Vinca alkaloids
Vinca alkaloids are a subset of drugs obtained from the Madagascar periwinkle plant. They are naturally extracted from the pink periwinkle plant, Catharanthus roseus G. Don and have a hypoglycemic as well as cytotoxic effects. They have been used to treat diabetes, high blood pressure and have bee...
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| Format: | Article |
| Language: | English English |
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Medknow Publications
2013
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| Online Access: | http://psasir.upm.edu.my/id/eprint/30358/ http://psasir.upm.edu.my/id/eprint/30358/1/Vinca%20alkaloids.pdf |
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| author | Moudi, Maryam Go, Rusea Yong, Christina Seok Yien Salleh @ Japri, Mohd Nazre |
| author_facet | Moudi, Maryam Go, Rusea Yong, Christina Seok Yien Salleh @ Japri, Mohd Nazre |
| author_sort | Moudi, Maryam |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Vinca alkaloids are a subset of drugs obtained from the
Madagascar periwinkle plant. They are naturally extracted from the pink periwinkle plant, Catharanthus roseus G. Don and have a hypoglycemic as well as cytotoxic effects. They have been used to treat diabetes, high blood pressure and have been used as disinfectants. The vinca alkaloids are also important for being cancer fighters. There are four major vinca alkaloids in clinical use: Vinblastine (VBL), vinorelbine (VRL), vincristine (VCR) and vindesine (VDS). VCR, VBL and VRL have been approved for use in the United States. Vinflunine is also a new synthetic vinca alkaloid, which has been approved in Europe for the treatment
of second‑line transitional cell carcinoma of the urothelium is being developed for other malignancies. Vinca alkaloids are the second‑most‑used class of cancer drugs and will stay among the original cancer therapies. Different researches and studies for new vinca alkaloid applications will be carried out in this regard. |
| first_indexed | 2025-11-15T09:06:09Z |
| format | Article |
| id | upm-30358 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T09:06:09Z |
| publishDate | 2013 |
| publisher | Medknow Publications |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-303582015-10-07T01:58:05Z http://psasir.upm.edu.my/id/eprint/30358/ Vinca alkaloids Moudi, Maryam Go, Rusea Yong, Christina Seok Yien Salleh @ Japri, Mohd Nazre Vinca alkaloids are a subset of drugs obtained from the Madagascar periwinkle plant. They are naturally extracted from the pink periwinkle plant, Catharanthus roseus G. Don and have a hypoglycemic as well as cytotoxic effects. They have been used to treat diabetes, high blood pressure and have been used as disinfectants. The vinca alkaloids are also important for being cancer fighters. There are four major vinca alkaloids in clinical use: Vinblastine (VBL), vinorelbine (VRL), vincristine (VCR) and vindesine (VDS). VCR, VBL and VRL have been approved for use in the United States. Vinflunine is also a new synthetic vinca alkaloid, which has been approved in Europe for the treatment of second‑line transitional cell carcinoma of the urothelium is being developed for other malignancies. Vinca alkaloids are the second‑most‑used class of cancer drugs and will stay among the original cancer therapies. Different researches and studies for new vinca alkaloid applications will be carried out in this regard. Medknow Publications 2013-11 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/30358/1/Vinca%20alkaloids.pdf Moudi, Maryam and Go, Rusea and Yong, Christina Seok Yien and Salleh @ Japri, Mohd Nazre (2013) Vinca alkaloids. International Journal of Preventive Medicine, 4 (11). pp. 1231-1235. ISSN 2008-7802; ESSN: 2008-8213 http://www.ijpm.mui.ac.ir/index.php/ijpm/issue/view/42 English |
| spellingShingle | Moudi, Maryam Go, Rusea Yong, Christina Seok Yien Salleh @ Japri, Mohd Nazre Vinca alkaloids |
| title | Vinca alkaloids |
| title_full | Vinca alkaloids |
| title_fullStr | Vinca alkaloids |
| title_full_unstemmed | Vinca alkaloids |
| title_short | Vinca alkaloids |
| title_sort | vinca alkaloids |
| url | http://psasir.upm.edu.my/id/eprint/30358/ http://psasir.upm.edu.my/id/eprint/30358/ http://psasir.upm.edu.my/id/eprint/30358/1/Vinca%20alkaloids.pdf |