A report of three cases of untreated Graves’ disease associated with pancytopenia in Malaysia
Generally, clinical presentations of Graves’ disease range from asymptomatic disease to overt symptomatic hyperthyroidism with heat intolerance, tremor, palpitation, weight loss, and increased appetite. However, atypical presentation of Graves’ disease with hematological system involvement, notably...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Electronic Physician
2014
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/36252/ http://psasir.upm.edu.my/id/eprint/36252/1/A%20report%20of%20three%20cases%20of%20untreated%20Graves.pdf |
| _version_ | 1848848280333582336 |
|---|---|
| author | Rafhati, Abdullah Noor Chee, Keong See Hoo, Fan Kee Mohamed Badrulnizam, Long Bidin |
| author_facet | Rafhati, Abdullah Noor Chee, Keong See Hoo, Fan Kee Mohamed Badrulnizam, Long Bidin |
| author_sort | Rafhati, Abdullah Noor |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Generally, clinical presentations of Graves’ disease range from asymptomatic disease to overt symptomatic hyperthyroidism with heat intolerance, tremor, palpitation, weight loss, and increased appetite. However, atypical presentation of Graves’ disease with hematological system involvement, notably pancytopenia, is distinctly uncommon. Hereby, we present and discuss a series of three untreated cases of Graves’ disease clinically presented with pancytopenia and the hematological abnormalities that responded well to anti-thyroid treatment. With resolution of the thyrotoxic state, the hematological parameters improved simultaneously. Thus, it is crucial that anti-thyroid treatment be considered in patients with Graves’ disease and pancytopenia after a thorough hematological evaluation. |
| first_indexed | 2025-11-15T09:31:59Z |
| format | Article |
| id | upm-36252 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:31:59Z |
| publishDate | 2014 |
| publisher | Electronic Physician |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-362522015-10-29T06:15:24Z http://psasir.upm.edu.my/id/eprint/36252/ A report of three cases of untreated Graves’ disease associated with pancytopenia in Malaysia Rafhati, Abdullah Noor Chee, Keong See Hoo, Fan Kee Mohamed Badrulnizam, Long Bidin Generally, clinical presentations of Graves’ disease range from asymptomatic disease to overt symptomatic hyperthyroidism with heat intolerance, tremor, palpitation, weight loss, and increased appetite. However, atypical presentation of Graves’ disease with hematological system involvement, notably pancytopenia, is distinctly uncommon. Hereby, we present and discuss a series of three untreated cases of Graves’ disease clinically presented with pancytopenia and the hematological abnormalities that responded well to anti-thyroid treatment. With resolution of the thyrotoxic state, the hematological parameters improved simultaneously. Thus, it is crucial that anti-thyroid treatment be considered in patients with Graves’ disease and pancytopenia after a thorough hematological evaluation. Electronic Physician 2014-07 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/36252/1/A%20report%20of%20three%20cases%20of%20untreated%20Graves.pdf Rafhati, Abdullah Noor and Chee, Keong See and Hoo, Fan Kee and Mohamed Badrulnizam, Long Bidin (2014) A report of three cases of untreated Graves’ disease associated with pancytopenia in Malaysia. Electronic Physician, 6 (3). pp. 877-882. ISSN 2008-5842 http://www.ephysician.ir/index.php/browse-issues/year-2014-volume-6/year-2014-volume-6-issue-3/126-a-report-of-three-cases-of-untreated-graves-disease-associated-with-pancytopenia-in-malaysia |
| spellingShingle | Rafhati, Abdullah Noor Chee, Keong See Hoo, Fan Kee Mohamed Badrulnizam, Long Bidin A report of three cases of untreated Graves’ disease associated with pancytopenia in Malaysia |
| title | A report of three cases of untreated Graves’ disease associated with pancytopenia in Malaysia |
| title_full | A report of three cases of untreated Graves’ disease associated with pancytopenia in Malaysia |
| title_fullStr | A report of three cases of untreated Graves’ disease associated with pancytopenia in Malaysia |
| title_full_unstemmed | A report of three cases of untreated Graves’ disease associated with pancytopenia in Malaysia |
| title_short | A report of three cases of untreated Graves’ disease associated with pancytopenia in Malaysia |
| title_sort | report of three cases of untreated graves’ disease associated with pancytopenia in malaysia |
| url | http://psasir.upm.edu.my/id/eprint/36252/ http://psasir.upm.edu.my/id/eprint/36252/ http://psasir.upm.edu.my/id/eprint/36252/1/A%20report%20of%20three%20cases%20of%20untreated%20Graves.pdf |