Asymmetric Michael reaction catalyzed by mimicked peptides

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Asymmetric Michael reaction catalyzed by mimicked peptides

Peptides mimicked from active site of promiscuous aldo-ketoreductase were synthesized and tested as asymmetry catalysts in the Michael adduct reaction of aldehydes or ketones with nitroolefins to furnish the corresponding γ-nitroaldehydes, γ-nitroketones with up to 93 % yield, 99:1 dr and 71 % ee at...

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Bibliographic Details
Main Authors:	Bayat, Saadi, Tejo, Bimo Ario, Salleh, Abu Bakar, Abd. Malek, Emilia, Mohd Yahaya, Normi, Abdul Rahman, Mohd Basyaruddin
Format:	Article
Language:	English
Published:	Springer 2014
Online Access:	http://psasir.upm.edu.my/id/eprint/36591/ http://psasir.upm.edu.my/id/eprint/36591/1/Asymmetric%20Michael%20reaction%20catalyzed%20by%20mimicked%20peptides.pdf

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