Are bioactive-rich fractions functionally richer?

Plant bioresources are relied upon as natural, inexpensive, and sustainable remedies for the management of several chronic diseases worldwide. Plants have historically been consumed for medicinal purposes based on traditional belief, but this trend is currently changing. The growing interest in the...

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Main Authors: Imam, Mustapha Umar, Ismail, Maznah, Ooi, Der Jiun, Azmi, Nur Hanisah, Nadarajan, Sarega, Chan, Kim Wei, Bhanger, Muhammad Iqbal
Format: Article
Language:English
Published: Informa Healthcare 2016
Online Access:http://psasir.upm.edu.my/id/eprint/36533/
http://psasir.upm.edu.my/id/eprint/36533/1/Are%20bioactive.pdf
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author Imam, Mustapha Umar
Ismail, Maznah
Ooi, Der Jiun
Azmi, Nur Hanisah
Nadarajan, Sarega
Chan, Kim Wei
Bhanger, Muhammad Iqbal
author_facet Imam, Mustapha Umar
Ismail, Maznah
Ooi, Der Jiun
Azmi, Nur Hanisah
Nadarajan, Sarega
Chan, Kim Wei
Bhanger, Muhammad Iqbal
author_sort Imam, Mustapha Umar
building UPM Institutional Repository
collection Online Access
description Plant bioresources are relied upon as natural, inexpensive, and sustainable remedies for the management of several chronic diseases worldwide. Plants have historically been consumed for medicinal purposes based on traditional belief, but this trend is currently changing. The growing interest in the medicinal properties of plant bioresources stems from concerns of side effects and other adverse effects caused by synthetic drugs. This interest has yielded a better understanding of the roles of plant bioactive compounds in health promotion and disease prevention, including the underlying mechanisms involved in such functional effects. The desire to maximize the potential of phytochemicals has led to the development of “rich fractions,” in which extracts contain bioactive compounds in addition to elevated levels of the primary compound. Although a rich fraction effectively increases the bioactivity of the extract, the standardization and quality assurance process can be challenging. However, the supercritical fluid extraction (SFE) system is a promising green technology in this regard. Future clinical and pharmacological studies are needed to fully elucidate the implications of these preparations in the management of human diseases, thereby fostering a move toward evidence-based medicine.
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spelling upm-365332017-02-07T07:50:06Z http://psasir.upm.edu.my/id/eprint/36533/ Are bioactive-rich fractions functionally richer? Imam, Mustapha Umar Ismail, Maznah Ooi, Der Jiun Azmi, Nur Hanisah Nadarajan, Sarega Chan, Kim Wei Bhanger, Muhammad Iqbal Plant bioresources are relied upon as natural, inexpensive, and sustainable remedies for the management of several chronic diseases worldwide. Plants have historically been consumed for medicinal purposes based on traditional belief, but this trend is currently changing. The growing interest in the medicinal properties of plant bioresources stems from concerns of side effects and other adverse effects caused by synthetic drugs. This interest has yielded a better understanding of the roles of plant bioactive compounds in health promotion and disease prevention, including the underlying mechanisms involved in such functional effects. The desire to maximize the potential of phytochemicals has led to the development of “rich fractions,” in which extracts contain bioactive compounds in addition to elevated levels of the primary compound. Although a rich fraction effectively increases the bioactivity of the extract, the standardization and quality assurance process can be challenging. However, the supercritical fluid extraction (SFE) system is a promising green technology in this regard. Future clinical and pharmacological studies are needed to fully elucidate the implications of these preparations in the management of human diseases, thereby fostering a move toward evidence-based medicine. Informa Healthcare 2016 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/36533/1/Are%20bioactive.pdf Imam, Mustapha Umar and Ismail, Maznah and Ooi, Der Jiun and Azmi, Nur Hanisah and Nadarajan, Sarega and Chan, Kim Wei and Bhanger, Muhammad Iqbal (2016) Are bioactive-rich fractions functionally richer? Critical Reviews in Biotechnology, 36 (4). pp. 585-593. ISSN 0738-8551; ESSN: 1549-7801 http://www.tandfonline.com/doi/abs/10.3109/07388551.2014.995586?journalCode=ibty20 10.3109/07388551.2014.995586
spellingShingle Imam, Mustapha Umar
Ismail, Maznah
Ooi, Der Jiun
Azmi, Nur Hanisah
Nadarajan, Sarega
Chan, Kim Wei
Bhanger, Muhammad Iqbal
Are bioactive-rich fractions functionally richer?
title Are bioactive-rich fractions functionally richer?
title_full Are bioactive-rich fractions functionally richer?
title_fullStr Are bioactive-rich fractions functionally richer?
title_full_unstemmed Are bioactive-rich fractions functionally richer?
title_short Are bioactive-rich fractions functionally richer?
title_sort are bioactive-rich fractions functionally richer?
url http://psasir.upm.edu.my/id/eprint/36533/
http://psasir.upm.edu.my/id/eprint/36533/
http://psasir.upm.edu.my/id/eprint/36533/
http://psasir.upm.edu.my/id/eprint/36533/1/Are%20bioactive.pdf