A P212121 polymorph of (+)-clusianone

The title compound, C33H42O4[systematic name: (1S,5S,7R)-3-benzoyl-4-hydroxy-8,8-dimethyl-1,5,7-tris(3-methylbut-2-enyl) bicyclo[3.3.1]nona-3-ene-2,9-dione], has a central bicyclo[3.3.1]nonane-2,4,9- trione surrounded by tetraprenylated and benzoyl groups. The compound was recrystallized several tim...

Full description

Bibliographic Details
Main Authors: Nagalingam, Sree Vaneesa, Wong, Janet Pik Ching, Break, Mohammed Khaled, Mohamed Tahir, Mohamed Ibrahim, Khoo, Teng Jin
Format: Article
Language:English
English
Published: International Union of Crystallography 2013
Online Access:http://psasir.upm.edu.my/id/eprint/30268/
http://psasir.upm.edu.my/id/eprint/30268/1/A%20P212121%20polymorph%20of.pdf
_version_ 1848846629061263360
author Nagalingam, Sree Vaneesa
Wong, Janet Pik Ching
Break, Mohammed Khaled
Mohamed Tahir, Mohamed Ibrahim
Khoo, Teng Jin
author_facet Nagalingam, Sree Vaneesa
Wong, Janet Pik Ching
Break, Mohammed Khaled
Mohamed Tahir, Mohamed Ibrahim
Khoo, Teng Jin
author_sort Nagalingam, Sree Vaneesa
building UPM Institutional Repository
collection Online Access
description The title compound, C33H42O4[systematic name: (1S,5S,7R)-3-benzoyl-4-hydroxy-8,8-dimethyl-1,5,7-tris(3-methylbut-2-enyl) bicyclo[3.3.1]nona-3-ene-2,9-dione], has a central bicyclo[3.3.1]nonane-2,4,9- trione surrounded by tetraprenylated and benzoyl groups. The compound was recrystallized several times in methanol using both a slow evaporation method and with a crystal-seeding technique. This subsequently produced diffraction-quality crystals which crystallize in the orthorhombic space group P212121, in contrast to a previous report of a structure determination in the Pna21 space group [McCandlish et al. (1976). Acta Cryst. B32, 1793-1801]. The title compound has a melting point of 365-366 K, and a specific rotation [α]20value of +51.94°. A strong intramolecular O-H⋯O hydrogen bond is noted. In the crystal, molecules are assembled in the ab plane by weak C-H⋯O interactions.
first_indexed 2025-11-15T09:05:45Z
format Article
id upm-30268
institution Universiti Putra Malaysia
institution_category Local University
language English
English
last_indexed 2025-11-15T09:05:45Z
publishDate 2013
publisher International Union of Crystallography
recordtype eprints
repository_type Digital Repository
spelling upm-302682015-12-07T03:30:42Z http://psasir.upm.edu.my/id/eprint/30268/ A P212121 polymorph of (+)-clusianone Nagalingam, Sree Vaneesa Wong, Janet Pik Ching Break, Mohammed Khaled Mohamed Tahir, Mohamed Ibrahim Khoo, Teng Jin The title compound, C33H42O4[systematic name: (1S,5S,7R)-3-benzoyl-4-hydroxy-8,8-dimethyl-1,5,7-tris(3-methylbut-2-enyl) bicyclo[3.3.1]nona-3-ene-2,9-dione], has a central bicyclo[3.3.1]nonane-2,4,9- trione surrounded by tetraprenylated and benzoyl groups. The compound was recrystallized several times in methanol using both a slow evaporation method and with a crystal-seeding technique. This subsequently produced diffraction-quality crystals which crystallize in the orthorhombic space group P212121, in contrast to a previous report of a structure determination in the Pna21 space group [McCandlish et al. (1976). Acta Cryst. B32, 1793-1801]. The title compound has a melting point of 365-366 K, and a specific rotation [α]20value of +51.94°. A strong intramolecular O-H⋯O hydrogen bond is noted. In the crystal, molecules are assembled in the ab plane by weak C-H⋯O interactions. International Union of Crystallography 2013-12 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/30268/1/A%20P212121%20polymorph%20of.pdf Nagalingam, Sree Vaneesa and Wong, Janet Pik Ching and Break, Mohammed Khaled and Mohamed Tahir, Mohamed Ibrahim and Khoo, Teng Jin (2013) A P212121 polymorph of (+)-clusianone. Acta Crystallographica Section E: Structure Reports Online, 69 (pt.12). o1799-o1800. ISSN 1600-5368 http://journals.iucr.org/e/issues/2013/12/00/tk5270/ 10.1107/S1600536813031036 English
spellingShingle Nagalingam, Sree Vaneesa
Wong, Janet Pik Ching
Break, Mohammed Khaled
Mohamed Tahir, Mohamed Ibrahim
Khoo, Teng Jin
A P212121 polymorph of (+)-clusianone
title A P212121 polymorph of (+)-clusianone
title_full A P212121 polymorph of (+)-clusianone
title_fullStr A P212121 polymorph of (+)-clusianone
title_full_unstemmed A P212121 polymorph of (+)-clusianone
title_short A P212121 polymorph of (+)-clusianone
title_sort p212121 polymorph of (+)-clusianone
url http://psasir.upm.edu.my/id/eprint/30268/
http://psasir.upm.edu.my/id/eprint/30268/
http://psasir.upm.edu.my/id/eprint/30268/
http://psasir.upm.edu.my/id/eprint/30268/1/A%20P212121%20polymorph%20of.pdf