Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells
Newcastle disease virus (NDV) is an enveloped single stranded RNA virus that causes deadly infection to over 250 species of birds, comprising domestic and wild-type, thus resulting in substantial economic loss to poultry industry across the globe. NDV possesses several distinctive properties that ma...
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| Format: | Article |
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International Journal of Pharmaceutical and Clinical Research
2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/34667/ |
| _version_ | 1848847837660446720 |
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| author | Ahmed, Ismaila Ahmad, Umar Othman, Fauziah Yong, Yoke Keong |
| author_facet | Ahmed, Ismaila Ahmad, Umar Othman, Fauziah Yong, Yoke Keong |
| author_sort | Ahmed, Ismaila |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Newcastle disease virus (NDV) is an enveloped single stranded RNA virus that causes deadly infection to over 250 species of birds, comprising domestic and wild-type, thus resulting in substantial economic loss to poultry industry across the globe. NDV possesses several distinctive properties that make it an outstanding anti-cancer agent. In humans it is reported to have oncolytic and immune-stimulatory effects, precisely replicates in tumour cells while sparing normal cells and causes oncolysis. Although NDV has been extensively studied by researchers there is still need for a vigorous research on its potential use as a new treatment modality to cancer patients through a known process termed viroimmunotherapy. This paper deals with an overview of the research which has been carried out worldwide in the use of immune-stimulatory properties of NDV as an anti-cancer agent. |
| first_indexed | 2025-11-15T09:24:57Z |
| format | Article |
| id | upm-34667 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T09:24:57Z |
| publishDate | 2014 |
| publisher | International Journal of Pharmaceutical and Clinical Research |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-346672015-12-18T00:17:33Z http://psasir.upm.edu.my/id/eprint/34667/ Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells Ahmed, Ismaila Ahmad, Umar Othman, Fauziah Yong, Yoke Keong Newcastle disease virus (NDV) is an enveloped single stranded RNA virus that causes deadly infection to over 250 species of birds, comprising domestic and wild-type, thus resulting in substantial economic loss to poultry industry across the globe. NDV possesses several distinctive properties that make it an outstanding anti-cancer agent. In humans it is reported to have oncolytic and immune-stimulatory effects, precisely replicates in tumour cells while sparing normal cells and causes oncolysis. Although NDV has been extensively studied by researchers there is still need for a vigorous research on its potential use as a new treatment modality to cancer patients through a known process termed viroimmunotherapy. This paper deals with an overview of the research which has been carried out worldwide in the use of immune-stimulatory properties of NDV as an anti-cancer agent. International Journal of Pharmaceutical and Clinical Research 2014 Article PeerReviewed Ahmed, Ismaila and Ahmad, Umar and Othman, Fauziah and Yong, Yoke Keong (2014) Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells. International Journal of Pharmaceutical an d Clinical Research, 6 (3). pp. 196-200. ISSN 0975-1556 http://ijpcr.com/volume6issue3/ |
| spellingShingle | Ahmed, Ismaila Ahmad, Umar Othman, Fauziah Yong, Yoke Keong Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells |
| title | Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells |
| title_full | Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells |
| title_fullStr | Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells |
| title_full_unstemmed | Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells |
| title_short | Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells |
| title_sort | non-specific immunostimulatory capacity of newcastle disease virus (ndv) and suppression of breast cancer cells |
| url | http://psasir.upm.edu.my/id/eprint/34667/ http://psasir.upm.edu.my/id/eprint/34667/ |