Method for the purification of interferon.
The present invention discloses a method for the purification of a recombinant microbial Interferon α-2b in an aqueous two-phase system comprising a combination polymer and salt solution. In an embodiment of the present invention, the aqueous two-phase system comprising a combination of polymer and...
| Main Authors: | , , , |
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| Format: | Patent |
| Published: |
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/32048/ |
| _version_ | 1848847109559681024 |
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| author | Ling, Tau Chuan Lin, Yu Kiat Ooi, Chien Wei Ariff, Arbakariya |
| author_facet | Ling, Tau Chuan Lin, Yu Kiat Ooi, Chien Wei Ariff, Arbakariya |
| author_sort | Ling, Tau Chuan |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The present invention discloses a method for the purification of a recombinant microbial Interferon α-2b in an aqueous two-phase system comprising a combination polymer and salt solution. In an embodiment of the present invention, the aqueous two-phase system comprising a combination of polymer and salt solution includes polyethylene glycol (PEG)-potassium phosphate, polyethylene glycol (PEG)-ammonium sulfate, polyethylene glycol (PEG)-sodium carbonate, polyethylene glycol (PEG)-sodium citrate and polyethylene glycol (PEG)-magnesium sulfate. The preferred aqueous two-phase system is the polyethylene glycol (PEG)-potassium phosphate system due to the benefits of low cost and short phase separation time as compared to other systems. |
| first_indexed | 2025-11-15T09:13:23Z |
| format | Patent |
| id | upm-32048 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T09:13:23Z |
| publishDate | 2011 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-320482014-09-04T04:38:40Z http://psasir.upm.edu.my/id/eprint/32048/ Method for the purification of interferon. Ling, Tau Chuan Lin, Yu Kiat Ooi, Chien Wei Ariff, Arbakariya The present invention discloses a method for the purification of a recombinant microbial Interferon α-2b in an aqueous two-phase system comprising a combination polymer and salt solution. In an embodiment of the present invention, the aqueous two-phase system comprising a combination of polymer and salt solution includes polyethylene glycol (PEG)-potassium phosphate, polyethylene glycol (PEG)-ammonium sulfate, polyethylene glycol (PEG)-sodium carbonate, polyethylene glycol (PEG)-sodium citrate and polyethylene glycol (PEG)-magnesium sulfate. The preferred aqueous two-phase system is the polyethylene glycol (PEG)-potassium phosphate system due to the benefits of low cost and short phase separation time as compared to other systems. 2011-01-12 Patent NonPeerReviewed Ling Tau Chuan (2011) Method for the purification of interferon. PI2011000150. |
| spellingShingle | Ling, Tau Chuan Lin, Yu Kiat Ooi, Chien Wei Ariff, Arbakariya Method for the purification of interferon. |
| title | Method for the purification of interferon. |
| title_full | Method for the purification of interferon. |
| title_fullStr | Method for the purification of interferon. |
| title_full_unstemmed | Method for the purification of interferon. |
| title_short | Method for the purification of interferon. |
| title_sort | method for the purification of interferon. |
| url | http://psasir.upm.edu.my/id/eprint/32048/ |