Identification and antibacterial activity of phenolic compounds in crude extracts of Piper sarmentosum (Kadok)

Piper sarmentosum L., locally known as Kadok, is a tropical plant that grows in the wild and in cultivation in Southeast Asia. The plant is known for its medicinal properties and variety of active chemical constituents. The antibacterial capacity of methanolic leaf extracts (25, 50, 100, and 200 mg/...

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Main Authors: Syed Ab Rahman, Sharifah Farhana, Sijam, Kamaruzaman, Omar, Dzolkhifli
Format: Article
Language:English
Published: Oriental Scientific Publishing Company 2014
Online Access:http://psasir.upm.edu.my/id/eprint/37913/
http://psasir.upm.edu.my/id/eprint/37913/1/Identification%20and%20antibacterial%20activity%20of%20phenolic%20compounds%20in%20crude%20extracts%20of%20Piper%20sarmentosum%20%28Kadok%29.pdf
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author Syed Ab Rahman, Sharifah Farhana
Sijam, Kamaruzaman
Omar, Dzolkhifli
author_facet Syed Ab Rahman, Sharifah Farhana
Sijam, Kamaruzaman
Omar, Dzolkhifli
author_sort Syed Ab Rahman, Sharifah Farhana
building UPM Institutional Repository
collection Online Access
description Piper sarmentosum L., locally known as Kadok, is a tropical plant that grows in the wild and in cultivation in Southeast Asia. The plant is known for its medicinal properties and variety of active chemical constituents. The antibacterial capacity of methanolic leaf extracts (25, 50, 100, and 200 mg/mL) of P. sarmentosum and of phenolic standards was screened against gram-negative bacteria Pseudomonas fuscovaginae and Xanthomonas oryzae pv. oryzae, two major pathogens of rice (Oryza sativa L.), by agar-well diffusion and disc-diffusion assays, and compared with that of streptomycin sulfate (30 µg/ml). The inhibition zones for the extracts ranged from 9.0 to 19.33 mm; the minimum inhibitory concentration for both P. fuscovaginae and X. oryzae was 12.5 mg/mL and the minimum bactericidal concentrations were 25.0 and 12.5 mg/mL, respectively. Four phenolic compounds (gallic acid, tannic acid, quercetin, and naringin) were identified and quantified by reversed phase high-performance liquid chromatography diode-array detection (HPLC-DAD). Antibacterial assays indicated that these four compounds were potential natural antimicrobial agents against P. fuscovaginae and X. oryzae. The results presented here suggest that leaf extract of P. sarmentosum has strong potential to serve as a novel bactericide for disease suppression in crop plants.
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spelling upm-379132015-12-29T09:35:56Z http://psasir.upm.edu.my/id/eprint/37913/ Identification and antibacterial activity of phenolic compounds in crude extracts of Piper sarmentosum (Kadok) Syed Ab Rahman, Sharifah Farhana Sijam, Kamaruzaman Omar, Dzolkhifli Piper sarmentosum L., locally known as Kadok, is a tropical plant that grows in the wild and in cultivation in Southeast Asia. The plant is known for its medicinal properties and variety of active chemical constituents. The antibacterial capacity of methanolic leaf extracts (25, 50, 100, and 200 mg/mL) of P. sarmentosum and of phenolic standards was screened against gram-negative bacteria Pseudomonas fuscovaginae and Xanthomonas oryzae pv. oryzae, two major pathogens of rice (Oryza sativa L.), by agar-well diffusion and disc-diffusion assays, and compared with that of streptomycin sulfate (30 µg/ml). The inhibition zones for the extracts ranged from 9.0 to 19.33 mm; the minimum inhibitory concentration for both P. fuscovaginae and X. oryzae was 12.5 mg/mL and the minimum bactericidal concentrations were 25.0 and 12.5 mg/mL, respectively. Four phenolic compounds (gallic acid, tannic acid, quercetin, and naringin) were identified and quantified by reversed phase high-performance liquid chromatography diode-array detection (HPLC-DAD). Antibacterial assays indicated that these four compounds were potential natural antimicrobial agents against P. fuscovaginae and X. oryzae. The results presented here suggest that leaf extract of P. sarmentosum has strong potential to serve as a novel bactericide for disease suppression in crop plants. Oriental Scientific Publishing Company 2014 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/37913/1/Identification%20and%20antibacterial%20activity%20of%20phenolic%20compounds%20in%20crude%20extracts%20of%20Piper%20sarmentosum%20%28Kadok%29.pdf Syed Ab Rahman, Sharifah Farhana and Sijam, Kamaruzaman and Omar, Dzolkhifli (2014) Identification and antibacterial activity of phenolic compounds in crude extracts of Piper sarmentosum (Kadok). Journal of Pure and Applied Microbiology, 8 (spec.). pp. 483-490. ISSN 0973-7510 http://microbiologyjournal.org/jmabsread.php?snoid=2273&month=&year=
spellingShingle Syed Ab Rahman, Sharifah Farhana
Sijam, Kamaruzaman
Omar, Dzolkhifli
Identification and antibacterial activity of phenolic compounds in crude extracts of Piper sarmentosum (Kadok)
title Identification and antibacterial activity of phenolic compounds in crude extracts of Piper sarmentosum (Kadok)
title_full Identification and antibacterial activity of phenolic compounds in crude extracts of Piper sarmentosum (Kadok)
title_fullStr Identification and antibacterial activity of phenolic compounds in crude extracts of Piper sarmentosum (Kadok)
title_full_unstemmed Identification and antibacterial activity of phenolic compounds in crude extracts of Piper sarmentosum (Kadok)
title_short Identification and antibacterial activity of phenolic compounds in crude extracts of Piper sarmentosum (Kadok)
title_sort identification and antibacterial activity of phenolic compounds in crude extracts of piper sarmentosum (kadok)
url http://psasir.upm.edu.my/id/eprint/37913/
http://psasir.upm.edu.my/id/eprint/37913/
http://psasir.upm.edu.my/id/eprint/37913/1/Identification%20and%20antibacterial%20activity%20of%20phenolic%20compounds%20in%20crude%20extracts%20of%20Piper%20sarmentosum%20%28Kadok%29.pdf