Acute drug reaction and non-compliance to anti-tuberculosis medications: a case study
Introduction: Tuberculosis (TB) is a significant re-emerging disease in Malaysia. TB treatment involves prolonged use of antibiotics, but adverse drug reaction and non-compliance to anti- tuberculosis drugs hamper the success of treatment. Case report: A 59 year old man with underlying diabetes an...
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| Format: | Article |
| Language: | English |
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Community Health Society Malaysia
2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/36320/ http://psasir.upm.edu.my/id/eprint/36320/1/Acute%20drug%20reaction%20and%20non-compliance%20to%20anti-tuberculosis%20medications%20a%20case%20study.pdf |
| _version_ | 1848848299134550016 |
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| author | Mahmud, Aidalina Mohd Shah, Ashwinni Rajandran, Darsayini Yusof, Khalida |
| author_facet | Mahmud, Aidalina Mohd Shah, Ashwinni Rajandran, Darsayini Yusof, Khalida |
| author_sort | Mahmud, Aidalina |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Introduction: Tuberculosis (TB) is a significant re-emerging disease in Malaysia. TB treatment involves prolonged use of antibiotics, but adverse drug reaction and non-compliance to anti- tuberculosis drugs hamper the success of treatment.
Case report: A 59 year old man with underlying diabetes and hyperlipidaemia presented with a four-day history of vomiting and diarrhoea. He was diagnosed with smear negative pulmonary TB three weeks earlier and was on TB medications. Apart from reduced air entry at both lung apices, the physical examination was normal. All blood results were normal except mild derangement of the renal profile and raised monocyte count. The patient had poor knowledge, insight and attitude towards his illness.
Conclusion: We report a case of acute drug reaction and non-compliance to anti-TB, and the possible associated factors. Knowledge, insight and proper attitude are vital in ensuring the patient’s treatment compliance. |
| first_indexed | 2025-11-15T09:32:17Z |
| format | Article |
| id | upm-36320 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:32:17Z |
| publishDate | 2014 |
| publisher | Community Health Society Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-363202020-07-06T03:05:43Z http://psasir.upm.edu.my/id/eprint/36320/ Acute drug reaction and non-compliance to anti-tuberculosis medications: a case study Mahmud, Aidalina Mohd Shah, Ashwinni Rajandran, Darsayini Yusof, Khalida Introduction: Tuberculosis (TB) is a significant re-emerging disease in Malaysia. TB treatment involves prolonged use of antibiotics, but adverse drug reaction and non-compliance to anti- tuberculosis drugs hamper the success of treatment. Case report: A 59 year old man with underlying diabetes and hyperlipidaemia presented with a four-day history of vomiting and diarrhoea. He was diagnosed with smear negative pulmonary TB three weeks earlier and was on TB medications. Apart from reduced air entry at both lung apices, the physical examination was normal. All blood results were normal except mild derangement of the renal profile and raised monocyte count. The patient had poor knowledge, insight and attitude towards his illness. Conclusion: We report a case of acute drug reaction and non-compliance to anti-TB, and the possible associated factors. Knowledge, insight and proper attitude are vital in ensuring the patient’s treatment compliance. Community Health Society Malaysia 2014 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/36320/1/Acute%20drug%20reaction%20and%20non-compliance%20to%20anti-tuberculosis%20medications%20a%20case%20study.pdf Mahmud, Aidalina and Mohd Shah, Ashwinni and Rajandran, Darsayini and Yusof, Khalida (2014) Acute drug reaction and non-compliance to anti-tuberculosis medications: a case study. International Journal of Public Health and Clinical Sciences, 1 (1). pp. 220-229. ISSN 2289-7577 http://publichealthmy.org/ejournal/ojs2/index.php/ijphcs/article/view/93 |
| spellingShingle | Mahmud, Aidalina Mohd Shah, Ashwinni Rajandran, Darsayini Yusof, Khalida Acute drug reaction and non-compliance to anti-tuberculosis medications: a case study |
| title | Acute drug reaction and non-compliance to anti-tuberculosis medications: a case study |
| title_full | Acute drug reaction and non-compliance to anti-tuberculosis medications: a case study |
| title_fullStr | Acute drug reaction and non-compliance to anti-tuberculosis medications: a case study |
| title_full_unstemmed | Acute drug reaction and non-compliance to anti-tuberculosis medications: a case study |
| title_short | Acute drug reaction and non-compliance to anti-tuberculosis medications: a case study |
| title_sort | acute drug reaction and non-compliance to anti-tuberculosis medications: a case study |
| url | http://psasir.upm.edu.my/id/eprint/36320/ http://psasir.upm.edu.my/id/eprint/36320/ http://psasir.upm.edu.my/id/eprint/36320/1/Acute%20drug%20reaction%20and%20non-compliance%20to%20anti-tuberculosis%20medications%20a%20case%20study.pdf |