Dillenia species: a review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies

Context: Dillenia (Dilleniaceae) is a genus of about 100 species of flowering plants in tropical and subtropical trees of Southern Asia, Australasia, and the Indian Ocean Islands. Until now, only eight Dillenia species have been reported to be used traditionally in different countries for various me...

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Main Authors: Saiful Yazan, Latifah, Armania, Nurdin
Format: Article
Language:English
Published: Informa Healthcare 2014
Online Access:http://psasir.upm.edu.my/id/eprint/37110/
http://psasir.upm.edu.my/id/eprint/37110/1/Dillenia%20species.pdf
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author Saiful Yazan, Latifah
Armania, Nurdin
author_facet Saiful Yazan, Latifah
Armania, Nurdin
author_sort Saiful Yazan, Latifah
building UPM Institutional Repository
collection Online Access
description Context: Dillenia (Dilleniaceae) is a genus of about 100 species of flowering plants in tropical and subtropical trees of Southern Asia, Australasia, and the Indian Ocean Islands. Until now, only eight Dillenia species have been reported to be used traditionally in different countries for various medical purposes. Out of eight species, D. pentagyna (Roxb), D. indica (Linn.) and D. suffruticosa (Griffith Ex. Hook. F. & Thomsom Martelli) have been reported to be used to treat cancerous growth. Objective: The present review explored and provided information on the therapeutic potential of Dillenia species. Methods: Comprehensive and relevant literature on the therapeutic potential of Dillenia species was gathered through electronic databases including Google Scholar, Scopus, PubMed, and books, without limiting the dates of publication. Results and conclusion: The review demonstrated that only a few Dillenia species have been proven scientifically for their therapeutic potential in pre-clinical studies, including D. pentagyna, D. indica, D. papuana (Martelli), D. meliosmifolia (Hook. F. Ex. Thomsom) and D. suffruticosa (Griffith Ex Hook. F. & Thomson). A few species of Dillenia have undergone isolation and characterization of compounds with lupeol and betulinic acids having tremendous pharmacological potential. Dillenia species warrant further studies on their therapeutic potential, which may eventually lead to the development of new drug candidates for treatment of various diseases.
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spelling upm-371102016-01-27T01:18:50Z http://psasir.upm.edu.my/id/eprint/37110/ Dillenia species: a review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies Saiful Yazan, Latifah Armania, Nurdin Context: Dillenia (Dilleniaceae) is a genus of about 100 species of flowering plants in tropical and subtropical trees of Southern Asia, Australasia, and the Indian Ocean Islands. Until now, only eight Dillenia species have been reported to be used traditionally in different countries for various medical purposes. Out of eight species, D. pentagyna (Roxb), D. indica (Linn.) and D. suffruticosa (Griffith Ex. Hook. F. & Thomsom Martelli) have been reported to be used to treat cancerous growth. Objective: The present review explored and provided information on the therapeutic potential of Dillenia species. Methods: Comprehensive and relevant literature on the therapeutic potential of Dillenia species was gathered through electronic databases including Google Scholar, Scopus, PubMed, and books, without limiting the dates of publication. Results and conclusion: The review demonstrated that only a few Dillenia species have been proven scientifically for their therapeutic potential in pre-clinical studies, including D. pentagyna, D. indica, D. papuana (Martelli), D. meliosmifolia (Hook. F. Ex. Thomsom) and D. suffruticosa (Griffith Ex Hook. F. & Thomson). A few species of Dillenia have undergone isolation and characterization of compounds with lupeol and betulinic acids having tremendous pharmacological potential. Dillenia species warrant further studies on their therapeutic potential, which may eventually lead to the development of new drug candidates for treatment of various diseases. Informa Healthcare 2014 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/37110/1/Dillenia%20species.pdf Saiful Yazan, Latifah and Armania, Nurdin (2014) Dillenia species: a review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies. Pharmaceutical Biology, 52 (7). pp. 890-897. ISSN 1388-0209; ESSN: 1744-5116 10.3109/13880209.2013.872672
spellingShingle Saiful Yazan, Latifah
Armania, Nurdin
Dillenia species: a review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies
title Dillenia species: a review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies
title_full Dillenia species: a review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies
title_fullStr Dillenia species: a review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies
title_full_unstemmed Dillenia species: a review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies
title_short Dillenia species: a review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies
title_sort dillenia species: a review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies
url http://psasir.upm.edu.my/id/eprint/37110/
http://psasir.upm.edu.my/id/eprint/37110/
http://psasir.upm.edu.my/id/eprint/37110/1/Dillenia%20species.pdf