Validation of a HPLC method for determination of hydroxymethylfurfural in crude palm oil

For the first time 5-hydroxymethyl-2-furaldehyde (HMF) was separated from crude palm oil (CPO), and its authenticity was determined using an RP-HPLC method. Separation was accomplished with isocratic elution of a mobile phase comprising water and methanol (92:8 v/v) on a Purospher Star RP-18e column...

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Main Authors: Ariffin, Abdul Azis, Mohd Ghazali, Hasanah, Kavousi, Parviz
Format: Article
Published: Elsevier 2014
Online Access:http://psasir.upm.edu.my/id/eprint/35957/
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author Ariffin, Abdul Azis
Mohd Ghazali, Hasanah
Kavousi, Parviz
author_facet Ariffin, Abdul Azis
Mohd Ghazali, Hasanah
Kavousi, Parviz
author_sort Ariffin, Abdul Azis
building UPM Institutional Repository
collection Online Access
description For the first time 5-hydroxymethyl-2-furaldehyde (HMF) was separated from crude palm oil (CPO), and its authenticity was determined using an RP-HPLC method. Separation was accomplished with isocratic elution of a mobile phase comprising water and methanol (92:8 v/v) on a Purospher Star RP-18e column (250 mm × 4.6 mm, 5.0 μm). The flow rate was adjusted to 1 ml/min and detection was performed at 284 nm. The method was validated, and results obtained exhibit a good recovery (95.58% to 98.39%). Assessment of precision showed that the relative standard deviations (RSD%) of retention times and peak areas of spiked samples were less than 0.59% and 2.66%, respectively. Further, the limit of detection (LOD) and LOQ were 0.02, 0.05 mg/kg, respectively, and the response was linear across the applied ranges. The crude palm oil samples analysed exhibited HMF content less than 2.27 mg/kg.
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spelling upm-359572016-02-12T02:37:49Z http://psasir.upm.edu.my/id/eprint/35957/ Validation of a HPLC method for determination of hydroxymethylfurfural in crude palm oil Ariffin, Abdul Azis Mohd Ghazali, Hasanah Kavousi, Parviz For the first time 5-hydroxymethyl-2-furaldehyde (HMF) was separated from crude palm oil (CPO), and its authenticity was determined using an RP-HPLC method. Separation was accomplished with isocratic elution of a mobile phase comprising water and methanol (92:8 v/v) on a Purospher Star RP-18e column (250 mm × 4.6 mm, 5.0 μm). The flow rate was adjusted to 1 ml/min and detection was performed at 284 nm. The method was validated, and results obtained exhibit a good recovery (95.58% to 98.39%). Assessment of precision showed that the relative standard deviations (RSD%) of retention times and peak areas of spiked samples were less than 0.59% and 2.66%, respectively. Further, the limit of detection (LOD) and LOQ were 0.02, 0.05 mg/kg, respectively, and the response was linear across the applied ranges. The crude palm oil samples analysed exhibited HMF content less than 2.27 mg/kg. Elsevier 2014-07-01 Article PeerReviewed Ariffin, Abdul Azis and Mohd Ghazali, Hasanah and Kavousi, Parviz (2014) Validation of a HPLC method for determination of hydroxymethylfurfural in crude palm oil. Food Chemistry, 154. pp. 102-107. ISSN 0308-8146; ESSN:1873-7072 http://www.sciencedirect.com/science/article/pii/S0308814613019626 10.1016/j.foodchem.2013.12.082
spellingShingle Ariffin, Abdul Azis
Mohd Ghazali, Hasanah
Kavousi, Parviz
Validation of a HPLC method for determination of hydroxymethylfurfural in crude palm oil
title Validation of a HPLC method for determination of hydroxymethylfurfural in crude palm oil
title_full Validation of a HPLC method for determination of hydroxymethylfurfural in crude palm oil
title_fullStr Validation of a HPLC method for determination of hydroxymethylfurfural in crude palm oil
title_full_unstemmed Validation of a HPLC method for determination of hydroxymethylfurfural in crude palm oil
title_short Validation of a HPLC method for determination of hydroxymethylfurfural in crude palm oil
title_sort validation of a hplc method for determination of hydroxymethylfurfural in crude palm oil
url http://psasir.upm.edu.my/id/eprint/35957/
http://psasir.upm.edu.my/id/eprint/35957/
http://psasir.upm.edu.my/id/eprint/35957/