Methods and compositions for the prevention of opiate tolerance using mitragynine.
The present invention relates to methods and compositions to counter the side effects of analgesic treatments with opioids such as morphine. Provided are novel treatment regimes comprising the administration of mitragynine for the prevention, reversal and/or delay of the progression and/or developme...
| Main Authors: | , , , , |
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| Format: | Patent |
| Language: | English |
| Published: |
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/32077/ |
| _version_ | 1848847117760593920 |
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| author | Fakurazi, Sharida Baharuldin, Mohamad Taufik Hidayat Mohd Moklas, Mohamad Aris Ithnin, Hairuszah Abd Rahman, Shamima |
| author_facet | Fakurazi, Sharida Baharuldin, Mohamad Taufik Hidayat Mohd Moklas, Mohamad Aris Ithnin, Hairuszah Abd Rahman, Shamima |
| author_sort | Fakurazi, Sharida |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The present invention relates to methods and compositions to counter the side effects of analgesic treatments with opioids such as morphine. Provided are novel treatment regimes comprising the administration of mitragynine for the prevention, reversal and/or delay of the progression and/or development of a tolerance of a subject against the pharmaceutical effects of an opiate. Also comprised by the present invention are therapeutic means for the treatment of severe or chronic pain using a combination of mitragynine and opiates, as well as pharmaceutical compositions comprising the compounds of the present invention. |
| first_indexed | 2025-11-15T09:13:31Z |
| format | Patent |
| id | upm-32077 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:13:31Z |
| publishDate | 2011 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-320772014-10-15T07:45:22Z http://psasir.upm.edu.my/id/eprint/32077/ Methods and compositions for the prevention of opiate tolerance using mitragynine. Fakurazi, Sharida Baharuldin, Mohamad Taufik Hidayat Mohd Moklas, Mohamad Aris Ithnin, Hairuszah Abd Rahman, Shamima The present invention relates to methods and compositions to counter the side effects of analgesic treatments with opioids such as morphine. Provided are novel treatment regimes comprising the administration of mitragynine for the prevention, reversal and/or delay of the progression and/or development of a tolerance of a subject against the pharmaceutical effects of an opiate. Also comprised by the present invention are therapeutic means for the treatment of severe or chronic pain using a combination of mitragynine and opiates, as well as pharmaceutical compositions comprising the compounds of the present invention. 2011-01-14 Patent NonPeerReviewed Sharida Fakurazi (2011) Methods and compositions for the prevention of opiate tolerance using mitragynine. PI 2011700001. English |
| spellingShingle | Fakurazi, Sharida Baharuldin, Mohamad Taufik Hidayat Mohd Moklas, Mohamad Aris Ithnin, Hairuszah Abd Rahman, Shamima Methods and compositions for the prevention of opiate tolerance using mitragynine. |
| title | Methods and compositions for the prevention of opiate tolerance using mitragynine. |
| title_full | Methods and compositions for the prevention of opiate tolerance using mitragynine. |
| title_fullStr | Methods and compositions for the prevention of opiate tolerance using mitragynine. |
| title_full_unstemmed | Methods and compositions for the prevention of opiate tolerance using mitragynine. |
| title_short | Methods and compositions for the prevention of opiate tolerance using mitragynine. |
| title_sort | methods and compositions for the prevention of opiate tolerance using mitragynine. |
| url | http://psasir.upm.edu.my/id/eprint/32077/ |