Antiartherosclerotic effects of plant flavonoids

Atherosclerosis is the process of hardening and narrowing the arteries. Atherosclerosis is generally associated with cardiovascular diseases such as strokes, heart attacks, and peripheral vascular diseases. Since the usage of the synthetic drug, statins, leads to various side effects, the plants fla...

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Main Authors: Salvamani, Shamala, Gunasekaran, Baskaran, Shaharuddin, Noor Azmi, Ahmad, Siti Aqlima, Shukor, Mohd Yunus
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:http://psasir.upm.edu.my/id/eprint/36465/
http://psasir.upm.edu.my/id/eprint/36465/1/36465.pdf
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author Salvamani, Shamala
Gunasekaran, Baskaran
Shaharuddin, Noor Azmi
Ahmad, Siti Aqlima
Shukor, Mohd Yunus
author_facet Salvamani, Shamala
Gunasekaran, Baskaran
Shaharuddin, Noor Azmi
Ahmad, Siti Aqlima
Shukor, Mohd Yunus
author_sort Salvamani, Shamala
building UPM Institutional Repository
collection Online Access
description Atherosclerosis is the process of hardening and narrowing the arteries. Atherosclerosis is generally associated with cardiovascular diseases such as strokes, heart attacks, and peripheral vascular diseases. Since the usage of the synthetic drug, statins, leads to various side effects, the plants flavonoids with antiartherosclerotic activity gained much attention and were proven to reduce the risk of atherosclerosis in vitro and in vivo based on different animal models. The flavonoids compounds also exhibit lipid lowering effects and anti-inflammatory and antiatherogenic properties. The future development of flavonoids-based drugs is believed to provide significant effects on atherosclerosis and its related diseases. This paper discusses the antiatherosclerotic effects of selected plant flavonoids such as quercetin, kaempferol, myricetin, rutin, naringenin, catechin, fisetin, and gossypetin.
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institution Universiti Putra Malaysia
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publishDate 2014
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spelling upm-364652015-12-15T03:41:41Z http://psasir.upm.edu.my/id/eprint/36465/ Antiartherosclerotic effects of plant flavonoids Salvamani, Shamala Gunasekaran, Baskaran Shaharuddin, Noor Azmi Ahmad, Siti Aqlima Shukor, Mohd Yunus Atherosclerosis is the process of hardening and narrowing the arteries. Atherosclerosis is generally associated with cardiovascular diseases such as strokes, heart attacks, and peripheral vascular diseases. Since the usage of the synthetic drug, statins, leads to various side effects, the plants flavonoids with antiartherosclerotic activity gained much attention and were proven to reduce the risk of atherosclerosis in vitro and in vivo based on different animal models. The flavonoids compounds also exhibit lipid lowering effects and anti-inflammatory and antiatherogenic properties. The future development of flavonoids-based drugs is believed to provide significant effects on atherosclerosis and its related diseases. This paper discusses the antiatherosclerotic effects of selected plant flavonoids such as quercetin, kaempferol, myricetin, rutin, naringenin, catechin, fisetin, and gossypetin. Hindawi Publishing Corporation 2014 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/36465/1/36465.pdf Salvamani, Shamala and Gunasekaran, Baskaran and Shaharuddin, Noor Azmi and Ahmad, Siti Aqlima and Shukor, Mohd Yunus (2014) Antiartherosclerotic effects of plant flavonoids. BioMed Research International, 2014. art. no. 480258. pp. 1-11. ISSN 2314-6133; ESSN: 2314-6141 http://www.hindawi.com/journals/bmri/2014/480258/abs/ 10.1155/2014/480258
spellingShingle Salvamani, Shamala
Gunasekaran, Baskaran
Shaharuddin, Noor Azmi
Ahmad, Siti Aqlima
Shukor, Mohd Yunus
Antiartherosclerotic effects of plant flavonoids
title Antiartherosclerotic effects of plant flavonoids
title_full Antiartherosclerotic effects of plant flavonoids
title_fullStr Antiartherosclerotic effects of plant flavonoids
title_full_unstemmed Antiartherosclerotic effects of plant flavonoids
title_short Antiartherosclerotic effects of plant flavonoids
title_sort antiartherosclerotic effects of plant flavonoids
url http://psasir.upm.edu.my/id/eprint/36465/
http://psasir.upm.edu.my/id/eprint/36465/
http://psasir.upm.edu.my/id/eprint/36465/
http://psasir.upm.edu.my/id/eprint/36465/1/36465.pdf