Methods and compositions for the prevention of opiate tolerance using mitragynine.

QR Code

Methods and compositions for the prevention of opiate tolerance using mitragynine.

The present invention relates to methods and compositions to counter the side effects of analgesic treatments with opioids such as morphine. Provided are novel treatment regimes comprising the administration of mitragynine for the prevention, reversal and/or delay of the progression and/or developme...

Full description

Bibliographic Details
Main Authors:	Fakurazi, Sharida, Baharuldin, Mohamad Taufik Hidayat, Mohd Moklas, Mohamad Aris, Ithnin, Hairuszah, Abd Rahman, Shamima
Format:	Patent
Language:	English
Published:	2011
Online Access:	http://psasir.upm.edu.my/id/eprint/32077/

Similar Items

The combination of mitragynine and morphine prevents the development of morphine tolerance in mice
by: Fakurazi, Sharida, et al.
Published: (2013)

Antinociceptive action of isolated mitragynine from Mitragyna speciosa through activation of opioid receptor system
by: Abdul Rahman, Shamima, et al.
Published: (2012)

Determination of mitragynine bound opioid receptors
by: Baharuldin, Mohamad Taufik Hidayat, et al.
Published: (2010)

Effects of mitragynine from Mitragyna speciosa Korth leaves on working memory
by: Apryani, Evhy, et al.
Published: (2010)

Antidepressant-like effect of mitragynine isolated from Mitragyna speciosa Korth in mice model of depression.
by: Nasir, Farah Idayu, et al.
Published: (2011)

Moringa oleifera Lam prevents acetaminophen induced liver injury through restoration of glutathione level
by: Fakurazi, Sharida, et al.
Published: (2008)

Pharmacokinetic And Pharmacodynamic Modeling Of Mitragynine In PainTolerance
by: Ramachandram, Dinesh Sangarran
Published: (2020)

Antidepressant-like effects of omega-3 fatty acids in postpartum model of depression in rats
by: Arbabi, Leila, et al.
Published: (2014)

Enhanced antinociceptive effects of mitragynine in combination with morphine via opioid receptors activation
by: Abdul Rahman, Shamima
Published: (2014)

Antidepressant-like effect of methanolic extract of Punica granatum (pomegranate) in mice model of depression
by: Abdul Rahman, Shamima, et al.
Published: (2015)

Development of PCR Method for the Detection of mu Opiate Receptor Polymorphism
by: Talib, Nazila
Published: (2009)

The histomorphological analysis of liver following administration of low doses of diclofenac and ibuprofen
by: Mohanambal, Moorthy, et al.
Published: (2009)

Moringa oleifera enhances liver antioxidant status via elevation of antioxidant enzymes activity and counteracts paracetamol-induced hepatotoxicity.
by: Nanthini, Uma, et al.
Published: (2010)

Morphological alteration in mitochondria following diclofenac and ibuprofen administration.
by: Moorthy, Mohanambal, et al.
Published: (2008)

Hepatoprotective and antioxidant action of Moringa oleifera lam. againsts acetaminophen induced hepatoxicity in rats.
by: Fakurazi, Sharida, et al.
Published: (2008)

Antidepressant-like effect of lipid extract of Channa striatus in chronic unpredictable mild stress model of depression in rats
by: Abdul Shukkoor, Mohamed Saleem, et al.
Published: (2016)

A Clinical And Pharmacogenetic Investigation Of Methadone Maintenance Therapy (MMT) In Opiate Dependent Individuals
by: Mohamad, Nasir
Published: (2011)

Opiate Drug Consumption Patterns In Asia- Report Of A Regional Workshop.
Published: (1981)

Inhibitory activity of Ficus deltoidea var. trengganuensis Aqueous extract on lipopolysaccharide-induced TNF-α production from microglia
by: Wang, Huiling, et al.
Published: (2017)

Development Of An Immunoassay For Mitragynine
by: Lee , Mei Jin
Published: (2016)

Centella asiatica prevents chronic unpredictable mild stress-induced behavioral changes in rats
by: Jagadeesan, Saravanan, et al.
Published: (2019)

Antidepressant-like effect of aqueous extract of Channa striatus fillet in mice models of depression.
by: Saleem, A. M., et al.
Published: (2011)

The effect of pretreatment of zerumbone on fatty liver following ethanol induced Hepatotoxicity
by: Fakurazi, Sharida, et al.
Published: (2008)

Methyl ester and aromatic ether modification of mitragynine for generation of mitragynine-specific polyclonal antibodies
by: Mustafa, Radhiahtul Raehan, et al.
Published: (2022)

Mitragynine as an anthelmintic for caprine strongyles
by: Abdul Aziz, Farah Hida, et al.
Published: (2012)

Involvement of monoaminergic system in the antidepressant-like effect of aqueous extract of Channa striatus in mice
by: Saleem, A. M., et al.
Published: (2013)

The evolutionary development in drug discovery and delivery
by: Ithnin, Hairuszah, et al.
Published: (2013)

Alpha lipoic acid posses dual antioxidant and lipid lowering properties in athersclerotic-induced New Zealand white rabbit
by: Amom, Zulkhairi, et al.
Published: (2008)

Variability of plasma methadone concentration in opiate dependents receiving methadone: a personalised approach towards optimizing dose
by: Mohamad, Nasir, et al.
Published: (2012)

Effectiveness of Methadone Maintenance Therapy (MMT) and life style improvement among opiate dependent patients registered
by: Christina Malini,, et al.
Published: (2019)

The role of family factors on the relapse behavior of male adolescent opiate abusers in Kerman ( A Province in Iran).
by: Golestan, Samira, et al.
Published: (2010)

A review on Ficus deltoidea medicinal properties and its potential use as ergogenic aids in athletes
by: Yaacob, Azhar, et al.
Published: (2018)

The pyrrolidine ring and its relation with the psychoactivity of mitragynine
by: Mohd Ghazali, Masitah, et al.
Published: (2015)

Investigation Of In Vitro Permeation Of Mitragynine Through The Skin
by: Sim, Yee Shan
Published: (2023)

Synthesis, Characterization And Analgesic Activity Of Mitragynine Analogues
by: Ramlee, Nurul Izzati
Published: (2015)

A review on characterizations and biocompatibility of functionalized carbon nanotubes in drug delivery design
by: Tan, Julia M., et al.
Published: (2014)

Hepatoprotective action of zerumbone against paracetamol induced hepatotoxicity
by: Fakurazi, Sharida, et al.
Published: (2009)

Effects of three different treatment and rehabilitation programs on quality of life of opiate abusers in Kuala Lumpur and Selangor, Malaysia
by: Salleh, Mohd Azizi
Published: (2016)

D-galactose and aluminium chloride induced rat model with cognitive impairments
by: Musa Chiroma, Samaila, et al.
Published: (2018)

Morphological changes and cellular uptake of functionalized graphene oxide loaded with protocatechuic acid and folic acid in hepatocellular carcinoma cancer cell
by: Buskaran, Kalaivani, et al.
Published: (2020)