Analgesic efficacy of pre-operative tramadol in combination with acepromazine in cats undergoing ovariohysterectomy
In a randomized blind trial, cats undergoing ovariohysterectomy were premedicated subcutaneously with 4 mg/kg tramadol and 0.1 mg/kg acepromazine (Group AT4); 2 mg/kg tramadol and 0.1 mg/kg acepromazine (Group AT2); or 0.1 mg/kg acepromazine (Group ACE). Composite pain scores (CPS), and mechanical t...
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| Format: | Article |
| Language: | English |
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Faculty of Veterinary Science, University of Agriculture, Faisalabad
2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/36440/ http://psasir.upm.edu.my/id/eprint/36440/1/Analgesic%20efficacy%20of%20pre.pdf |
| _version_ | 1848848332866191360 |
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| author | Basiri, Bita Chen, Hui Cheng Rahman, Nor Alimah |
| author_facet | Basiri, Bita Chen, Hui Cheng Rahman, Nor Alimah |
| author_sort | Basiri, Bita |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | In a randomized blind trial, cats undergoing ovariohysterectomy were premedicated subcutaneously with 4 mg/kg tramadol and 0.1 mg/kg acepromazine (Group AT4); 2 mg/kg tramadol and 0.1 mg/kg acepromazine (Group AT2); or 0.1 mg/kg acepromazine (Group ACE). Composite pain scores (CPS), and mechanical thresholds at metatarsal pad (MTp) and surgical site (MTs) were determined at -0.5, 0.5, 2.5, 3.5, 4.5, 6.5, 8.5, 10.5, 12.5, 12 and 48 hours after pre-medication. Post-operatively, CPS was the highest in ACE and all cats required rescue analgesia. None of the cats in AT4 or AT2 needed rescue analgesia. Group AT4 has lower CPS and higher MTp compared to AT2. Decrement of MTs tended to be the least in AT4. This study shows that tramadol at 4 mg/kg provided more profound and longer duration of analgesic effect than 2 mg/kg, when combined with acepromazine for premedication in cats. |
| first_indexed | 2025-11-15T09:32:49Z |
| format | Article |
| id | upm-36440 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:32:49Z |
| publishDate | 2014 |
| publisher | Faculty of Veterinary Science, University of Agriculture, Faisalabad |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-364402015-08-21T02:51:58Z http://psasir.upm.edu.my/id/eprint/36440/ Analgesic efficacy of pre-operative tramadol in combination with acepromazine in cats undergoing ovariohysterectomy Basiri, Bita Chen, Hui Cheng Rahman, Nor Alimah In a randomized blind trial, cats undergoing ovariohysterectomy were premedicated subcutaneously with 4 mg/kg tramadol and 0.1 mg/kg acepromazine (Group AT4); 2 mg/kg tramadol and 0.1 mg/kg acepromazine (Group AT2); or 0.1 mg/kg acepromazine (Group ACE). Composite pain scores (CPS), and mechanical thresholds at metatarsal pad (MTp) and surgical site (MTs) were determined at -0.5, 0.5, 2.5, 3.5, 4.5, 6.5, 8.5, 10.5, 12.5, 12 and 48 hours after pre-medication. Post-operatively, CPS was the highest in ACE and all cats required rescue analgesia. None of the cats in AT4 or AT2 needed rescue analgesia. Group AT4 has lower CPS and higher MTp compared to AT2. Decrement of MTs tended to be the least in AT4. This study shows that tramadol at 4 mg/kg provided more profound and longer duration of analgesic effect than 2 mg/kg, when combined with acepromazine for premedication in cats. Faculty of Veterinary Science, University of Agriculture, Faisalabad 2014 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/36440/1/Analgesic%20efficacy%20of%20pre.pdf Basiri, Bita and Chen, Hui Cheng and Rahman, Nor Alimah (2014) Analgesic efficacy of pre-operative tramadol in combination with acepromazine in cats undergoing ovariohysterectomy. Pakistan Veterinary Journal, 34 (3). pp. 403-405. ISSN 0253-8318; ESSN: 2074-7764 http://www.pvj.com.pk/archive/Volume_34_Issue_3_2014.htm |
| spellingShingle | Basiri, Bita Chen, Hui Cheng Rahman, Nor Alimah Analgesic efficacy of pre-operative tramadol in combination with acepromazine in cats undergoing ovariohysterectomy |
| title | Analgesic efficacy of pre-operative tramadol in combination with acepromazine in cats undergoing ovariohysterectomy |
| title_full | Analgesic efficacy of pre-operative tramadol in combination with acepromazine in cats undergoing ovariohysterectomy |
| title_fullStr | Analgesic efficacy of pre-operative tramadol in combination with acepromazine in cats undergoing ovariohysterectomy |
| title_full_unstemmed | Analgesic efficacy of pre-operative tramadol in combination with acepromazine in cats undergoing ovariohysterectomy |
| title_short | Analgesic efficacy of pre-operative tramadol in combination with acepromazine in cats undergoing ovariohysterectomy |
| title_sort | analgesic efficacy of pre-operative tramadol in combination with acepromazine in cats undergoing ovariohysterectomy |
| url | http://psasir.upm.edu.my/id/eprint/36440/ http://psasir.upm.edu.my/id/eprint/36440/ http://psasir.upm.edu.my/id/eprint/36440/1/Analgesic%20efficacy%20of%20pre.pdf |