Use of the curcumin analog BHMC in the treatment of endothelial dysfunction and related disorders
The present invention relates to an analog of curcumin, 2,6-bis-(4-hydroxyl-3-methoxybenzylidine)cyclohexanone (BHMC) or a pharmaceutically acceptable salt, solvate or derivative thereof, for use in treating, preventing or managing endothelial dysfunction and/or a disorder associated with endothelia...
| Main Authors: | , , , |
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| Format: | Patent |
| Published: |
2012
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| Online Access: | http://psasir.upm.edu.my/id/eprint/33360/ |
| _version_ | 1848847474382340096 |
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| author | Israf Ali, Daud Ahmad Tham, Chau Ling Lajis, Mohd Nordin Lam, Kok Wai |
| author_facet | Israf Ali, Daud Ahmad Tham, Chau Ling Lajis, Mohd Nordin Lam, Kok Wai |
| author_sort | Israf Ali, Daud Ahmad |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The present invention relates to an analog of curcumin, 2,6-bis-(4-hydroxyl-3-methoxybenzylidine)cyclohexanone (BHMC) or a pharmaceutically acceptable salt, solvate or derivative thereof, for use in treating, preventing or managing endothelial dysfunction and/or a disorder associated with endothelial dysfunction. Furthermore provided are methods of treating, preventing or managing endothelial dysfunction and/or a disorder associated with endothelial dysfunction using BHMC or a pharmaceutically acceptable salt, solvate or derivative thereof. The invention provides also a method for attenuating endothelial dysfunction in an endothelial cell and/or attenuating the hallmarks of endothelial dysfunction in an endothelial cell. |
| first_indexed | 2025-11-15T09:19:11Z |
| format | Patent |
| id | upm-33360 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T09:19:11Z |
| publishDate | 2012 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-333602015-02-05T04:21:03Z http://psasir.upm.edu.my/id/eprint/33360/ Use of the curcumin analog BHMC in the treatment of endothelial dysfunction and related disorders Israf Ali, Daud Ahmad Tham, Chau Ling Lajis, Mohd Nordin Lam, Kok Wai The present invention relates to an analog of curcumin, 2,6-bis-(4-hydroxyl-3-methoxybenzylidine)cyclohexanone (BHMC) or a pharmaceutically acceptable salt, solvate or derivative thereof, for use in treating, preventing or managing endothelial dysfunction and/or a disorder associated with endothelial dysfunction. Furthermore provided are methods of treating, preventing or managing endothelial dysfunction and/or a disorder associated with endothelial dysfunction using BHMC or a pharmaceutically acceptable salt, solvate or derivative thereof. The invention provides also a method for attenuating endothelial dysfunction in an endothelial cell and/or attenuating the hallmarks of endothelial dysfunction in an endothelial cell. 2012-08-02 Patent NonPeerReviewed Daud Ahmad Israf Ali (2012) Use of the curcumin analog BHMC in the treatment of endothelial dysfunction and related disorders. PI2012003491. |
| spellingShingle | Israf Ali, Daud Ahmad Tham, Chau Ling Lajis, Mohd Nordin Lam, Kok Wai Use of the curcumin analog BHMC in the treatment of endothelial dysfunction and related disorders |
| title | Use of the curcumin analog BHMC in the treatment of endothelial dysfunction and related disorders |
| title_full | Use of the curcumin analog BHMC in the treatment of endothelial dysfunction and related disorders |
| title_fullStr | Use of the curcumin analog BHMC in the treatment of endothelial dysfunction and related disorders |
| title_full_unstemmed | Use of the curcumin analog BHMC in the treatment of endothelial dysfunction and related disorders |
| title_short | Use of the curcumin analog BHMC in the treatment of endothelial dysfunction and related disorders |
| title_sort | use of the curcumin analog bhmc in the treatment of endothelial dysfunction and related disorders |
| url | http://psasir.upm.edu.my/id/eprint/33360/ |