Dose optimisation of 18F-flurodeoxyglucose for whole body PET oncology examination in CDNI of UPM
A shift to administration of optimal dose of18F-FDG between 4 and 5 MBq/kg from the current practice of higher doses potentially yields a reasonable-to-excellent PET image. For this purpose, whole-body MIP images of 32 patients (23 men, 9 women, age 51.9 ± 13.7 years), administered with 18F-FDG (act...
| Main Authors: | , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Universiti Putra Malaysia Press
2015
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/32731/ http://psasir.upm.edu.my/id/eprint/32731/1/03%20JST-0524-2014%20Short%20Comm%20Rev.pdf |
| Summary: | A shift to administration of optimal dose of18F-FDG between 4 and 5 MBq/kg from the current practice of higher doses potentially yields a reasonable-to-excellent PET image. For this purpose, whole-body MIP images of 32 patients (23 men, 9 women, age 51.9 ± 13.7 years), administered with 18F-FDG (activity 5.3 ± 0.5 MBq/kg, 45 minutes uptake time) for whole-body PET/CT examinations, were evaluated. Image quality was assessed visually by two radiologists using a three-point scoring scale: poor, reasonable and excellent. The interobserver agreement revealed a kappa value higher than 0.7. Therefore, the utilisation of 18F-FDG dose between 4 and 5MBq/kg is considered an optimum dose for whole-body PET/CT examination. |
|---|