Mandarin version of the Leeds Dyspepsia Questionnaire: a valid instrument for assessing symptoms in Asians

Objective To develop and validate a Mandarin version of the Leeds Dyspepsia Questionnaire (M-LDQ) in Asian patients with dyspepsia. Methods The M-LDQ was developed according to standardized methods. The validity, internal consistency, test–retest reliability and responsiveness of the instrument w...

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Main Authors: Leow, Hwong Ruey, Ching, Siew Mooi, Ramanujam, Sujarita, Yap, Choong Foong, Chia, Yook Chin, Ho, Shiaw-Hooi, Sithambaram, Suresh, Tan, Huck Joo, Goh, Khean Lee, Mahadeva, Sanjiv
Format: Article
Published: Wiley-Blackwell Publishing 2014
Online Access:http://psasir.upm.edu.my/id/eprint/34439/
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author Leow, Hwong Ruey
Ching, Siew Mooi
Ramanujam, Sujarita
Yap, Choong Foong
Chia, Yook Chin
Ho, Shiaw-Hooi
Sithambaram, Suresh
Tan, Huck Joo
Goh, Khean Lee
Mahadeva, Sanjiv
author_facet Leow, Hwong Ruey
Ching, Siew Mooi
Ramanujam, Sujarita
Yap, Choong Foong
Chia, Yook Chin
Ho, Shiaw-Hooi
Sithambaram, Suresh
Tan, Huck Joo
Goh, Khean Lee
Mahadeva, Sanjiv
author_sort Leow, Hwong Ruey
building UPM Institutional Repository
collection Online Access
description Objective To develop and validate a Mandarin version of the Leeds Dyspepsia Questionnaire (M-LDQ) in Asian patients with dyspepsia. Methods The M-LDQ was developed according to standardized methods. The validity, internal consistency, test–retest reliability and responsiveness of the instrument were evaluated in both primary and secondary care patients. Results A total of 184 patients (mean age 54.0 ± 15.8 years, of whom 59% were women and 72.3% of whom had at least secondary level education) were recruited between August 2012 and March 2013, from both primary (n = 100) and secondary care clinics (n = 84). Both the internal consistency of all components of the M-LDQ (Cronbach's α 0.79) and test–retest reliability (Spearman's correlation coefficient 0.78) were good. The M-LDQ was valid in diagnosing dyspepsia in primary care (area under the receiver operating characteristics curve 0.84) and was able to discriminate between secondary and primary care patients (median cumulative LDQ score 13.0 vs 3.0, P < 0.0001). Among eight patients with organic dyspepsia, the median M-LDQ score reduced significantly from 21.0 (pretreatment) to 9.5 (4 weeks post-treatment) (P < 0.0001). Conclusion The M-LDQ is a valid and responsive instrument for assessing ethnic Chinese adults with dyspepsia.
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spelling upm-344392015-12-15T03:05:19Z http://psasir.upm.edu.my/id/eprint/34439/ Mandarin version of the Leeds Dyspepsia Questionnaire: a valid instrument for assessing symptoms in Asians Leow, Hwong Ruey Ching, Siew Mooi Ramanujam, Sujarita Yap, Choong Foong Chia, Yook Chin Ho, Shiaw-Hooi Sithambaram, Suresh Tan, Huck Joo Goh, Khean Lee Mahadeva, Sanjiv Objective To develop and validate a Mandarin version of the Leeds Dyspepsia Questionnaire (M-LDQ) in Asian patients with dyspepsia. Methods The M-LDQ was developed according to standardized methods. The validity, internal consistency, test–retest reliability and responsiveness of the instrument were evaluated in both primary and secondary care patients. Results A total of 184 patients (mean age 54.0 ± 15.8 years, of whom 59% were women and 72.3% of whom had at least secondary level education) were recruited between August 2012 and March 2013, from both primary (n = 100) and secondary care clinics (n = 84). Both the internal consistency of all components of the M-LDQ (Cronbach's α 0.79) and test–retest reliability (Spearman's correlation coefficient 0.78) were good. The M-LDQ was valid in diagnosing dyspepsia in primary care (area under the receiver operating characteristics curve 0.84) and was able to discriminate between secondary and primary care patients (median cumulative LDQ score 13.0 vs 3.0, P < 0.0001). Among eight patients with organic dyspepsia, the median M-LDQ score reduced significantly from 21.0 (pretreatment) to 9.5 (4 weeks post-treatment) (P < 0.0001). Conclusion The M-LDQ is a valid and responsive instrument for assessing ethnic Chinese adults with dyspepsia. Wiley-Blackwell Publishing 2014-11 Article PeerReviewed Leow, Hwong Ruey and Ching, Siew Mooi and Ramanujam, Sujarita and Yap, Choong Foong and Chia, Yook Chin and Ho, Shiaw-Hooi and Sithambaram, Suresh and Tan, Huck Joo and Goh, Khean Lee and Mahadeva, Sanjiv (2014) Mandarin version of the Leeds Dyspepsia Questionnaire: a valid instrument for assessing symptoms in Asians. Journal of Digestive Diseases, 15 (11). pp. 591-596. ISSN 1751-2972; ESSN: 1751-2980 http://onlinelibrary.wiley.com/doi/10.1111/1751-2980.12183/abstract 10.1111/1751-2980.12183
spellingShingle Leow, Hwong Ruey
Ching, Siew Mooi
Ramanujam, Sujarita
Yap, Choong Foong
Chia, Yook Chin
Ho, Shiaw-Hooi
Sithambaram, Suresh
Tan, Huck Joo
Goh, Khean Lee
Mahadeva, Sanjiv
Mandarin version of the Leeds Dyspepsia Questionnaire: a valid instrument for assessing symptoms in Asians
title Mandarin version of the Leeds Dyspepsia Questionnaire: a valid instrument for assessing symptoms in Asians
title_full Mandarin version of the Leeds Dyspepsia Questionnaire: a valid instrument for assessing symptoms in Asians
title_fullStr Mandarin version of the Leeds Dyspepsia Questionnaire: a valid instrument for assessing symptoms in Asians
title_full_unstemmed Mandarin version of the Leeds Dyspepsia Questionnaire: a valid instrument for assessing symptoms in Asians
title_short Mandarin version of the Leeds Dyspepsia Questionnaire: a valid instrument for assessing symptoms in Asians
title_sort mandarin version of the leeds dyspepsia questionnaire: a valid instrument for assessing symptoms in asians
url http://psasir.upm.edu.my/id/eprint/34439/
http://psasir.upm.edu.my/id/eprint/34439/
http://psasir.upm.edu.my/id/eprint/34439/