Improved blood glucose level associated with polypeptide-K (Diabegard®), a polypeptide isolated from the seeds of Momordica charantia supplementation: evaluation of 6 cases
To describe six cases of glucose management in diabetic and pre-diabetic patients with Diabegard® supplementation. We report the clinical courses of six individuals taking Diabegard® supplementation at 60 and 120 mg/day for 8 weeks. Patients had a maximum of 50% reduction in fasting blood glucose wi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Global Research Online Publishing House
2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/37973/ http://psasir.upm.edu.my/id/eprint/37973/1/Improved%20blood%20glucose%20level%20associated%20with%20polypeptide-K%20%28Diabegard%C2%AE%29%2C%20a%20polypeptide%20isolated%20from%20the%20seeds%20of%20Momordica%20charantia%20supplementation%20evaluation%20of%206%20cases.pdf |
| _version_ | 1848848749660471296 |
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| author | Yong, Yean Sirn Lee, Cheng Lok Ahmad, Zuraini Abdullah, Muhammad Nazrul Hakim |
| author_facet | Yong, Yean Sirn Lee, Cheng Lok Ahmad, Zuraini Abdullah, Muhammad Nazrul Hakim |
| author_sort | Yong, Yean Sirn |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | To describe six cases of glucose management in diabetic and pre-diabetic patients with Diabegard® supplementation. We report the clinical courses of six individuals taking Diabegard® supplementation at 60 and 120 mg/day for 8 weeks. Patients had a maximum of 50% reduction in fasting blood glucose with 42% reduction in glycated haemoglobin (HbA1c). Patients also had improved kidney functions (expressed by normal level of blood urea nitrogen, creatinine and urine microalbumin). In some patients, these three parameters were elevated prior to supplementation. These results suggest that supplementation of Diabegard® will improve patients' glucose management and with reduction of elevated blood glucose level, kidney functions will also improve. However, patients taking this supplementation are advised to seek medical consultation in monitoring their blood sugar levels. |
| first_indexed | 2025-11-15T09:39:27Z |
| format | Article |
| id | upm-37973 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:39:27Z |
| publishDate | 2014 |
| publisher | Global Research Online Publishing House |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-379732015-12-29T09:11:07Z http://psasir.upm.edu.my/id/eprint/37973/ Improved blood glucose level associated with polypeptide-K (Diabegard®), a polypeptide isolated from the seeds of Momordica charantia supplementation: evaluation of 6 cases Yong, Yean Sirn Lee, Cheng Lok Ahmad, Zuraini Abdullah, Muhammad Nazrul Hakim To describe six cases of glucose management in diabetic and pre-diabetic patients with Diabegard® supplementation. We report the clinical courses of six individuals taking Diabegard® supplementation at 60 and 120 mg/day for 8 weeks. Patients had a maximum of 50% reduction in fasting blood glucose with 42% reduction in glycated haemoglobin (HbA1c). Patients also had improved kidney functions (expressed by normal level of blood urea nitrogen, creatinine and urine microalbumin). In some patients, these three parameters were elevated prior to supplementation. These results suggest that supplementation of Diabegard® will improve patients' glucose management and with reduction of elevated blood glucose level, kidney functions will also improve. However, patients taking this supplementation are advised to seek medical consultation in monitoring their blood sugar levels. Global Research Online Publishing House 2014 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/37973/1/Improved%20blood%20glucose%20level%20associated%20with%20polypeptide-K%20%28Diabegard%C2%AE%29%2C%20a%20polypeptide%20isolated%20from%20the%20seeds%20of%20Momordica%20charantia%20supplementation%20evaluation%20of%206%20cases.pdf Yong, Yean Sirn and Lee, Cheng Lok and Ahmad, Zuraini and Abdullah, Muhammad Nazrul Hakim (2014) Improved blood glucose level associated with polypeptide-K (Diabegard®), a polypeptide isolated from the seeds of Momordica charantia supplementation: evaluation of 6 cases. International Journal of Pharmaceutical Sciences Review and Research, 25 (1). art. no. 25. pp. 147-150. ISSN 0976-044X http://www.globalresearchonline.net/pharmajournal/vol25iss1.aspx |
| spellingShingle | Yong, Yean Sirn Lee, Cheng Lok Ahmad, Zuraini Abdullah, Muhammad Nazrul Hakim Improved blood glucose level associated with polypeptide-K (Diabegard®), a polypeptide isolated from the seeds of Momordica charantia supplementation: evaluation of 6 cases |
| title | Improved blood glucose level associated with polypeptide-K (Diabegard®), a polypeptide isolated from the seeds of Momordica charantia supplementation: evaluation of 6 cases |
| title_full | Improved blood glucose level associated with polypeptide-K (Diabegard®), a polypeptide isolated from the seeds of Momordica charantia supplementation: evaluation of 6 cases |
| title_fullStr | Improved blood glucose level associated with polypeptide-K (Diabegard®), a polypeptide isolated from the seeds of Momordica charantia supplementation: evaluation of 6 cases |
| title_full_unstemmed | Improved blood glucose level associated with polypeptide-K (Diabegard®), a polypeptide isolated from the seeds of Momordica charantia supplementation: evaluation of 6 cases |
| title_short | Improved blood glucose level associated with polypeptide-K (Diabegard®), a polypeptide isolated from the seeds of Momordica charantia supplementation: evaluation of 6 cases |
| title_sort | improved blood glucose level associated with polypeptide-k (diabegard®), a polypeptide isolated from the seeds of momordica charantia supplementation: evaluation of 6 cases |
| url | http://psasir.upm.edu.my/id/eprint/37973/ http://psasir.upm.edu.my/id/eprint/37973/ http://psasir.upm.edu.my/id/eprint/37973/1/Improved%20blood%20glucose%20level%20associated%20with%20polypeptide-K%20%28Diabegard%C2%AE%29%2C%20a%20polypeptide%20isolated%20from%20the%20seeds%20of%20Momordica%20charantia%20supplementation%20evaluation%20of%206%20cases.pdf |