Antibiotic prophylaxis in elective colorectal surgery

Background: Antibiotics are often administered in elective colorectal surgery to prevent wound infection. The tendency for surgeons to prolong the administration of prophylactic antibiotic therapy in the postoperative period is a well-known fact. The aim of this study was to elucidate the pattern of...

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Main Authors: Alif Gul, Yunus Gul, Lee, H. Lian, Jabar, Mohd Faisal, Moissinac, Kevin
Format: Article
Language:English
English
Published: Royal Australasian College of Surgeons 2002
Online Access:http://psasir.upm.edu.my/id/eprint/36538/
http://psasir.upm.edu.my/id/eprint/36538/1/Antibiotic%20prophylaxis%20in%20elective%20colorectal%20surgery.pdf
http://psasir.upm.edu.my/id/eprint/36538/7/ANZ%20Journal%20of%20Surgery%20-%202002%20-%20Gul%20-%20Antibiotic%20prophylaxis%20in%20elective%20colorectal%20surgery.pdf
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author Alif Gul, Yunus Gul
Lee, H. Lian
Jabar, Mohd Faisal
Moissinac, Kevin
author_facet Alif Gul, Yunus Gul
Lee, H. Lian
Jabar, Mohd Faisal
Moissinac, Kevin
author_sort Alif Gul, Yunus Gul
building UPM Institutional Repository
collection Online Access
description Background: Antibiotics are often administered in elective colorectal surgery to prevent wound infection. The tendency for surgeons to prolong the administration of prophylactic antibiotic therapy in the postoperative period is a well-known fact. The aim of this study was to elucidate the pattern of prophylactic antibiotic utilization in elective colorectal surgery and to determine if evidence-based medicine is employed in relation to this practice. Methods: A cross-sectional study encompassing general surgeons performing elective colorectal surgery was performed. Questionnaires were distributed to 144 surgeons (national, academic and private health care). Questions pertaining to the type, timing and duration of antibiotic administration were asked. The prevalence of wound infection audit rate and whether or not there were specific guidelines related to antibiotic administration were also determined. Results: The response rate obtained was 67% (n = 96). Although evidence from the current medical literature and recommended national guidelines support the use of single-dose prophylactic antibiotics, 72% of the respondents used more than a single dose. Forty surgeons (42%) claimed that their prescribing practice was supported by the medical literature, 31 respondents (32%) based their practice on hospital guidelines and personal preference was cited as a reason by 21 surgeons (22%). The remaining four respondents (4%) used a similar scheduling policy to that practiced by their colleagues in relation to antibiotic administration. There was no significant difference in antibiotic dose scheduling between national, private and university academic institutions (P = 0.85). Conclusions: These results suggest that a significant proportion of surgeons administer excessive and unnecessary doses of antibiotics in elective colorectal surgery. Further studies are required to uncover the reasons but lack of appropriate guidelines and failure to exercise evidence-based medicine are major factors that account for this practice.
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spelling upm-365382024-08-07T06:32:59Z http://psasir.upm.edu.my/id/eprint/36538/ Antibiotic prophylaxis in elective colorectal surgery Alif Gul, Yunus Gul Lee, H. Lian Jabar, Mohd Faisal Moissinac, Kevin Background: Antibiotics are often administered in elective colorectal surgery to prevent wound infection. The tendency for surgeons to prolong the administration of prophylactic antibiotic therapy in the postoperative period is a well-known fact. The aim of this study was to elucidate the pattern of prophylactic antibiotic utilization in elective colorectal surgery and to determine if evidence-based medicine is employed in relation to this practice. Methods: A cross-sectional study encompassing general surgeons performing elective colorectal surgery was performed. Questionnaires were distributed to 144 surgeons (national, academic and private health care). Questions pertaining to the type, timing and duration of antibiotic administration were asked. The prevalence of wound infection audit rate and whether or not there were specific guidelines related to antibiotic administration were also determined. Results: The response rate obtained was 67% (n = 96). Although evidence from the current medical literature and recommended national guidelines support the use of single-dose prophylactic antibiotics, 72% of the respondents used more than a single dose. Forty surgeons (42%) claimed that their prescribing practice was supported by the medical literature, 31 respondents (32%) based their practice on hospital guidelines and personal preference was cited as a reason by 21 surgeons (22%). The remaining four respondents (4%) used a similar scheduling policy to that practiced by their colleagues in relation to antibiotic administration. There was no significant difference in antibiotic dose scheduling between national, private and university academic institutions (P = 0.85). Conclusions: These results suggest that a significant proportion of surgeons administer excessive and unnecessary doses of antibiotics in elective colorectal surgery. Further studies are required to uncover the reasons but lack of appropriate guidelines and failure to exercise evidence-based medicine are major factors that account for this practice. Royal Australasian College of Surgeons 2002-04 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/36538/1/Antibiotic%20prophylaxis%20in%20elective%20colorectal%20surgery.pdf text en http://psasir.upm.edu.my/id/eprint/36538/7/ANZ%20Journal%20of%20Surgery%20-%202002%20-%20Gul%20-%20Antibiotic%20prophylaxis%20in%20elective%20colorectal%20surgery.pdf Alif Gul, Yunus Gul and Lee, H. Lian and Jabar, Mohd Faisal and Moissinac, Kevin (2002) Antibiotic prophylaxis in elective colorectal surgery. ANZ Journal of Surgery, 72 (4). pp. 275-278. ISSN 1445-1433; ESSN: 1445-2197 http://onlinelibrary.wiley.com/doi/10.1046/j.1445-2197.2002.02365.x/abstract;jsessionid=3DC49CD8F5979368D7D256E3D8138CF0.f03t04?systemMessage=Wiley+Online+Library+will+be+unavailable+on+Saturday+27th+February+from+09%3A00-14%3A00+GMT+%2F+04%3A00-09%3A00+E 10.1046/j.1445-2197.2002.02365.x
spellingShingle Alif Gul, Yunus Gul
Lee, H. Lian
Jabar, Mohd Faisal
Moissinac, Kevin
Antibiotic prophylaxis in elective colorectal surgery
title Antibiotic prophylaxis in elective colorectal surgery
title_full Antibiotic prophylaxis in elective colorectal surgery
title_fullStr Antibiotic prophylaxis in elective colorectal surgery
title_full_unstemmed Antibiotic prophylaxis in elective colorectal surgery
title_short Antibiotic prophylaxis in elective colorectal surgery
title_sort antibiotic prophylaxis in elective colorectal surgery
url http://psasir.upm.edu.my/id/eprint/36538/
http://psasir.upm.edu.my/id/eprint/36538/
http://psasir.upm.edu.my/id/eprint/36538/
http://psasir.upm.edu.my/id/eprint/36538/1/Antibiotic%20prophylaxis%20in%20elective%20colorectal%20surgery.pdf
http://psasir.upm.edu.my/id/eprint/36538/7/ANZ%20Journal%20of%20Surgery%20-%202002%20-%20Gul%20-%20Antibiotic%20prophylaxis%20in%20elective%20colorectal%20surgery.pdf