Variation of microwave dielectric properties in the glucose biosensor system

Glucose biosensor is generally based on the reaction between glucose and glucose oxidase, which produces gluconic acid and hydrogen peroxide. The gluconic acid is a conductive material, while hydrogen peroxide has polar molecules. This article examines the changes of dielectric properties due to the...

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Main Authors: Jafari, Fariba, Khalid, Kaida, Hassan, Jumiah, Abbas, Zulkifly, Md Salim, Nora Salina
Format: Article
Language:English
Published: Taylor & Francis 2015
Online Access:http://psasir.upm.edu.my/id/eprint/35974/
http://psasir.upm.edu.my/id/eprint/35974/1/Variation%20of%20microwave%20dielectric%20properties%20in%20the%20glucose%20biosensor%20system.pdf
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author Jafari, Fariba
Khalid, Kaida
Hassan, Jumiah
Abbas, Zulkifly
Md Salim, Nora Salina
author_facet Jafari, Fariba
Khalid, Kaida
Hassan, Jumiah
Abbas, Zulkifly
Md Salim, Nora Salina
author_sort Jafari, Fariba
building UPM Institutional Repository
collection Online Access
description Glucose biosensor is generally based on the reaction between glucose and glucose oxidase, which produces gluconic acid and hydrogen peroxide. The gluconic acid is a conductive material, while hydrogen peroxide has polar molecules. This article examines the changes of dielectric properties due to the conductive loss below 2 GHz and dipole orientation of above that frequency of this reaction. The difference between the dielectric loss of glucose solution and the dielectric loss of glucose-enzyme reaction can be related to the glucose concentration in the samples, such as orange juice, black grape juice, sugarcane juice, and sapodilla juice. A good sensitivity to these differences due to the effect of ionic conductivity and dipole orientation was found at 1 and 16.44 GHz, respectively. The minimum detection limit of glucose concentration in the proposed technique was about 0.01 M (0.20 g/100 ml) with an optimum reaction ratio of about 1:1 between the enzyme solution and the glucose solution. This technique could benefit the future development of microwave biosensor by which both ionic conductivity and dipole effects can be considered simultaneously.
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spelling upm-359742017-09-08T02:38:32Z http://psasir.upm.edu.my/id/eprint/35974/ Variation of microwave dielectric properties in the glucose biosensor system Jafari, Fariba Khalid, Kaida Hassan, Jumiah Abbas, Zulkifly Md Salim, Nora Salina Glucose biosensor is generally based on the reaction between glucose and glucose oxidase, which produces gluconic acid and hydrogen peroxide. The gluconic acid is a conductive material, while hydrogen peroxide has polar molecules. This article examines the changes of dielectric properties due to the conductive loss below 2 GHz and dipole orientation of above that frequency of this reaction. The difference between the dielectric loss of glucose solution and the dielectric loss of glucose-enzyme reaction can be related to the glucose concentration in the samples, such as orange juice, black grape juice, sugarcane juice, and sapodilla juice. A good sensitivity to these differences due to the effect of ionic conductivity and dipole orientation was found at 1 and 16.44 GHz, respectively. The minimum detection limit of glucose concentration in the proposed technique was about 0.01 M (0.20 g/100 ml) with an optimum reaction ratio of about 1:1 between the enzyme solution and the glucose solution. This technique could benefit the future development of microwave biosensor by which both ionic conductivity and dipole effects can be considered simultaneously. Taylor & Francis 2015 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/35974/1/Variation%20of%20microwave%20dielectric%20properties%20in%20the%20glucose%20biosensor%20system.pdf Jafari, Fariba and Khalid, Kaida and Hassan, Jumiah and Abbas, Zulkifly and Md Salim, Nora Salina (2015) Variation of microwave dielectric properties in the glucose biosensor system. International Journal of Food Properties, 18 (7). pp. 1428-1433. ISSN 1094-2912; ESSN: 1532-2386 http://www.tandfonline.com/doi/abs/10.1080/10942912.2011.619293 10.1080/10942912.2011.619293
spellingShingle Jafari, Fariba
Khalid, Kaida
Hassan, Jumiah
Abbas, Zulkifly
Md Salim, Nora Salina
Variation of microwave dielectric properties in the glucose biosensor system
title Variation of microwave dielectric properties in the glucose biosensor system
title_full Variation of microwave dielectric properties in the glucose biosensor system
title_fullStr Variation of microwave dielectric properties in the glucose biosensor system
title_full_unstemmed Variation of microwave dielectric properties in the glucose biosensor system
title_short Variation of microwave dielectric properties in the glucose biosensor system
title_sort variation of microwave dielectric properties in the glucose biosensor system
url http://psasir.upm.edu.my/id/eprint/35974/
http://psasir.upm.edu.my/id/eprint/35974/
http://psasir.upm.edu.my/id/eprint/35974/
http://psasir.upm.edu.my/id/eprint/35974/1/Variation%20of%20microwave%20dielectric%20properties%20in%20the%20glucose%20biosensor%20system.pdf