Acute toxicity study of zerumbone-loaded nanostructured lipid carrier on BALB/c mice model

QR Code

Acute toxicity study of zerumbone-loaded nanostructured lipid carrier on BALB/c mice model

Zerumbone- (ZER-) loaded nanostructure lipid carrier (NLC) (ZER-NLC) prepared for its antileukemia effect in vitro was evaluated for its toxicological effects by observing changes in the liver, kidney, spleen, lung, heart, and brain tissues, serum biochemical parameters, total haemogram, and bone ma...

Full description

Bibliographic Details
Main Authors:	Rahman, Heshu Sulaiman, Abdullah, Rasedee, Othman, Hemn Hassan, Chartrand, Max Stanley, Namvar, Farideh, Yeap, Swee Keong, Abdul Samad, Nozlena, Andas, Reena Joys, Muhammad Nadzri, Nabilah, Anasamy, Theebaa, Ng, Kuan Beng, How, Chee Wun
Format:	Article
Language:	English
Published:	Hindawi Publishing Corporation 2014
Online Access:	http://psasir.upm.edu.my/id/eprint/36326/ http://psasir.upm.edu.my/id/eprint/36326/1/Acute%20toxicity%20study%20of%20zerumbone.pdf

Similar Items

Antiproliferative Efficacy of Zerumbone-Loaded Nanostructured Lipid Carrier in BALB/C Mice Model of Breast Cancer
by: Rahman, Heshu Sulaiman, et al.
Published: (2014)

In vivo assessment of nanostructured lipid carrier for oral delivery of zerumbone in leukemic mice model
by: Rahman, Heshu Sulaiman, et al.
Published: (2014)

Zerumbone induces G2/M cell cycle arrest and apoptosis via mitochondrial pathway in Jurkat cell line
by: Rahman, Heshu Sulaiman, et al.
Published: (2014)

Biomedical properties of a natural dietary plant metabolite, zerumbone, in cancer therapy and chemoprevention trials
by: Rahman, Heshu Sulaiman, et al.
Published: (2014)

Biomedical properties of a natural dietary plant metabolite, zerumbone, in cancer therapy and chemoprevention trail
by: Rahman, Heshu Sulaiman, et al.
Published: (2014)

Antileukemic effect of zerumbone-loaded nanostructured lipid carrier in WEHI-3B cell-induced murine leukemia model
by: Rahman, Heshu Sulaiman, et al.
Published: (2015)

Zerumbone-loaded nanostructured lipid carriers: preparation, characterization, and antileukemic effect
by: Rahman, Heshu Sulaiman, et al.
Published: (2013)

Zerumbone-loaded nanostructured lipid carrier induces apoptosis of canine mammary Adenocarcinoma cells
by: Foong, Jia Ning, et al.
Published: (2018)

Antihypercholesterolemic and antioxidant efficacies of zerumbone on the formation, development, and establishment of atherosclerosis in cholesterol-fed rabbits
by: Othman, Hemn Hassan, et al.
Published: (2015)

Zerumbone-loaded nanostructured lipid carrier induces G2/M cell cycle arrest and apoptosis via mitochondrial pathway in a human lymphoblastic leukemia cell line
by: Rahman, Heshu Sulaiman, et al.
Published: (2014)

Zerumbone induces apoptosis in human acute leukemia Jurkat T-cell line
by: Rahman, Heshu Sulaiman, et al.
Published: (2012)

Cytotoxicty of zerumbone against liver cancer cell lines (HepG2) via apoptosis activity
by: Abdul Samad, Nozlena, et al.
Published: (2014)

Zerumbone nanoparticle preparation and characterization
by: Rahman, Heshu, et al.
Published: (2015)

Zerumbone-loaded nanostructured lipid carrier gel enhances wound healing in diabetic rats
by: Albaayit, Shaymaa Fadhel Abbas, et al.
Published: (2022)

Zerumbone induces apoptosis in Jurkat T-cell line via activation of caspase 3 and caspase 9
by: Rahman, Heshu Sulaiman, et al.
Published: (2012)

Induction of apoptosis by cis-3-(3',4'-dimethoxyphenyl)-4-[(E)-3"',4"'-dimethoxystyryl]cyclohex-1-ene isolated from the rhizome of Zingiber cassumunar roxb. on human T-lymphoblastic leukemia cell line, CEMss
by: Anasamy, Theebaa
Published: (2013)

Apoptosis induction in human leukemia cell lines by gold nanoparticles synthesized using the green biosynthetic approach
by: Namvar, Farideh, et al.
Published: (2015)

Cytotoxic effects of bio-synthesized zinc oxide nanoparticles on murine cell lines
by: Namvar, Farideh, et al.
Published: (2014)

Combination of zerumbone and cisplatin to treat cervical intraepithelial neoplasia in female BALB/c mice.
by: Abdul, Ahmad Bustamam, et al.
Published: (2009)

Effects Of Zerumbone From Zingiber Zerumbet On Cervicalcancer-Induced Female Balb/C Mice
by: Devi Tailan, Nirmala
Published: (2007)

Cytotoxic effect of magnetic iron oxide nanoparticles synthesized via seaweed aqueous extract
by: Namvar, Farideh, et al.
Published: (2014)

Attenuation of atherosclerosis by zerumbone in hypercholesterolaemic rabbits
by: Othman, Hemn Hassan, et al.
Published: (2012)

Zerumbone-loaded nanostructured lipid carrier induces apoptosis in human colorectal adenocarcinoma (Caco2) cell line
by: Nathaniel, Christian, et al.
Published: (2016)

Physicochemical properties of nanostructured lipid carriers as colloidal carrier system stabilized with polysorbate 20 and polysorbate 80
by: How, Chee Wun, et al.
Published: (2011)

Restriction Digest And Electrophoretic Analysis Of Mitochondrial Genome From Jamnapari Goats
by: A. Reenaa, Joys Andas.
Published: (2010)

Characterization and toxicity of citral incorporated with nanostructured lipid carrier
by: Mohammed Alitheen, Noorjahan Banu, et al.
Published: (2018)

Effect of Zerumbone-loaded nanostructured lipid carrier on canine mammary gland tumour cell line
by: Foong, Jia Ning
Published: (2015)

Isolation, purification and evaluation of anticancer principle from Zingiber zerumbet
by: Rahman, Heshu Sulaiman, et al.
Published: (2014)

Acute and sub-acute toxicity profile of thymoquinone-loaded nanostructured lipid carrier (TQNLC) in BALB/c mice
by: Yong, Sze Ong, et al.
Published: (2016)

Anti-angiogenic and anti-hepatocellular carcinoma properties of zerumbone extracted from Zingiber Zerumbet (l.) Smith
by: Abdul Samad, Nozlena
Published: (2015)

Characterization and cytotoxicty of nanostructured lipid carriers formulated with olive oil, hydrogenated palm oil and polysorbate 80.
by: How, Chee Wun, et al.
Published: (2013)

A phenylbutenoid dimer, cis-3-(3′,4′-dimethoxyphenyl)-4-[(E)-3′′′,4′′′-dimethoxystyryl] cyclohex-1-ene, exhibits apoptogenic properties in T-acute lymphoblastic leukemia cells via induction of p53-independent mitochondrial signalling pathway
by: Anasamy, Theebaa, et al.
Published: (2013)

Thymoquinone loaded nanostructured lipid carriers (TQ-NLC) and uses thereof
by: Saiful Yazan, Latifah, et al.
Published: (2012)

Prophylactic and therapeutic efficacies of dietary zerumbone supplementation on the pathogenesis of atherosclerosis in cholesterol-fed rabbits
by: Hassan, Hemn Hassan Othman
Published: (2014)

An overview of in vitro, in vivo, and computational techniques for cancer-associated angiogenesis studies
by: Rahman, Heshu Sulaiman, et al.
Published: (2020)

Tamoxifen-loaded nanostructured lipid carrier as a drug delivery system: characterization, stability assessment and cytotoxicity
by: How, Chee Wun, et al.
Published: (2013)

Cytotoxicity and mechanisms of action of Zerumbone-loaded nanostructured lipid carrier in triple negative breast cancer cells, MDA-MB-231
by: Hosseinpour, Mahnaz
Published: (2015)

In vitro cytotoxicity and anticancer effects of citral nanostructured lipid carrier on MDA MBA-231 human breast cancer cells
by: Nordin, Noraini, et al.
Published: (2019)

Antitumour Promoting Activity And Mode Of Action Of Methanolic Extracts Of Selected Malaysian Seaweeds And Oil Palm Fronds
by: Namvar, Farideh
Published: (2009)

Characterization and stability of nanostructured lipid carriers as drug delivery system
by: Abbasalipourkabirreh, Roghayeh, et al.
Published: (2012)