A glucosinolate-rich extract of Japanese Daikon perturbs carcinogen-metabolizing enzyme systems in rat, being a potent inducer of hepatic glutathione S-transferase.

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A glucosinolate-rich extract of Japanese Daikon perturbs carcinogen-metabolizing enzyme systems in rat, being a potent inducer of hepatic glutathione S-transferase.

Purpose: Glucosinolates/isothiocyanates are an established class of naturally occurring chemopreventive agents, a principal mechanism of action being to limit the generation of genotoxic metabolites of chemical carcinogens, as a result of modulation of cytochrome P450 and phase II detoxification enz...

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Bibliographic Details
Main Authors:	Abdull Razis, Ahmad Faizal, De Nicola, Gina Rosalinda, Pagnotto, Eleonora, Iori, Renato, Ioannides, Costas
Format:	Article
Language:	English English
Published:	Springer Verlag 2013
Online Access:	http://psasir.upm.edu.my/id/eprint/30433/ http://psasir.upm.edu.my/id/eprint/30433/1/A%20glucosinolate.pdf

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