Dose optimisation of 18F-flurodeoxyglucose for whole body PET oncology examination in CDNI of UPM

A shift to administration of optimal dose of18F-FDG between 4 and 5 MBq/kg from the current practice of higher doses potentially yields a reasonable-to-excellent PET image. For this purpose, whole-body MIP images of 32 patients (23 men, 9 women, age 51.9 ± 13.7 years), administered with 18F-FDG (act...

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Main Authors: Hassan, Hishar, Mustafa, Salasiah, Ahmad Saad, Fathinul Fikri, Nordin, Abdul Jalil
Other Authors: Osman, Mohd Nizam
Format: Article
Language:English
Published: Universiti Putra Malaysia Press 2015
Online Access:http://psasir.upm.edu.my/id/eprint/32731/
http://psasir.upm.edu.my/id/eprint/32731/1/03%20JST-0524-2014%20Short%20Comm%20Rev.pdf
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author Hassan, Hishar
Mustafa, Salasiah
Ahmad Saad, Fathinul Fikri
Nordin, Abdul Jalil
author2 Osman, Mohd Nizam
author_facet Osman, Mohd Nizam
Hassan, Hishar
Mustafa, Salasiah
Ahmad Saad, Fathinul Fikri
Nordin, Abdul Jalil
author_sort Hassan, Hishar
building UPM Institutional Repository
collection Online Access
description A shift to administration of optimal dose of18F-FDG between 4 and 5 MBq/kg from the current practice of higher doses potentially yields a reasonable-to-excellent PET image. For this purpose, whole-body MIP images of 32 patients (23 men, 9 women, age 51.9 ± 13.7 years), administered with 18F-FDG (activity 5.3 ± 0.5 MBq/kg, 45 minutes uptake time) for whole-body PET/CT examinations, were evaluated. Image quality was assessed visually by two radiologists using a three-point scoring scale: poor, reasonable and excellent. The interobserver agreement revealed a kappa value higher than 0.7. Therefore, the utilisation of 18F-FDG dose between 4 and 5MBq/kg is considered an optimum dose for whole-body PET/CT examination.
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spelling upm-327312016-01-26T04:39:40Z http://psasir.upm.edu.my/id/eprint/32731/ Dose optimisation of 18F-flurodeoxyglucose for whole body PET oncology examination in CDNI of UPM Hassan, Hishar Mustafa, Salasiah Ahmad Saad, Fathinul Fikri Nordin, Abdul Jalil A shift to administration of optimal dose of18F-FDG between 4 and 5 MBq/kg from the current practice of higher doses potentially yields a reasonable-to-excellent PET image. For this purpose, whole-body MIP images of 32 patients (23 men, 9 women, age 51.9 ± 13.7 years), administered with 18F-FDG (activity 5.3 ± 0.5 MBq/kg, 45 minutes uptake time) for whole-body PET/CT examinations, were evaluated. Image quality was assessed visually by two radiologists using a three-point scoring scale: poor, reasonable and excellent. The interobserver agreement revealed a kappa value higher than 0.7. Therefore, the utilisation of 18F-FDG dose between 4 and 5MBq/kg is considered an optimum dose for whole-body PET/CT examination. Universiti Putra Malaysia Press Osman, Mohd Nizam 2015-07 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/32731/1/03%20JST-0524-2014%20Short%20Comm%20Rev.pdf Hassan, Hishar and Mustafa, Salasiah and Ahmad Saad, Fathinul Fikri and Nordin, Abdul Jalil (2015) Dose optimisation of 18F-flurodeoxyglucose for whole body PET oncology examination in CDNI of UPM. Pertanika Journal of Science & Technology, 23 (2). pp. 187-192. ISSN 0128-7680; ESSN: 2231-8526 http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JST%20Vol.%2023%20%282%29%20Jul.%202015/03%20JST-0524-2014%20Short%20Comm%20Rev.pdf
spellingShingle Hassan, Hishar
Mustafa, Salasiah
Ahmad Saad, Fathinul Fikri
Nordin, Abdul Jalil
Dose optimisation of 18F-flurodeoxyglucose for whole body PET oncology examination in CDNI of UPM
title Dose optimisation of 18F-flurodeoxyglucose for whole body PET oncology examination in CDNI of UPM
title_full Dose optimisation of 18F-flurodeoxyglucose for whole body PET oncology examination in CDNI of UPM
title_fullStr Dose optimisation of 18F-flurodeoxyglucose for whole body PET oncology examination in CDNI of UPM
title_full_unstemmed Dose optimisation of 18F-flurodeoxyglucose for whole body PET oncology examination in CDNI of UPM
title_short Dose optimisation of 18F-flurodeoxyglucose for whole body PET oncology examination in CDNI of UPM
title_sort dose optimisation of 18f-flurodeoxyglucose for whole body pet oncology examination in cdni of upm
url http://psasir.upm.edu.my/id/eprint/32731/
http://psasir.upm.edu.my/id/eprint/32731/
http://psasir.upm.edu.my/id/eprint/32731/1/03%20JST-0524-2014%20Short%20Comm%20Rev.pdf