A three-dimensional collagen construct to model lipopolysaccharide-induced activation of BV2 microglia
Background: We report a novel method of culturing microglia in three dimension (3D) using collagen as a substrate. By culturing microglia within a matrix, we aim to emulate the physical state of microglia embedded within parenchyma. Methods: BV2 microglia cell suspensions were prepared with type I c...
| Main Authors: | Haw, Randy Tatt Yhew, Tong, Chih Kong, Yew, Andrew, Lee, Han Chung, Phillips, James B., Vidyadaran, Sharmili |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BioMed Central
2014
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/36302/ http://psasir.upm.edu.my/id/eprint/36302/1/A%20three.pdf |
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