Inhibition of epithelial CC-family chemokine synthesis by the synthetic chalcone DMPF-1 via disruption of NF-κB nuclear translocation and suppression of experimental asthma in mice
Asthma is associated with increased pulmonary inflammation and airway hyperresponsiveness. The interaction between airway epithelium and inflammatory mediators plays a key role in the pathogenesis of asthma. In vitro studies evaluated the inhibitory effects of 3-(2,5-dimethoxyphenyl)-1-(5-methylfura...
| Main Authors: | Rajajendram, Revathee, Tham, Chau Ling, Akhtar, Mohamad Nadeem, Sulaiman, Mohd Roslan, Israf Ali, Daud Ahmad |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hindawi Publishing Corporation
2015
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/34211/ http://psasir.upm.edu.my/id/eprint/34211/1/Inhibition%20of%20Epithelial%20CC-Family%20Chemokine.pdf |
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