Induction of apoptosis in MCF-7 cells via oxidative stress generation, mitochondria-dependent and caspase-independent pathway by ethyl acetate extract of Dillenia suffruticosa and its chemical profile
Dillenia suffruticosa, which is locally known as Simpoh air, has been traditionally used to treat cancerous growth. The ethyl acetate extract of D. suffruticosa (EADs) has been shown to induce apoptosis in MCF-7 breast cancer cells in our previous study. The present study aimed to elucidate the mole...
| Main Authors: | Tor, Yin Sim, Saiful Yazan, Latifah, Foo, Jhi Biau, Wibowo, Agustono, Ismail, Norsharina, Cheah, Yoke Kqueen, Abdullah, Rasedee, Ismail, Maznah, Ismail, Intan Safinar, Yeap, Swee Keong |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science
2015
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/34169/ http://psasir.upm.edu.my/id/eprint/34169/1/journal.pone.0127441.PDF |
Similar Items
Induction of apoptosis through oxidative stress-related pathways in MCF-7, human breast cancer cells, by ethyl acetate extract of Dillenia suffruticosa
by: Tor, Yin Sim, et al.
Published: (2014)
by: Tor, Yin Sim, et al.
Published: (2014)
Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signalling pathways
by: Foo, Jhi Biau, et al.
Published: (2014)
by: Foo, Jhi Biau, et al.
Published: (2014)
Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signaling pathways
by: Foo, Jhi Biau, et al.
Published: (2014)
by: Foo, Jhi Biau, et al.
Published: (2014)
Dillenia suffruticosa extract inhibits proliferation of human breast cancer cell lines (MCF-7 and MDA-MB-231) via induction of G2/M arrest and apoptosis
by: Armania, Nurdin, et al.
Published: (2013)
by: Armania, Nurdin, et al.
Published: (2013)
Induction of apoptosis and the signalling pathways involved by dillenia suffruticosa dichloromethane root extract in mcf-7 and mda-mb-231 breast cancer cells
by: Foo, Jhi Biau
Published: (2015)
by: Foo, Jhi Biau
Published: (2015)
Dillenia suffruticosa dichloromethane root extract induced apoptosis towards MDA-MB-231 triple negative breast cancer cells
by: Foo, J. B., et al.
Published: (2016)
by: Foo, J. B., et al.
Published: (2016)
Apoptotic-related signalling pathways in mcf-7 cells treated with ethyl acetate extract of dillenia suffruticosa, and isolation of its major compounds
by: Yin, Sim Tor
Published: (2015)
by: Yin, Sim Tor
Published: (2015)
Dillenia suffruticosa exhibited antioxidant and cytotoxic activity through induction of apoptosis and G2/M cell cycle arrest
by: Armania, Nurdin, et al.
Published: (2013)
by: Armania, Nurdin, et al.
Published: (2013)
Extracts of Dillenia suffruticosa for medical treatments
by: Saiful Yazan, Latifah, et al.
Published: (2012)
by: Saiful Yazan, Latifah, et al.
Published: (2012)
Anti breast cancer properties and toxicity of Dillenia suffruticosa root aqueous extract in BALB/c mice
by: Saiful Yazan, Latifah, et al.
Published: (2015)
by: Saiful Yazan, Latifah, et al.
Published: (2015)
Bioassay-guided isolation of Triterpene compounds from Dillenia suffruticosa and their cytotoxic activities against cancer cells
by: Nurdin, Armania, et al.
Published: (2021)
by: Nurdin, Armania, et al.
Published: (2021)
Bioassay-guided isolation of triterpene compounds from Dillenia suffruticosa and their cytotoxic activities against cancer cells
by: Armania Nurdin,, et al.
Published: (2022)
by: Armania Nurdin,, et al.
Published: (2022)
Estimation of the aboveground biomass in a Dillenia suffruticosa stand, Malaysia
by: Kueh, Roland Jui Heng, et al.
Published: (2014)
by: Kueh, Roland Jui Heng, et al.
Published: (2014)
Phytochemical screening, antioxidant and antibacterial activities of extracts and fractions of Dillenia suffruticosa leaves
by: Farazimah Yakop,, et al.
Published: (2020)
by: Farazimah Yakop,, et al.
Published: (2020)
Antibacterial activity of Dillenia suffruticosa leaf extract against Xanthomonas oryzae pv. oryzae
by: Sani, Mohd Fardzryn
Published: (2016)
by: Sani, Mohd Fardzryn
Published: (2016)
Antiproliferation and induction of caspase-8-dependent mitochondria-mediated apoptosis by β-tocotrienol in human lung and brain cancer cell lines
by: Lim, Su Wen, et al.
Published: (2014)
by: Lim, Su Wen, et al.
Published: (2014)
Zerumbone induces apoptosis in Jurkat T-cell line via activation of caspase 3 and caspase 9
by: Rahman, Heshu Sulaiman, et al.
Published: (2012)
by: Rahman, Heshu Sulaiman, et al.
Published: (2012)
Clausenidin induces caspase-dependent apoptosis in colon cancer
by: Waziri, Peter M., et al.
Published: (2016)
by: Waziri, Peter M., et al.
Published: (2016)
Dillenia suffruticosa dichloromethane root extract reduced metastasis of 4T1 cells to the liver and heart without causing toxicity in female BALB/c mice
by: Saiful Yazan, Latifah, et al.
Published: (2019)
by: Saiful Yazan, Latifah, et al.
Published: (2019)
Kandungan logam berat dalam persekitaran tanih dan dillenia suffruticosa di Kawasan Lombong Pelepah Kanan, Kota Tinggi Johor
by: Sahibin Abd. Rahim,, et al.
Published: (2011)
by: Sahibin Abd. Rahim,, et al.
Published: (2011)
Induction of apoptosis and G2/M arrest by ampelopsin E from Dryobalanops towards triple negative breast cancer cells, MDA-MB-231
by: Abd Rahman, Napsiah, et al.
Published: (2016)
by: Abd Rahman, Napsiah, et al.
Published: (2016)
Recent advances in apoptosis, mitochondria and drug resistance in cancer cells
by: Indran, I., et al.
Published: (2011)
by: Indran, I., et al.
Published: (2011)
Cardamonin induces apoptosis in human nasopharyngeal carcinoma cells via mitochondrial death pathway mediated by caspase-3 and caspase-8 activation, independent of caspase-9 signalling responses
by: Chiang, Michelle
Published: (2016)
by: Chiang, Michelle
Published: (2016)
Induction of cell cycle arrest and apoptosis by copper complex Cu(SBCM)₂ towards oestrogen-receptor positive MCF-7 breast cancer cells
by: Jhi, Biau Foo, et al.
Published: (2019)
by: Jhi, Biau Foo, et al.
Published: (2019)
Caspases-3 and -7 are activated in goniothalamin-induced apoptosis in human Jurkat T-cells
by: Inayat-Hussain, Salmaan H., et al.
Published: (1999)
by: Inayat-Hussain, Salmaan H., et al.
Published: (1999)
Arborinine from Glycosmis Pentaphylla (retz.) DC induces apoptosis through activation of Caspase-3/7 in human mammary gland Adenocarcinoma (MCF-7) cell line
by: Mohd Hussain, Nurlaili Najmie, et al.
Published: (2016)
by: Mohd Hussain, Nurlaili Najmie, et al.
Published: (2016)
Kenaf seed oil from supercritical carbon dioxide fluid extraction induced G1 phase cell cycle arrest and apoptosis in leukemia cells
by: Foo, Jhi Biau, et al.
Published: (2011)
by: Foo, Jhi Biau, et al.
Published: (2011)
Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis
by: Treude, Fabian, et al.
Published: (2014)
by: Treude, Fabian, et al.
Published: (2014)
Induction of Caspase-2 Activation by a DNA Enzyme Evokes Tumor Cell Apoptosis
by: Kim, Soo-Hyun, et al.
Published: (2012)
by: Kim, Soo-Hyun, et al.
Published: (2012)
The Role Of Caspase-Activated Dnase (Cad) In Chromosome Breaks During Oxidative Stressinduced Apoptosis
by: Boon, Siaw Shi
Published: (2009)
by: Boon, Siaw Shi
Published: (2009)
Goniothalamin selectively induces apoptosis on human hepatoblastoma cells through caspase-3 activation.
by: Al-Qubaisi, Mothanna, et al.
Published: (2013)
by: Al-Qubaisi, Mothanna, et al.
Published: (2013)
Caspase-3 and caspase-8 expression in breast cancer: caspase-3 is associated with survival
by: Xuan, Pu, et al.
Published: (2016)
by: Xuan, Pu, et al.
Published: (2016)
Caspase-dependent apoptotic mechanism of gallic acid and its
derivatives isolated from quercus infectoria ethyl acetate extract against cervical cancer cells lines (hela)
by: Ismail, Illyana
Published: (2023)
by: Ismail, Illyana
Published: (2023)
Antiproliferative And Apoptosis Effects Of Clinacanthus Nutans Leaf Extract On Breast Cancer Cell (Mcf7)
by: Ismail, Noor Zafirah
Published: (2023)
by: Ismail, Noor Zafirah
Published: (2023)
Phorbol esters from Jatropha meal triggered apoptosis, activated PKC-δ, Caspase-3 proteins and down-regulated the proto-oncogenes in MCF-7 and HeLa cancer cell lines
by: Oskoueian, Ehsan, et al.
Published: (2012)
by: Oskoueian, Ehsan, et al.
Published: (2012)
Curcumin Analog DK1 Induces Apoptosis in Human Osteosarcoma Cells In Vitro through Mitochondria-Dependent Signaling Pathway
by: Muhammad Nazirul Mubin, Aziz, et al.
Published: (2018)
by: Muhammad Nazirul Mubin, Aziz, et al.
Published: (2018)
Curcumin analog DK1 induces apoptosis in human osteosarcoma cells in vitro through mitochondria-dependent signaling pathway
by: Aziz, Muhammad Nazirul Mubin, et al.
Published: (2018)
by: Aziz, Muhammad Nazirul Mubin, et al.
Published: (2018)
Apoptosis and cell cycle arrest of human colorectal cancer cell line HT-29 induced by vanillin.
by: Ho, Ket Li, et al.
Published: (2009)
by: Ho, Ket Li, et al.
Published: (2009)
A novel Osmium-based compound targets the mitochondria and triggers ROS-dependent apoptosis in colon carcinoma
by: Maillet, A., et al.
Published: (2013)
by: Maillet, A., et al.
Published: (2013)
Repressing the activity of protein kinase CK2 releases the brakes on mitochondria-mediated apoptosis in cancer cells
by: Hanif, I., et al.
Published: (2011)
by: Hanif, I., et al.
Published: (2011)
Similar Items
-
Induction of apoptosis through oxidative stress-related pathways in MCF-7, human breast cancer cells, by ethyl acetate extract of Dillenia suffruticosa
by: Tor, Yin Sim, et al.
Published: (2014) -
Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signalling pathways
by: Foo, Jhi Biau, et al.
Published: (2014) -
Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signaling pathways
by: Foo, Jhi Biau, et al.
Published: (2014) -
Dillenia suffruticosa extract inhibits proliferation of human breast cancer cell lines (MCF-7 and MDA-MB-231) via induction of G2/M arrest and apoptosis
by: Armania, Nurdin, et al.
Published: (2013) -
Induction of apoptosis and the signalling pathways involved by dillenia suffruticosa dichloromethane root extract in mcf-7 and mda-mb-231 breast cancer cells
by: Foo, Jhi Biau
Published: (2015)