N-ethyl-n-nitrosourea induced leukaemia in a mouse model through upregulation of vascular endothelial growth factor and evading apoptosis
Chemical carcinogens are commonly used to investigate the biology and prognoses of various cancers. This study investigated the mechanism of leukaemogenic effects of n-ethyl-n-nitrosourea (ENU) in a mouse model. A total of 14 3-week-old male Institute of Cancer Research (ICR)-mice were used for the...
| Main Authors: | Abdullahi, Aliyu, Shaari, Mohd Rosly, Ahmad Sayuti, Nurul Syahirah, Reduan, Mohd Farhan Hanif, Sithambaram, Shanmugavelu, Mohamed Mustapha, Noordin, Shaari, Khozirah, Hamzah, Hazilawati |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI
2020
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/38121/ http://psasir.upm.edu.my/id/eprint/38121/1/38121.pdf |
Similar Items
Histopathological features of peripheral T-cell lymphoma in Sprague Dawley rats induced with N-methyl-N-nitrosourea
by: Al-Salih, Hutheyfa A. H., et al.
Published: (2011)
by: Al-Salih, Hutheyfa A. H., et al.
Published: (2011)
Chemopreventive effects of garlic powder on N-methyl-N-nitrosourea-induced ductal mammary gland carcinoma in female Sprague Dawley rats
by: Al-Salih, Hutheyfa A. H., et al.
Published: (2015)
by: Al-Salih, Hutheyfa A. H., et al.
Published: (2015)
Alteration of serum biochemical parameters and urinalysis in Sprague Dawley rats administered with N-methyl-N-nitrosourea
by: Hakimi, M. K., et al.
Published: (2012)
by: Hakimi, M. K., et al.
Published: (2012)
Some chemical carcinogens for leukaemia induction and their animal models
by: Aliyu, Abdullahi, et al.
Published: (2019)
by: Aliyu, Abdullahi, et al.
Published: (2019)
Effects of Morinda citrifolia on early stage of leukaemia in rats
by: Hamzah, Hazilawati, et al.
Published: (2010)
by: Hamzah, Hazilawati, et al.
Published: (2010)
Chemopreventive and chemotherapeutic effects of garlic powder on n-methyl-n-nitrosourea (mnu)-induced lymphoma-leukaemia and mammary gland tumour in rats (Not for loan)
by: Salih, Hutheyfa Abd Alhussein Ali
Published: (2016)
by: Salih, Hutheyfa Abd Alhussein Ali
Published: (2016)
Effects of N-methyl-N-nitrosourea on seed germitantion of Stevia rebaudiana = Kesan N-Metil-N-Nitrosourea pada percambahan biji benih stevia rebaudiana
by: Ahmad, Lyena Watty Zuraine, et al.
Published: (2019)
by: Ahmad, Lyena Watty Zuraine, et al.
Published: (2019)
Effects of N-Methyl-N-Nitrosourea on seed germination of Stevia rebaudiana
by: Lyena Watty Zuraine Ahmad,, et al.
Published: (2019)
by: Lyena Watty Zuraine Ahmad,, et al.
Published: (2019)
Effects of N-methyl-N-nitrosourea on seed germination of Stevia rebaudiana
by: Ahmad, Lyena Watty Zuraine, et al.
Published: (2019)
by: Ahmad, Lyena Watty Zuraine, et al.
Published: (2019)
(N-Ethyl-N-phenyldithiocarbamato-KS)- triphenyltin(IV).
by: Mohamed Tahir, Mohamed Ibrahim, et al.
Published: (2012)
by: Mohamed Tahir, Mohamed Ibrahim, et al.
Published: (2012)
Evaluation of Curcuma longa L. on chronic leukaemia rats: serum biochemistry parameters and urinalysis
by: M. Y., Yusnaini, et al.
Published: (2012)
by: M. Y., Yusnaini, et al.
Published: (2012)
Carcinogenic effects of n-methyl-n-nitrosourea administered via oral and intraperitoneal routes in female sprague dawley rats
by: Mohd Kassim, Muhammad Hakimi
Published: (2014)
by: Mohd Kassim, Muhammad Hakimi
Published: (2014)
Di-n-butylbis(N-ethyl-N-phenyldithiocarbamato- kS)tin(IV).
by: Kamaludin, Nurul Farahana, et al.
Published: (2012)
by: Kamaludin, Nurul Farahana, et al.
Published: (2012)
Moringa oleifera hydorethanolic leaf extract induced acute and sub-acute hepato-nephrotoxicity in female ICR-mice
by: Aliyu, Abdullahi, et al.
Published: (2021)
by: Aliyu, Abdullahi, et al.
Published: (2021)
Effects of Morinda citrifolia on N-methyl N-nitrosourea-induced peripheral T cell non-Hodgkin's lymphoma in Sprague Dawley rats
by: Al-Salih, Hutheyfa A-H
Published: (2010)
by: Al-Salih, Hutheyfa A-H
Published: (2010)
Status of research on medicinal plants for livestock production in Malaysia
by: Sithambaram, Shanmugavelu, et al.
Published: (2012)
by: Sithambaram, Shanmugavelu, et al.
Published: (2012)
Potentiation of testicular cytotoxicity by the alkyltransferase inhibitor O6 benzylguanine and the 5-fluorouracil/N-(2-chloroethyl)-N-nitrosourea molecular combination, B.4152
by: Thompson, Michael J., et al.
Published: (1996)
by: Thompson, Michael J., et al.
Published: (1996)
A one-dimensional coordination polymer, catena-poly[[[[N-ethyl-N-(pyridin-4-ylmethyl)dithiocarbamato-κ2 S,S′]zinc(II)]-μ2-N-ethyl-N-(pyridin-4-ylmethyl)dithiocarbamato-κ3 S,S′:N] 4-methylpyridine hemisolvate]
by: Poplaukhin, Pavel, et al.
Published: (2017)
by: Poplaukhin, Pavel, et al.
Published: (2017)
Pre-eclampsia: the role of vascular endothelial growth factor and its interaction with the vascular endothelium
by: Brockelsby, Jeremy Charles
Published: (2001)
by: Brockelsby, Jeremy Charles
Published: (2001)
Regulation of vascular endothelial growth factor in prostate cancer
by: de Brot, Simone, et al.
Published: (2015)
by: de Brot, Simone, et al.
Published: (2015)
Effects of omentin on endothelial disruption and hydrogen peroxide-induced inflammation in vascular endothelial cell monolayer
by: Kamaruddin, Nur Aqilah
Published: (2022)
by: Kamaruddin, Nur Aqilah
Published: (2022)
In silico prediction of anticancer activity of Nitrosoureas
by: Noorbatcha, Ibrahim Ali, et al.
Published: (2011)
by: Noorbatcha, Ibrahim Ali, et al.
Published: (2011)
Phyllanthus niruri reduces renal azotaemia in rats induced with chronic renal failure
by: Hamzah, Hazilawati, et al.
Published: (2010)
by: Hamzah, Hazilawati, et al.
Published: (2010)
Expression of circulating CD146 associated with endovascular dysfunction in adenine-induced chronic renal damage in rats using an EvaGreen real-time RT-PCR assay
by: P., Farah Dina, et al.
Published: (2011)
by: P., Farah Dina, et al.
Published: (2011)
Bioenergetic disruption of human micro-vascular endothelial cells by antipsychotics
by: Elmorsy, Ekramy, et al.
Published: (2015)
by: Elmorsy, Ekramy, et al.
Published: (2015)
The effect of magnesium on the inflammatory response in human vascular endothelial cells
by: Almousa, Lujain
Published: (2018)
by: Almousa, Lujain
Published: (2018)
Vascular endothelial growth factor expression in renal cell carcinoma
by: Mohtarrudin, Norhafizah, et al.
Published: (2018)
by: Mohtarrudin, Norhafizah, et al.
Published: (2018)
Malaysian Tualang honey suppresses the angiogenic events in endothelial cells induced by vascular endothelial growth factor
by: Ahmad Firdaus Abdul Khalid,, et al.
Published: (2022)
by: Ahmad Firdaus Abdul Khalid,, et al.
Published: (2022)
Malaysian Tualang Honey suppresses the angiogenic events in Endothelial cells induced by vascular endothelial growth factor
by: Abdul Khalid, Ahmad Firdaus, et al.
Published: (2022)
by: Abdul Khalid, Ahmad Firdaus, et al.
Published: (2022)
Crystal structure of bis[N-(2-hydroxyethyl)-N-methyldithiocarbamato-κ2 S,S′](pyridine)zinc(II) pyridine monosolvate and its N-ethyl analogue
by: Poplaukhin, Pavel, et al.
Published: (2017)
by: Poplaukhin, Pavel, et al.
Published: (2017)
Blood profiles and histopathological changes of liver and kidney tissues from male sprague dawley rats treated with ethanol extracts of Clinacanthus nutans leaf
by: Sajjarattul Nurul Nadia Asyura,, et al.
Published: (2016)
by: Sajjarattul Nurul Nadia Asyura,, et al.
Published: (2016)
Predicting the anticancer activity of seconucleoside nitrosourea analogs
by: Noorbatcha, Ibrahim Ali, et al.
Published: (2009)
by: Noorbatcha, Ibrahim Ali, et al.
Published: (2009)
Benzyl N-[1-(thiophen-2-yl)ethylidene)]-hydrazinecarbodithioate
by: Chan, Eddy Mun Hoe, et al.
Published: (2003)
by: Chan, Eddy Mun Hoe, et al.
Published: (2003)
Vascular endothelial growth factor-A165b ameliorates outer-retinal barrier and vascular dysfunction in the diabetic retina
by: Ved, Nikita, et al.
Published: (2017)
by: Ved, Nikita, et al.
Published: (2017)
The isolation, characterisation and investigation into the In vitro behaviour of human ocular vascular endothelial cells
by: Browning, Andrew C.
Published: (2013)
by: Browning, Andrew C.
Published: (2013)
Cisplatin induced sensory neuropathy is prevented by vascular endothelial growth factor-A
by: Vencappa, Samanta, et al.
Published: (2015)
by: Vencappa, Samanta, et al.
Published: (2015)
Serum vascular endothelial growth
factor (vegf) as a biomarker of lupus
nephritis
by: Iberahim, Rahimah
Published: (2013)
by: Iberahim, Rahimah
Published: (2013)
Crystal structure of 2-methyl-N-{[2-(pyridin-2-yl)ethyl]carbamothioyl}-
benzamide
by: Ameram, Nadiah, et al.
Published: (2015)
by: Ameram, Nadiah, et al.
Published: (2015)
Evaluation of dermal toxicity study of ethanolic extract of Morinda citrifolia fruit in Spraque Dawley rats
by: Mohd Reduan, Mohd Farhan Hanif, et al.
Published: (2021)
by: Mohd Reduan, Mohd Farhan Hanif, et al.
Published: (2021)
Early signs of impaired renal function due to low grade subchronic lead intoxication in rats
by: Mohd Zairi, Nurul Huda, et al.
Published: (2012)
by: Mohd Zairi, Nurul Huda, et al.
Published: (2012)
Similar Items
-
Histopathological features of peripheral T-cell lymphoma in Sprague Dawley rats induced with N-methyl-N-nitrosourea
by: Al-Salih, Hutheyfa A. H., et al.
Published: (2011) -
Chemopreventive effects of garlic powder on N-methyl-N-nitrosourea-induced ductal mammary gland carcinoma in female Sprague Dawley rats
by: Al-Salih, Hutheyfa A. H., et al.
Published: (2015) -
Alteration of serum biochemical parameters and urinalysis in Sprague Dawley rats administered with N-methyl-N-nitrosourea
by: Hakimi, M. K., et al.
Published: (2012) -
Some chemical carcinogens for leukaemia induction and their animal models
by: Aliyu, Abdullahi, et al.
Published: (2019) -
Effects of Morinda citrifolia on early stage of leukaemia in rats
by: Hamzah, Hazilawati, et al.
Published: (2010)