Effect of dabai (Canarium odontophyllum) fruit extract on biochemical parameters of induced obese–diabetic rats
Dabai is one of the most popular indigenous fruits in Sarawak, and is rich in various nutrients. In this study, the effect of dabai fruit extract (300 and 600 mg/kg bw) on the biochemical parameters of obese–diabetic (Ob-db) rats was investigated. After a 4-week treatment period, the dabai extract a...
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| Format: | Article |
| Language: | English |
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Elsevier
2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/37219/ http://psasir.upm.edu.my/id/eprint/37219/1/Effect%20of%20dabai.pdf |
| _version_ | 1848848549924569088 |
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| author | Mokiran, Nurul Nadirah Ismail, Amin Azlan, Azrina Hamid, Muhajir Hassan, Fouad Abdulrahman |
| author_facet | Mokiran, Nurul Nadirah Ismail, Amin Azlan, Azrina Hamid, Muhajir Hassan, Fouad Abdulrahman |
| author_sort | Mokiran, Nurul Nadirah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Dabai is one of the most popular indigenous fruits in Sarawak, and is rich in various nutrients. In this study, the effect of dabai fruit extract (300 and 600 mg/kg bw) on the biochemical parameters of obese–diabetic (Ob-db) rats was investigated. After a 4-week treatment period, the dabai extract at a concentration of 600 mg/kg bw (equivalent to 20 g of flesh with skin of fresh fruit) showed a pronounced effect in lowering the plasma glucose level compared with 300 mg extract/kg bw (equivalent to 10 g of flesh with skin of fresh fruit). The dabai extract also significantly reduced the plasma cholesterol and low-density lipoprotein (LDL-c) levels and increased high-density lipoprotein (HDL-c). However, the dabai extract did not increase the insulin level but did increase its sensitivity and reduced insulin resistance (HOMA-IR). This study suggests that dabai extract possesses hypocholesterolaemic properties, has a short-term glucose-lowering effect and improves the lipid profile through synergistic effect of various polyphenols. |
| first_indexed | 2025-11-15T09:36:16Z |
| format | Article |
| id | upm-37219 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:36:16Z |
| publishDate | 2014 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-372192015-10-06T03:39:18Z http://psasir.upm.edu.my/id/eprint/37219/ Effect of dabai (Canarium odontophyllum) fruit extract on biochemical parameters of induced obese–diabetic rats Mokiran, Nurul Nadirah Ismail, Amin Azlan, Azrina Hamid, Muhajir Hassan, Fouad Abdulrahman Dabai is one of the most popular indigenous fruits in Sarawak, and is rich in various nutrients. In this study, the effect of dabai fruit extract (300 and 600 mg/kg bw) on the biochemical parameters of obese–diabetic (Ob-db) rats was investigated. After a 4-week treatment period, the dabai extract at a concentration of 600 mg/kg bw (equivalent to 20 g of flesh with skin of fresh fruit) showed a pronounced effect in lowering the plasma glucose level compared with 300 mg extract/kg bw (equivalent to 10 g of flesh with skin of fresh fruit). The dabai extract also significantly reduced the plasma cholesterol and low-density lipoprotein (LDL-c) levels and increased high-density lipoprotein (HDL-c). However, the dabai extract did not increase the insulin level but did increase its sensitivity and reduced insulin resistance (HOMA-IR). This study suggests that dabai extract possesses hypocholesterolaemic properties, has a short-term glucose-lowering effect and improves the lipid profile through synergistic effect of various polyphenols. Elsevier 2014-05 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/37219/1/Effect%20of%20dabai.pdf Mokiran, Nurul Nadirah and Ismail, Amin and Azlan, Azrina and Hamid, Muhajir and Hassan, Fouad Abdulrahman (2014) Effect of dabai (Canarium odontophyllum) fruit extract on biochemical parameters of induced obese–diabetic rats. Journal of Functional Foods, 8. pp. 139-149. ISSN 1756-4646; ESSN: 2214-9414 10.1016/j.jff.2014.03.007 |
| spellingShingle | Mokiran, Nurul Nadirah Ismail, Amin Azlan, Azrina Hamid, Muhajir Hassan, Fouad Abdulrahman Effect of dabai (Canarium odontophyllum) fruit extract on biochemical parameters of induced obese–diabetic rats |
| title | Effect of dabai (Canarium odontophyllum) fruit extract on biochemical parameters of induced obese–diabetic rats |
| title_full | Effect of dabai (Canarium odontophyllum) fruit extract on biochemical parameters of induced obese–diabetic rats |
| title_fullStr | Effect of dabai (Canarium odontophyllum) fruit extract on biochemical parameters of induced obese–diabetic rats |
| title_full_unstemmed | Effect of dabai (Canarium odontophyllum) fruit extract on biochemical parameters of induced obese–diabetic rats |
| title_short | Effect of dabai (Canarium odontophyllum) fruit extract on biochemical parameters of induced obese–diabetic rats |
| title_sort | effect of dabai (canarium odontophyllum) fruit extract on biochemical parameters of induced obese–diabetic rats |
| url | http://psasir.upm.edu.my/id/eprint/37219/ http://psasir.upm.edu.my/id/eprint/37219/ http://psasir.upm.edu.my/id/eprint/37219/1/Effect%20of%20dabai.pdf |