A method for producing polymer-encapsulated nanoparticles

The present invention relates to a method for producingpolymer-encapsulated nanoparticles comprising the steps of: pumping supercritical fluid into a pressurised vessel, at a predetermined pressure; spraying a solution comprising a compound to be encapsulated, a polymer and an organic solvent into t...

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Bibliographic Details
Main Authors: Yunus, Robiah, Kalani, Mahshid
Format: Patent
Published: 2011
Online Access:http://psasir.upm.edu.my/id/eprint/33157/
Description
Summary:The present invention relates to a method for producingpolymer-encapsulated nanoparticles comprising the steps of: pumping supercritical fluid into a pressurised vessel, at a predetermined pressure; spraying a solution comprising a compound to be encapsulated, a polymer and an organic solvent into the vessel; collecting precipitated particles on a filter; and washing the particles with the supercritical fluid to remove residual solvent; characterised in that: the difference between the melting point of the polymer and the melting point of the compound to be encapsulated is not more than 10C.