The influence of fasting insulin level in post-gestational diabetes mellitus women receiving low-glycaemic-index diets
Post-gestational diabetes mellitus (GDM) women are recommended weight loss to manage increased cardio-metabolic risks. We investigated the effects of lowering diet glycaemic index (GI) on fasting blood glucose (FBG), serum lipids, body weight and composition of post-GDM women with varying fasting in...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/35733/ http://psasir.upm.edu.my/id/eprint/35733/1/The%20influence%20of%20fasting%20insulin%20level%20in%20post-gestational%20diabetes.pdf |
| _version_ | 1848848137093906432 |
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| author | Abdul Ghani, Rohana Shyam, Sangeetha Arshad, Fatimah Abdul Wahab, Norasyikin Chinna, Karuthan Safii, Nik Shanita Mohd Yusof, Barakatun Nisak Kamaruddin, Nor Azmi |
| author_facet | Abdul Ghani, Rohana Shyam, Sangeetha Arshad, Fatimah Abdul Wahab, Norasyikin Chinna, Karuthan Safii, Nik Shanita Mohd Yusof, Barakatun Nisak Kamaruddin, Nor Azmi |
| author_sort | Abdul Ghani, Rohana |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Post-gestational diabetes mellitus (GDM) women are recommended weight loss to manage increased cardio-metabolic risks. We investigated the effects of lowering diet glycaemic index (GI) on fasting blood glucose (FBG), serum lipids, body weight and composition of post-GDM women with varying fasting insulin levels (INS). Seventy-seven Asian, non-diabetic women with previous GDM (aged 20-40 years, mean BMI: 26.4±4.6 kgm-2) were recruited. At baseline, 20 subjects with INS <2 μIU ml-1 and 18 with INS ≥2 μIU ml-1 received conventional dietary recommendations (CHDR) only. CHDR emphasised energy and fat intake restriction and encouraged increase in dietary fibre intakes. Twenty-four subjects with INS <2 μIU ml-1 and 15 with INS ≥2 μIU ml-1, in addition to CHDR, received low-GI education (LGI). Changes in FBG, serum lipids, body weight and body composition were evaluated. Subjects with INS <2 μIU ml-1 had similar outcomes with both diets. After 1 year, subjects with INS ≥2 μIU ml-1 who received LGI education had reductions in FBG and triglycerides. Subjects who received CHDR observed increase in both FBG and triglycerides (P<0.05). Among all subjects, diet GI was lower and dietary fibre intakes were higher in LGI compared with CHDR subjects (all P<0.05). Thus, in Asian post-GDM women with normal/higher INS, adding low-GI education to CHDR improved management of FBG and triglycerides. © 2014 Macmillan Publishers Limited All rights reserved. |
| first_indexed | 2025-11-15T09:29:43Z |
| format | Article |
| id | upm-35733 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:29:43Z |
| publishDate | 2014 |
| publisher | Nature Publishing Group |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-357332016-02-04T02:36:59Z http://psasir.upm.edu.my/id/eprint/35733/ The influence of fasting insulin level in post-gestational diabetes mellitus women receiving low-glycaemic-index diets Abdul Ghani, Rohana Shyam, Sangeetha Arshad, Fatimah Abdul Wahab, Norasyikin Chinna, Karuthan Safii, Nik Shanita Mohd Yusof, Barakatun Nisak Kamaruddin, Nor Azmi Post-gestational diabetes mellitus (GDM) women are recommended weight loss to manage increased cardio-metabolic risks. We investigated the effects of lowering diet glycaemic index (GI) on fasting blood glucose (FBG), serum lipids, body weight and composition of post-GDM women with varying fasting insulin levels (INS). Seventy-seven Asian, non-diabetic women with previous GDM (aged 20-40 years, mean BMI: 26.4±4.6 kgm-2) were recruited. At baseline, 20 subjects with INS <2 μIU ml-1 and 18 with INS ≥2 μIU ml-1 received conventional dietary recommendations (CHDR) only. CHDR emphasised energy and fat intake restriction and encouraged increase in dietary fibre intakes. Twenty-four subjects with INS <2 μIU ml-1 and 15 with INS ≥2 μIU ml-1, in addition to CHDR, received low-GI education (LGI). Changes in FBG, serum lipids, body weight and body composition were evaluated. Subjects with INS <2 μIU ml-1 had similar outcomes with both diets. After 1 year, subjects with INS ≥2 μIU ml-1 who received LGI education had reductions in FBG and triglycerides. Subjects who received CHDR observed increase in both FBG and triglycerides (P<0.05). Among all subjects, diet GI was lower and dietary fibre intakes were higher in LGI compared with CHDR subjects (all P<0.05). Thus, in Asian post-GDM women with normal/higher INS, adding low-GI education to CHDR improved management of FBG and triglycerides. © 2014 Macmillan Publishers Limited All rights reserved. Nature Publishing Group 2014-02 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/35733/1/The%20influence%20of%20fasting%20insulin%20level%20in%20post-gestational%20diabetes.pdf Abdul Ghani, Rohana and Shyam, Sangeetha and Arshad, Fatimah and Abdul Wahab, Norasyikin and Chinna, Karuthan and Safii, Nik Shanita and Mohd Yusof, Barakatun Nisak and Kamaruddin, Nor Azmi (2014) The influence of fasting insulin level in post-gestational diabetes mellitus women receiving low-glycaemic-index diets. Nutrition & Diabetes, 4. art. no. e107. pp. 1-5. ISSN 2044-4052 http://www.nature.com/nutd/journal/v4/n2/abs/nutd20145a.html 10.1038/nutd.2014.5 |
| spellingShingle | Abdul Ghani, Rohana Shyam, Sangeetha Arshad, Fatimah Abdul Wahab, Norasyikin Chinna, Karuthan Safii, Nik Shanita Mohd Yusof, Barakatun Nisak Kamaruddin, Nor Azmi The influence of fasting insulin level in post-gestational diabetes mellitus women receiving low-glycaemic-index diets |
| title | The influence of fasting insulin level in post-gestational diabetes mellitus women receiving low-glycaemic-index diets |
| title_full | The influence of fasting insulin level in post-gestational diabetes mellitus women receiving low-glycaemic-index diets |
| title_fullStr | The influence of fasting insulin level in post-gestational diabetes mellitus women receiving low-glycaemic-index diets |
| title_full_unstemmed | The influence of fasting insulin level in post-gestational diabetes mellitus women receiving low-glycaemic-index diets |
| title_short | The influence of fasting insulin level in post-gestational diabetes mellitus women receiving low-glycaemic-index diets |
| title_sort | influence of fasting insulin level in post-gestational diabetes mellitus women receiving low-glycaemic-index diets |
| url | http://psasir.upm.edu.my/id/eprint/35733/ http://psasir.upm.edu.my/id/eprint/35733/ http://psasir.upm.edu.my/id/eprint/35733/ http://psasir.upm.edu.my/id/eprint/35733/1/The%20influence%20of%20fasting%20insulin%20level%20in%20post-gestational%20diabetes.pdf |