Recent advances in electrochemical and optical sensing of dopamine
Nowadays, several neurological disorders and neurocrine tumours are associated with dopamine (DA) concentrations in various biological fluids. Highly accurate and ultrasensitive detection of DA levels in different biological samples in real-time can change and improve the quality of a patient’s life...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI
2020
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| Online Access: | http://psasir.upm.edu.my/id/eprint/38150/ http://psasir.upm.edu.my/id/eprint/38150/1/38150.pdf |
| _version_ | 1848848798988632064 |
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| author | Eddin, Faten Bashar Kamal Yap, Wing Fen |
| author_facet | Eddin, Faten Bashar Kamal Yap, Wing Fen |
| author_sort | Eddin, Faten Bashar Kamal |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Nowadays, several neurological disorders and neurocrine tumours are associated with dopamine (DA) concentrations in various biological fluids. Highly accurate and ultrasensitive detection of DA levels in different biological samples in real-time can change and improve the quality of a patient’s life in addition to reducing the treatment cost. Therefore, the design and development of diagnostic tool for in vivo and in vitro monitoring of DA is of considerable clinical and pharmacological importance. In recent decades, a large number of techniques have been established for DA detection, including chromatography coupled to mass spectrometry, spectroscopic approaches, and electrochemical (EC) methods. These methods are effective, but most of them still have some drawbacks such as consuming time, effort, and money. Added to that, sometimes they need complex procedures to obtain good sensitivity and suffer from low selectivity due to interference from other biological species such as uric acid (UA) and ascorbic acid (AA). Advanced materials can offer remarkable opportunities to overcome drawbacks in conventional DA sensors. This review aims to explain challenges related to DA detection using different techniques, and to summarize and highlight recent advancements in materials used and approaches applied for several sensor surface modification for the monitoring of DA. Also, it focuses on the analytical features of the EC and optical-based sensing techniques available. |
| first_indexed | 2025-11-15T09:40:14Z |
| format | Article |
| id | upm-38150 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:40:14Z |
| publishDate | 2020 |
| publisher | MDPI |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-381502020-05-03T22:59:17Z http://psasir.upm.edu.my/id/eprint/38150/ Recent advances in electrochemical and optical sensing of dopamine Eddin, Faten Bashar Kamal Yap, Wing Fen Nowadays, several neurological disorders and neurocrine tumours are associated with dopamine (DA) concentrations in various biological fluids. Highly accurate and ultrasensitive detection of DA levels in different biological samples in real-time can change and improve the quality of a patient’s life in addition to reducing the treatment cost. Therefore, the design and development of diagnostic tool for in vivo and in vitro monitoring of DA is of considerable clinical and pharmacological importance. In recent decades, a large number of techniques have been established for DA detection, including chromatography coupled to mass spectrometry, spectroscopic approaches, and electrochemical (EC) methods. These methods are effective, but most of them still have some drawbacks such as consuming time, effort, and money. Added to that, sometimes they need complex procedures to obtain good sensitivity and suffer from low selectivity due to interference from other biological species such as uric acid (UA) and ascorbic acid (AA). Advanced materials can offer remarkable opportunities to overcome drawbacks in conventional DA sensors. This review aims to explain challenges related to DA detection using different techniques, and to summarize and highlight recent advancements in materials used and approaches applied for several sensor surface modification for the monitoring of DA. Also, it focuses on the analytical features of the EC and optical-based sensing techniques available. MDPI 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/38150/1/38150.pdf Eddin, Faten Bashar Kamal and Yap, Wing Fen (2020) Recent advances in electrochemical and optical sensing of dopamine. Sensors, 20 (4). art. no. 1039. pp. 1-47. ISSN 1424-8220 https://www.mdpi.com/1424-8220/20/4/1039 10.3390/s20041039 |
| spellingShingle | Eddin, Faten Bashar Kamal Yap, Wing Fen Recent advances in electrochemical and optical sensing of dopamine |
| title | Recent advances in electrochemical and optical sensing of dopamine |
| title_full | Recent advances in electrochemical and optical sensing of dopamine |
| title_fullStr | Recent advances in electrochemical and optical sensing of dopamine |
| title_full_unstemmed | Recent advances in electrochemical and optical sensing of dopamine |
| title_short | Recent advances in electrochemical and optical sensing of dopamine |
| title_sort | recent advances in electrochemical and optical sensing of dopamine |
| url | http://psasir.upm.edu.my/id/eprint/38150/ http://psasir.upm.edu.my/id/eprint/38150/ http://psasir.upm.edu.my/id/eprint/38150/ http://psasir.upm.edu.my/id/eprint/38150/1/38150.pdf |