Extracts of Dillenia suffruticosa for medical treatments

QR Code

Extracts of Dillenia suffruticosa for medical treatments

The present invention relates to methanolic and/or aqueous and/or ethyl acetate and/or dichloromethane extract of Dillenia suffruticosa for use in the treatment of solid cancer tumours, and as antimicrobial and antioxidant agents. It also relates to their preparation and dosage.

Bibliographic Details
Main Authors:	Saiful Yazan, Latifah, Ithnin @ Mokngin, Hairuszah, Nurdin, Armania, Ismail, Maznah, Husain, Noreen, Said, Zulfahmi, Ismail, Intan Safinar, Abdul Rahman, Mohd Shukri, Harun, Mohd. Nawi
Format:	Patent
Published:	2012
Online Access:	http://psasir.upm.edu.my/id/eprint/33523/

Similar Items

Bioassay-guided isolation of Triterpene compounds from Dillenia suffruticosa and their cytotoxic activities against cancer cells
by: Nurdin, Armania, et al.
Published: (2021)

Bioassay-guided isolation of triterpene compounds from Dillenia suffruticosa and their cytotoxic activities against cancer cells
by: Armania Nurdin,, et al.
Published: (2022)

Dillenia suffruticosa exhibited antioxidant and cytotoxic activity through induction of apoptosis and G2/M cell cycle arrest
by: Armania, Nurdin, et al.
Published: (2013)

Dillenia suffruticosa extract inhibits proliferation of human breast cancer cell lines (MCF-7 and MDA-MB-231) via induction of G2/M arrest and apoptosis
by: Armania, Nurdin, et al.
Published: (2013)

Dillenia suffruticosa dichloromethane root extract induced apoptosis towards MDA-MB-231 triple negative breast cancer cells
by: Foo, J. B., et al.
Published: (2016)

Induction of apoptosis through oxidative stress-related pathways in MCF-7, human breast cancer cells, by ethyl acetate extract of Dillenia suffruticosa
by: Tor, Yin Sim, et al.
Published: (2014)

Dillenia species: a review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies
by: Saiful Yazan, Latifah, et al.
Published: (2014)

Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signalling pathways
by: Foo, Jhi Biau, et al.
Published: (2014)

Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signaling pathways
by: Foo, Jhi Biau, et al.
Published: (2014)

The improvement of in vivo model (Balb/c mice) for cervical carcinogenesis using diethylstilbestrol (DES)
by: Zulfahmi, Said, et al.
Published: (2013)

Anti breast cancer properties and toxicity of Dillenia suffruticosa root aqueous extract in BALB/c mice
by: Saiful Yazan, Latifah, et al.
Published: (2015)

Estimation of the aboveground biomass in a Dillenia suffruticosa stand, Malaysia
by: Kueh, Roland Jui Heng, et al.
Published: (2014)

Induction of apoptosis in MCF-7 cells via oxidative stress generation, mitochondria-dependent and caspase-independent pathway by ethyl acetate extract of Dillenia suffruticosa and its chemical profile
by: Tor, Yin Sim, et al.
Published: (2015)

Phytochemical screening, antioxidant and antibacterial activities of extracts and fractions of Dillenia suffruticosa leaves
by: Farazimah Yakop,, et al.
Published: (2020)

Antibacterial activity of Dillenia suffruticosa leaf extract against Xanthomonas oryzae pv. oryzae
by: Sani, Mohd Fardzryn
Published: (2016)

Dillenia suffruticosa dichloromethane root extract reduced metastasis of 4T1 cells to the liver and heart without causing toxicity in female BALB/c mice
by: Saiful Yazan, Latifah, et al.
Published: (2019)

Kandungan logam berat dalam persekitaran tanih dan dillenia suffruticosa di Kawasan Lombong Pelepah Kanan, Kota Tinggi Johor
by: Sahibin Abd. Rahim,, et al.
Published: (2011)

Apoptotic-related signalling pathways in mcf-7 cells treated with ethyl acetate extract of dillenia suffruticosa, and isolation of its major compounds
by: Yin, Sim Tor
Published: (2015)

Induction of apoptosis and the signalling pathways involved by dillenia suffruticosa dichloromethane root extract in mcf-7 and mda-mb-231 breast cancer cells
by: Foo, Jhi Biau
Published: (2015)

Germinated brown rice (GBR) reduces the incidence of aberrant crypt foci with the involvement of β-catenin and COX-2 in azoxymethane-induced colon cancer in rats.
by: Saiful Yazan, Latifah, et al.
Published: (2010)

Effects of storage temperature on seed maturation of dillenia suffroticosa
by: Mohamad Safri, bin Alwi Umar
Published: (2004)

Antioxidant And Antimicrobial Properties Of Tree Peony (Paeonia Suffruticosa) And Apple Flower (Malus Spp.)
by: Han, Ching Voon
Published: (2014)

Effects of thymoquinone rich fraction and thymoquinone on plasma lipoprotein levels and hepatic low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase genes expression.
by: Al-Naqeep, Ghanya, et al.
Published: (2009)

Thymoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with down-regulation of Bcl-2 protein
by: Ng, Wei Keat, et al.
Published: (2011)

Apoptosis and cell cycle arrest of human colorectal cancer cell line HT-29 induced by vanillin.
by: Ho, Ket Li, et al.
Published: (2009)

Toxicology study of vanillin on rats via oral and intra-peritoneal administration
by: Ismail, Maznah, et al.
Published: (2010)

Toxicology study of vanillin on rats via oral and intra-peritoneal administration.
by: Ho, Ket Li, et al.
Published: (2011)

The hypocholesterolemic effect of germinated brown rice involves the upregulation of the apolipoprotein A1 and low-density lipoprotein receptor genes
by: Imam, Mustapha Umar, et al.
Published: (2013)

The hypocholesterolemic effect of germinated brown rice involves the upregulation of the apolipoprotein A1 and low-density lipoprotein receptor genes
by: Imam, Mustapha Umar, et al.
Published: (2013)

Cytotoxic properties of anthraquinones (nordamnacanthal and damnacanthal) from roots of Morinda elliptica
by: Saiful Yazan, Latifah
Published: (2003)

Composition comprising phaleria leaf extract having anti-cancer activity
by: Abdullah, Luqman Chuah, et al.
Published: (2013)

Cytotoxicity of Thymoquinone (TQ) from Nigella sativa towards human cervical carcinoma cells (HeLa).
by: Saiful Yazan, Latifah, et al.
Published: (2009)

Effects of germinated brown rice and its bioactive compounds on the expression of the peroxisome proliferator-activated receptor gamma gene
by: Imam, Mustapha Umar, et al.
Published: (2013)

Removal of selected organic pollutants in landfill leachate using natural coagulant from dillenia indica seed extract / Aziz Ahmed
by: Aziz , Ahmed
Published: (2021)

Polyphenol-rich ethyl acetate fraction isolated from Molineria latifolia ameliorates insulin resistance in experimental diabetic rats via IRS1/AKT activation
by: Ooi, Der Jiun, et al.
Published: (2018)

Cytotoxicity and exposure assessment of PM2.5 in a residential home during COVID-19 lockdown
by: Mahamud, Ummi Sabariah, et al.
Published: (2024)

The histomorphological analysis of liver following administration of low doses of diclofenac and ibuprofen
by: Mohanambal, Moorthy, et al.
Published: (2009)

Moringa oleifera enhances liver antioxidant status via elevation of antioxidant enzymes activity and counteracts paracetamol-induced hepatotoxicity.
by: Nanthini, Uma, et al.
Published: (2010)

Morphological alteration in mitochondria following diclofenac and ibuprofen administration.
by: Moorthy, Mohanambal, et al.
Published: (2008)

Moringa oleifera Lam prevents acetaminophen induced liver injury through restoration of glutathione level
by: Fakurazi, Sharida, et al.
Published: (2008)