Antiproliferation and induction of caspase-8-dependent mitochondria-mediated apoptosis by β-tocotrienol in human lung and brain cancer cell lines
The pure vitamin isomer, β-tocotrienol has the least abundance among the other vitamin E isomers that are present in numerous plants. Hence, it is very scarcely studied for its bioactivity. In this study, the antiproliferative effects and primary apoptotic mechanisms of β-tocotrienol on human lung a...
| Main Authors: | Lim, Su Wen, Loh, Hwei San, Ting, Kang Nee, Bradshaw, Tracey Dawn, Allaudin, Zeenathul Nazariah |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2014
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/36497/ http://psasir.upm.edu.my/id/eprint/36497/1/Exotic%20berries%20as%20a%20functional%20food.pdf |
Similar Items
Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cells
by: Lim, Su Wen, et al.
Published: (2014)
by: Lim, Su Wen, et al.
Published: (2014)
Zerumbone induces apoptosis in Jurkat T-cell line via activation of caspase 3 and caspase 9
by: Rahman, Heshu Sulaiman, et al.
Published: (2012)
by: Rahman, Heshu Sulaiman, et al.
Published: (2012)
Acalypha wilkesiana ethyl acetate extract enhances the in vitro cytotoxic effects of α-tocopherol in human brain and lung cancer cells
by: Lim, Su Wen, et al.
Published: (2013)
by: Lim, Su Wen, et al.
Published: (2013)
Acalypha wilkesiana extracts induce apoptosis by causing single strand and double strand DNA breaks
by: Lim, Su Wen, et al.
Published: (2011)
by: Lim, Su Wen, et al.
Published: (2011)
Induction of apoptosis in MCF-7 cells via oxidative stress generation, mitochondria-dependent and caspase-independent pathway by ethyl acetate extract of Dillenia suffruticosa and its chemical profile
by: Tor, Yin Sim, et al.
Published: (2015)
by: Tor, Yin Sim, et al.
Published: (2015)
Water extract of brewers' rice induces antiproliferation of human colorectal cancer (HT-29) cell lines via the induction of apoptosis
by: Tan, Bee Ling, et al.
Published: (2015)
by: Tan, Bee Ling, et al.
Published: (2015)
Water extract of brewers rice induces antiproliferation of human colorectal cancer (HT-29) cell lines via the induction of apoptosis
by: Bee, Ling Tan, et al.
Published: (2015)
by: Bee, Ling Tan, et al.
Published: (2015)
Reduction of MTT to purple formazan by vitamin E isomers in the absence of cells
by: Lim, Su Wen, et al.
Published: (2015)
by: Lim, Su Wen, et al.
Published: (2015)
Induction of Caspase-2 Activation by a DNA Enzyme Evokes Tumor Cell Apoptosis
by: Kim, Soo-Hyun, et al.
Published: (2012)
by: Kim, Soo-Hyun, et al.
Published: (2012)
Apoptosis pathways induced by recombinant adenovirus in cancer cells
by: Koh, Choo Yan, et al.
Published: (2010)
by: Koh, Choo Yan, et al.
Published: (2010)
Pomegranate juice induced cell cycle arrest and apoptosis through mitochondria pathway in human lung adenocarcinoma cells
by: Abdul Ghani, Radiah, et al.
Published: (2018)
by: Abdul Ghani, Radiah, et al.
Published: (2018)
Clausenidin induces caspase-dependent apoptosis in colon cancer
by: Waziri, Peter M., et al.
Published: (2016)
by: Waziri, Peter M., et al.
Published: (2016)
Selective apoptosis induction in MCF-7cell line by truncated minimal functional region of Apoptin
by: Lim, Shen Ni, et al.
Published: (2013)
by: Lim, Shen Ni, et al.
Published: (2013)
Inhibitory Effects Of Andrographolide In Pc-3 Cell Line And The Induction Of Apoptosis Via The Involvement Of Caspases 3, 8 And 9
by: Manimaran, Janany
Published: (2023)
by: Manimaran, Janany
Published: (2023)
Recent advances in apoptosis, mitochondria and drug resistance in cancer cells
by: Indran, I., et al.
Published: (2011)
by: Indran, I., et al.
Published: (2011)
Discovery of a highly active anticancer analogue of cardamonin that acts as an inducer of caspase-dependent apoptosis and modulator of the mTOR pathway
by: Khaled bin Break, Mohammed, et al.
Published: (2018)
by: Khaled bin Break, Mohammed, et al.
Published: (2018)
Cardamonin induces apoptosis in human nasopharyngeal carcinoma cells via mitochondrial death pathway mediated by caspase-3 and caspase-8 activation, independent of caspase-9 signalling responses
by: Chiang, Michelle
Published: (2016)
by: Chiang, Michelle
Published: (2016)
Caspases-3 and -7 are activated in goniothalamin-induced apoptosis in human Jurkat T-cells
by: Inayat-Hussain, Salmaan H., et al.
Published: (1999)
by: Inayat-Hussain, Salmaan H., et al.
Published: (1999)
Mitochondria: Redox metabolism and dysfunction
by: Kang, J., et al.
Published: (2012)
by: Kang, J., et al.
Published: (2012)
Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signalling pathways
by: Foo, Jhi Biau, et al.
Published: (2014)
by: Foo, Jhi Biau, et al.
Published: (2014)
Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signaling pathways
by: Foo, Jhi Biau, et al.
Published: (2014)
by: Foo, Jhi Biau, et al.
Published: (2014)
Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis
by: Treude, Fabian, et al.
Published: (2014)
by: Treude, Fabian, et al.
Published: (2014)
The Role Of Caspase-Activated Dnase (Cad) In Chromosome Breaks During Oxidative Stressinduced Apoptosis
by: Boon, Siaw Shi
Published: (2009)
by: Boon, Siaw Shi
Published: (2009)
Goniothalamin selectively induces apoptosis on human hepatoblastoma cells through caspase-3 activation.
by: Al-Qubaisi, Mothanna, et al.
Published: (2013)
by: Al-Qubaisi, Mothanna, et al.
Published: (2013)
Caspase-3 and caspase-8 expression in breast cancer: caspase-3 is associated with survival
by: Xuan, Pu, et al.
Published: (2016)
by: Xuan, Pu, et al.
Published: (2016)
Water extract of brewers' rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/β-catenin downstream signaling pathway in brewers' rice-treated rats with azoxymethane-induced colon carcinogenesis
by: Tan, Bee Ling, et al.
Published: (2015)
by: Tan, Bee Ling, et al.
Published: (2015)
Ficus auriculata (fig) extracts induced cell cycle profile changes and apoptosis through caspase-independent pathway in human LungAdenocarcinoma cell line, A549
by: Jamil, Elyna Fatini, et al.
Published: (2017)
by: Jamil, Elyna Fatini, et al.
Published: (2017)
A novel Osmium-based compound targets the mitochondria and triggers ROS-dependent apoptosis in colon carcinoma
by: Maillet, A., et al.
Published: (2013)
by: Maillet, A., et al.
Published: (2013)
Repressing the activity of protein kinase CK2 releases the brakes on mitochondria-mediated apoptosis in cancer cells
by: Hanif, I., et al.
Published: (2011)
by: Hanif, I., et al.
Published: (2011)
Characterisation of Pseudorabies Virus and Its Mutants
by: Allaudin, Zeenathul Nazariah
Published: (1999)
by: Allaudin, Zeenathul Nazariah
Published: (1999)
The shape shifter
by: Allaudin, Zeenathul Nazariah
Published: (2014)
by: Allaudin, Zeenathul Nazariah
Published: (2014)
Mechanisms of cisplatin-induced cell death in malignant mesothelioma cells: Role of inhibitor of apoptosis proteins (IAPs) and caspases
by: Cregan, I., et al.
Published: (2013)
by: Cregan, I., et al.
Published: (2013)
Palmitic acid of Musa Paradisiaca induces apoptosis through caspase-3 in human oral squamous cell carcinoma
by: Budi, H. S., et al.
Published: (2022)
by: Budi, H. S., et al.
Published: (2022)
The role of mitochondria and KATP channels in the vasodilatation response to simvastatin: comparison with the effects of simvastatin in pancreatic β-cells
by: Almukhtar, Hani Mhedi
Published: (2015)
by: Almukhtar, Hani Mhedi
Published: (2015)
The role of mitochondria in ageing
by: Pollard, Amelia K.
Published: (2017)
by: Pollard, Amelia K.
Published: (2017)
Curcumin Analog DK1 Induces Apoptosis in Human Osteosarcoma Cells In Vitro through Mitochondria-Dependent Signaling Pathway
by: Muhammad Nazirul Mubin, Aziz, et al.
Published: (2018)
by: Muhammad Nazirul Mubin, Aziz, et al.
Published: (2018)
DK1 Induces Apoptosis via Mitochondria-Dependent Signaling Pathway in Human Colon Carcinoma Cell Lines In Vitro
by: Yazmin, Hussin, et al.
Published: (2018)
by: Yazmin, Hussin, et al.
Published: (2018)
DK1 induces apoptosis via mitochondria-dependent signaling pathway in human colon carcinoma cell linesIn vitro
by: Hussin, Yazmin, et al.
Published: (2018)
by: Hussin, Yazmin, et al.
Published: (2018)
Curcumin analog DK1 induces apoptosis in human osteosarcoma cells in vitro through mitochondria-dependent signaling pathway
by: Aziz, Muhammad Nazirul Mubin, et al.
Published: (2018)
by: Aziz, Muhammad Nazirul Mubin, et al.
Published: (2018)
Koenimbin induces apoptosis in MCF7 breast cancer cells with antiproliferation effect on MCF7-derived cancer stem cell (CD44+/CD24-/low) in vitro / Fatemeh Ahmadipour
by: Fatemeh, Ahmadipour
Published: (2018)
by: Fatemeh, Ahmadipour
Published: (2018)
Similar Items
-
Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cells
by: Lim, Su Wen, et al.
Published: (2014) -
Zerumbone induces apoptosis in Jurkat T-cell line via activation of caspase 3 and caspase 9
by: Rahman, Heshu Sulaiman, et al.
Published: (2012) -
Acalypha wilkesiana ethyl acetate extract enhances the in vitro cytotoxic effects of α-tocopherol in human brain and lung cancer cells
by: Lim, Su Wen, et al.
Published: (2013) -
Acalypha wilkesiana extracts induce apoptosis by causing single strand and double strand DNA breaks
by: Lim, Su Wen, et al.
Published: (2011) -
Induction of apoptosis in MCF-7 cells via oxidative stress generation, mitochondria-dependent and caspase-independent pathway by ethyl acetate extract of Dillenia suffruticosa and its chemical profile
by: Tor, Yin Sim, et al.
Published: (2015)