Antioxidant and anti-ulcer effects of ethyl acetate fraction of Merremia tridentata (L.) Hallier f. root
The present study was aimed to determine the antioxidant and anti-ulcer effects of Merremia tridentata root (Arrow-leaf Morning Glory). Antioxidant potential of crude acetone extract and its fractions was evaluated by using various in vitro assays. In the anti-ulcer study, pre-treatment with ethyl a...
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| Format: | Article |
| Language: | English |
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Elsevier
2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/36491/ http://psasir.upm.edu.my/id/eprint/36491/1/Antioxidant%20and%20Anti-Ulcer%20Effects%20of%20Ethyl%20Acetate%20Fraction%20of.pdf |
| _version_ | 1848848347556741120 |
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| author | Sowndhararajan, Kandhasamy Chin, Nyuk Ling |
| author_facet | Sowndhararajan, Kandhasamy Chin, Nyuk Ling |
| author_sort | Sowndhararajan, Kandhasamy |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The present study was aimed to determine the antioxidant and anti-ulcer effects of Merremia tridentata root (Arrow-leaf Morning Glory). Antioxidant potential of crude acetone extract and its fractions was evaluated by using various in vitro assays. In the anti-ulcer study, pre-treatment with ethyl acetate fraction (MEF) (50, 100 and 200 mg/kg b.wt.) significantly protected the ethanol-induced gastric ulcer in rats. Simultaneously, the antioxidant enzyme levels of superoxide dismutase, catalase and glutathione in the stomach tissues were significantly increased while pre-treated with MEF. From the results, MEF has the therapeutical potential to prevent gastric ulceration induced by ethanol. |
| first_indexed | 2025-11-15T09:33:03Z |
| format | Article |
| id | upm-36491 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:33:03Z |
| publishDate | 2014 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-364912015-12-01T04:09:14Z http://psasir.upm.edu.my/id/eprint/36491/ Antioxidant and anti-ulcer effects of ethyl acetate fraction of Merremia tridentata (L.) Hallier f. root Sowndhararajan, Kandhasamy Chin, Nyuk Ling The present study was aimed to determine the antioxidant and anti-ulcer effects of Merremia tridentata root (Arrow-leaf Morning Glory). Antioxidant potential of crude acetone extract and its fractions was evaluated by using various in vitro assays. In the anti-ulcer study, pre-treatment with ethyl acetate fraction (MEF) (50, 100 and 200 mg/kg b.wt.) significantly protected the ethanol-induced gastric ulcer in rats. Simultaneously, the antioxidant enzyme levels of superoxide dismutase, catalase and glutathione in the stomach tissues were significantly increased while pre-treated with MEF. From the results, MEF has the therapeutical potential to prevent gastric ulceration induced by ethanol. Elsevier 2014 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/36491/1/Antioxidant%20and%20Anti-Ulcer%20Effects%20of%20Ethyl%20Acetate%20Fraction%20of.pdf Sowndhararajan, Kandhasamy and Chin, Nyuk Ling (2014) Antioxidant and anti-ulcer effects of ethyl acetate fraction of Merremia tridentata (L.) Hallier f. root. Agriculture and Agricultural Science Procedia, 2. pp. 406-414. ISSN 2210-7843 10.1016/j.aaspro.2014.11.057 |
| spellingShingle | Sowndhararajan, Kandhasamy Chin, Nyuk Ling Antioxidant and anti-ulcer effects of ethyl acetate fraction of Merremia tridentata (L.) Hallier f. root |
| title | Antioxidant and anti-ulcer effects of ethyl acetate fraction of Merremia tridentata (L.) Hallier f. root |
| title_full | Antioxidant and anti-ulcer effects of ethyl acetate fraction of Merremia tridentata (L.) Hallier f. root |
| title_fullStr | Antioxidant and anti-ulcer effects of ethyl acetate fraction of Merremia tridentata (L.) Hallier f. root |
| title_full_unstemmed | Antioxidant and anti-ulcer effects of ethyl acetate fraction of Merremia tridentata (L.) Hallier f. root |
| title_short | Antioxidant and anti-ulcer effects of ethyl acetate fraction of Merremia tridentata (L.) Hallier f. root |
| title_sort | antioxidant and anti-ulcer effects of ethyl acetate fraction of merremia tridentata (l.) hallier f. root |
| url | http://psasir.upm.edu.my/id/eprint/36491/ http://psasir.upm.edu.my/id/eprint/36491/ http://psasir.upm.edu.my/id/eprint/36491/1/Antioxidant%20and%20Anti-Ulcer%20Effects%20of%20Ethyl%20Acetate%20Fraction%20of.pdf |