Antileukemic properties of spermacoce species
Antileukemic activity of th extracts and isolated compound from Spermacoce articularis, Spermacoce exilis and Spermacoce latifolia were carried out. All extracts of Spermacoce articularis as well as dichloromethane and ethyl acetate extracts of Spermacoce exilis showed strong activity against HL-60...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
Chemic Publishing Company
2013
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| Online Access: | http://psasir.upm.edu.my/id/eprint/30032/ http://psasir.upm.edu.my/id/eprint/30032/1/Antileukemic%20properties%20of%20spermacoce%20species.pdf |
| _version_ | 1848846563841933312 |
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| author | Sukari, Mohd Aspollah Utami, Rahayu Neoh, Bee Keat Ee, Gwendoline Cheng Lian Jusoh, Shokri Mohd Nor, Siti Mariam Rahmani, Mawardi |
| author_facet | Sukari, Mohd Aspollah Utami, Rahayu Neoh, Bee Keat Ee, Gwendoline Cheng Lian Jusoh, Shokri Mohd Nor, Siti Mariam Rahmani, Mawardi |
| author_sort | Sukari, Mohd Aspollah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Antileukemic activity of th extracts and isolated compound from Spermacoce articularis, Spermacoce exilis and Spermacoce latifolia were carried out. All extracts of Spermacoce articularis as well as dichloromethane and ethyl acetate extracts of Spermacoce exilis showed strong activity against HL-60 cancer cell with IC50 value ranging from 0.4 to 7.2 μg/mL, whereas hexane extract of Spermacoce latifolia gave moderate activity with IC50 value of 13 ± 0.19 μg/mL. Ursolic acid as the major isolated constituent of these plants was found to have strong activity with IC50 of 1.3 ± 0.03 μg/mL against the same cancer cell. |
| first_indexed | 2025-11-15T09:04:42Z |
| format | Article |
| id | upm-30032 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T09:04:42Z |
| publishDate | 2013 |
| publisher | Chemic Publishing Company |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-300322016-02-03T01:34:58Z http://psasir.upm.edu.my/id/eprint/30032/ Antileukemic properties of spermacoce species Sukari, Mohd Aspollah Utami, Rahayu Neoh, Bee Keat Ee, Gwendoline Cheng Lian Jusoh, Shokri Mohd Nor, Siti Mariam Rahmani, Mawardi Antileukemic activity of th extracts and isolated compound from Spermacoce articularis, Spermacoce exilis and Spermacoce latifolia were carried out. All extracts of Spermacoce articularis as well as dichloromethane and ethyl acetate extracts of Spermacoce exilis showed strong activity against HL-60 cancer cell with IC50 value ranging from 0.4 to 7.2 μg/mL, whereas hexane extract of Spermacoce latifolia gave moderate activity with IC50 value of 13 ± 0.19 μg/mL. Ursolic acid as the major isolated constituent of these plants was found to have strong activity with IC50 of 1.3 ± 0.03 μg/mL against the same cancer cell. Chemic Publishing Company 2013 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/30032/1/Antileukemic%20properties%20of%20spermacoce%20species.pdf Sukari, Mohd Aspollah and Utami, Rahayu and Neoh, Bee Keat and Ee, Gwendoline Cheng Lian and Jusoh, Shokri and Mohd Nor, Siti Mariam and Rahmani, Mawardi (2013) Antileukemic properties of spermacoce species. Asian Journal of Chemistry, 25 (8). pp. 4595-4598. ISSN 0970-7077 English |
| spellingShingle | Sukari, Mohd Aspollah Utami, Rahayu Neoh, Bee Keat Ee, Gwendoline Cheng Lian Jusoh, Shokri Mohd Nor, Siti Mariam Rahmani, Mawardi Antileukemic properties of spermacoce species |
| title | Antileukemic properties of spermacoce species |
| title_full | Antileukemic properties of spermacoce species |
| title_fullStr | Antileukemic properties of spermacoce species |
| title_full_unstemmed | Antileukemic properties of spermacoce species |
| title_short | Antileukemic properties of spermacoce species |
| title_sort | antileukemic properties of spermacoce species |
| url | http://psasir.upm.edu.my/id/eprint/30032/ http://psasir.upm.edu.my/id/eprint/30032/1/Antileukemic%20properties%20of%20spermacoce%20species.pdf |