Localized Castleman's disease presenting as a vascular right iliac fossa mass

Castleman's disease is a rare lymphoproliferative disorder of unknown aetiology. The presentation is varied, diagnosis is difficult, and optimum management is still unknown. We report our experience with a case of Castleman's disease in a 34-year-old woman who presented with pallor, hepato...

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Main Authors: Abdullah, Khairul Muhsein, Liew, Ngoh Chin, Al-Azawi, Abd Al-Rhman Hikmet Shaker, Abdul Wahab, Shahrin Iskandar
Format: Article
Language:English
Published: Elsevier 2004
Online Access:http://psasir.upm.edu.my/id/eprint/36676/
http://psasir.upm.edu.my/id/eprint/36676/1/Localized%20Castleman%27s%20disease%20presenting%20as%20a%20vascular%20right%20iliac%20fossa%20mass.pdf
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author Abdullah, Khairul Muhsein
Liew, Ngoh Chin
Al-Azawi, Abd Al-Rhman Hikmet Shaker
Abdul Wahab, Shahrin Iskandar
author_facet Abdullah, Khairul Muhsein
Liew, Ngoh Chin
Al-Azawi, Abd Al-Rhman Hikmet Shaker
Abdul Wahab, Shahrin Iskandar
author_sort Abdullah, Khairul Muhsein
building UPM Institutional Repository
collection Online Access
description Castleman's disease is a rare lymphoproliferative disorder of unknown aetiology. The presentation is varied, diagnosis is difficult, and optimum management is still unknown. We report our experience with a case of Castleman's disease in a 34-year-old woman who presented with pallor, hepatosplenomegaly, and a right iliac fossa mass that was 5 cm in diameter. This was initially diagnosed as a soft tissue sarcoma and preoperative tumour embolization was planned before excision. Mesenteric arteriogram revealed that the feeder arteries arose from the superior mesenteric artery and embolization was aborted for fear of causing bowel ischaemia. On laparotomy, lymphoid enlargement was found between the leaves of the jejunal mesentery. The tumour was relatively avascular and the overlying mesenteric vessels contributed to the duplex ultrasound and computerized tomography appearance of hypervascularity. The tumour with the mesentery and the overlying segment of jejunum was excised completely. Histopathology confirmed Castleman's disease. The purpose of this report is to present this rare case that caused a diagnostic dilemma and to review the management of this disorder.
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spelling upm-366762016-04-07T06:59:35Z http://psasir.upm.edu.my/id/eprint/36676/ Localized Castleman's disease presenting as a vascular right iliac fossa mass Abdullah, Khairul Muhsein Liew, Ngoh Chin Al-Azawi, Abd Al-Rhman Hikmet Shaker Abdul Wahab, Shahrin Iskandar Castleman's disease is a rare lymphoproliferative disorder of unknown aetiology. The presentation is varied, diagnosis is difficult, and optimum management is still unknown. We report our experience with a case of Castleman's disease in a 34-year-old woman who presented with pallor, hepatosplenomegaly, and a right iliac fossa mass that was 5 cm in diameter. This was initially diagnosed as a soft tissue sarcoma and preoperative tumour embolization was planned before excision. Mesenteric arteriogram revealed that the feeder arteries arose from the superior mesenteric artery and embolization was aborted for fear of causing bowel ischaemia. On laparotomy, lymphoid enlargement was found between the leaves of the jejunal mesentery. The tumour was relatively avascular and the overlying mesenteric vessels contributed to the duplex ultrasound and computerized tomography appearance of hypervascularity. The tumour with the mesentery and the overlying segment of jejunum was excised completely. Histopathology confirmed Castleman's disease. The purpose of this report is to present this rare case that caused a diagnostic dilemma and to review the management of this disorder. Elsevier 2004-01 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/36676/1/Localized%20Castleman%27s%20disease%20presenting%20as%20a%20vascular%20right%20iliac%20fossa%20mass.pdf Abdullah, Khairul Muhsein and Liew, Ngoh Chin and Al-Azawi, Abd Al-Rhman Hikmet Shaker and Abdul Wahab, Shahrin Iskandar (2004) Localized Castleman's disease presenting as a vascular right iliac fossa mass. Asian Journal of Surgery, 27 (1). pp. 54-57. ISSN 1015-9584; ESSN: 0219-3108 http://www.sciencedirect.com/science/article/pii/S1015958409602463 10.1016/S1015-9584(09)60246-3
spellingShingle Abdullah, Khairul Muhsein
Liew, Ngoh Chin
Al-Azawi, Abd Al-Rhman Hikmet Shaker
Abdul Wahab, Shahrin Iskandar
Localized Castleman's disease presenting as a vascular right iliac fossa mass
title Localized Castleman's disease presenting as a vascular right iliac fossa mass
title_full Localized Castleman's disease presenting as a vascular right iliac fossa mass
title_fullStr Localized Castleman's disease presenting as a vascular right iliac fossa mass
title_full_unstemmed Localized Castleman's disease presenting as a vascular right iliac fossa mass
title_short Localized Castleman's disease presenting as a vascular right iliac fossa mass
title_sort localized castleman's disease presenting as a vascular right iliac fossa mass
url http://psasir.upm.edu.my/id/eprint/36676/
http://psasir.upm.edu.my/id/eprint/36676/
http://psasir.upm.edu.my/id/eprint/36676/
http://psasir.upm.edu.my/id/eprint/36676/1/Localized%20Castleman%27s%20disease%20presenting%20as%20a%20vascular%20right%20iliac%20fossa%20mass.pdf