Factors affecting particle collection by electro-osmosis in microfluidic systems

Alternating-current electro-osmosis, a phenomenon of fluid transport due to the interaction between an electrical double layer and a tangential electric field, has been used both for inducing fluid movement and for the concentration of particles suspended in the fluid. This offers many advantages ov...

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Main Authors: Mohtar, Mohd Nazim, Hoettges, Kai Friedrich, Hughes, Michael Pycraft
Format: Article
Language:English
Published: Wiley-VCH Verlag 2014
Online Access:http://psasir.upm.edu.my/id/eprint/37617/
http://psasir.upm.edu.my/id/eprint/37617/1/Factors%20affecting%20particle%20collection%20by%20electro-osmosis%20in%20microfluidic%20systems.pdf
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author Mohtar, Mohd Nazim
Hoettges, Kai Friedrich
Hughes, Michael Pycraft
author_facet Mohtar, Mohd Nazim
Hoettges, Kai Friedrich
Hughes, Michael Pycraft
author_sort Mohtar, Mohd Nazim
building UPM Institutional Repository
collection Online Access
description Alternating-current electro-osmosis, a phenomenon of fluid transport due to the interaction between an electrical double layer and a tangential electric field, has been used both for inducing fluid movement and for the concentration of particles suspended in the fluid. This offers many advantages over other phenomena used to trap particles, such as placing particles at an electrode centre rather than an edge; benefits of scale, where electrodes hundreds of micrometers across can trap particles from the molecules to cells at the same rate; and a trapping volume limited by the vortex height, a phenomenon thus far unstudied. In this paper, the collection of particles due to alternating-current electro-osmosis driven collection is examined for a range of particle concentrations, inter-electrode gap widths, chamber heights and media viscosity and density. A model of collection behaviour is described where particle collection over time is governed by two processes, one driven by the vortices and the other by sedimentation, allowing the determination of the maximum height of vortex-driven collection, but also indicates how trapping is limited by high particle concentrations and fluid velocities. The results also indicate that viscosity, rather than density, is a significant governing factor in determining the trapping behaviour of particles.
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spelling upm-376172016-01-12T07:42:22Z http://psasir.upm.edu.my/id/eprint/37617/ Factors affecting particle collection by electro-osmosis in microfluidic systems Mohtar, Mohd Nazim Hoettges, Kai Friedrich Hughes, Michael Pycraft Alternating-current electro-osmosis, a phenomenon of fluid transport due to the interaction between an electrical double layer and a tangential electric field, has been used both for inducing fluid movement and for the concentration of particles suspended in the fluid. This offers many advantages over other phenomena used to trap particles, such as placing particles at an electrode centre rather than an edge; benefits of scale, where electrodes hundreds of micrometers across can trap particles from the molecules to cells at the same rate; and a trapping volume limited by the vortex height, a phenomenon thus far unstudied. In this paper, the collection of particles due to alternating-current electro-osmosis driven collection is examined for a range of particle concentrations, inter-electrode gap widths, chamber heights and media viscosity and density. A model of collection behaviour is described where particle collection over time is governed by two processes, one driven by the vortices and the other by sedimentation, allowing the determination of the maximum height of vortex-driven collection, but also indicates how trapping is limited by high particle concentrations and fluid velocities. The results also indicate that viscosity, rather than density, is a significant governing factor in determining the trapping behaviour of particles. Wiley-VCH Verlag 2014-02 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/37617/1/Factors%20affecting%20particle%20collection%20by%20electro-osmosis%20in%20microfluidic%20systems.pdf Mohtar, Mohd Nazim and Hoettges, Kai Friedrich and Hughes, Michael Pycraft (2014) Factors affecting particle collection by electro-osmosis in microfluidic systems. Electrophoresis, 35 (2-3). pp. 345-351. ISSN 0173-0835; ESSN: 1522-2683 http://onlinelibrary.wiley.com/doi/10.1002/elps.201300420/abstract;jsessionid=43A6F813DF707244EA4FA364CE53E6B5.f02t04 10.1002/elps.201300420
spellingShingle Mohtar, Mohd Nazim
Hoettges, Kai Friedrich
Hughes, Michael Pycraft
Factors affecting particle collection by electro-osmosis in microfluidic systems
title Factors affecting particle collection by electro-osmosis in microfluidic systems
title_full Factors affecting particle collection by electro-osmosis in microfluidic systems
title_fullStr Factors affecting particle collection by electro-osmosis in microfluidic systems
title_full_unstemmed Factors affecting particle collection by electro-osmosis in microfluidic systems
title_short Factors affecting particle collection by electro-osmosis in microfluidic systems
title_sort factors affecting particle collection by electro-osmosis in microfluidic systems
url http://psasir.upm.edu.my/id/eprint/37617/
http://psasir.upm.edu.my/id/eprint/37617/
http://psasir.upm.edu.my/id/eprint/37617/
http://psasir.upm.edu.my/id/eprint/37617/1/Factors%20affecting%20particle%20collection%20by%20electro-osmosis%20in%20microfluidic%20systems.pdf