by adenosine 3'5' cyclic monophosphate....
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
1980
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| Online Access: | http://psasir.upm.edu.my/id/eprint/39753/ http://psasir.upm.edu.my/id/eprint/39753/1/16.%20Stimulation%20of%20calcium%20efflux%20from%20rat%20liver%20mitochondria%20by%20adenosine.pdf |
| Summary: | The uptake or release of Ca2+ from rat liver mitochondria was studied by means of a sensitive Ca-electrode. It was found that using palmitoyl coenzyme A together with carnitine and ATP as substrates that Ca2+ was released gradually from mitochondria by adenosine 3'5' cyclic monophosphate. The effect was obtained with either mitochondria preloaded with Ca2+ or with their physiological content of Ca2+. No such release was obtained with the usual substrates used to provide energy for Ca2+ uptake by mitochondria. |
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