Metabolic responses of acute phase protein, antioxidant and cytokine in Arabian endurance horses.
Changes in serum amyloid A (SAA), glutathione reductase (GR) and interleukin-6 (IL-6) could be responsible for the metabolic disorders and poor performance in Arabian horses during gruelling endurance events. Therefore, this study aims to evaluate the metabolic responses in relation to SAA, GR and I...
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| Format: | Article |
| Language: | English |
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Wageningen Academic Publishers
2013
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| Online Access: | http://psasir.upm.edu.my/id/eprint/29893/ http://psasir.upm.edu.my/id/eprint/29893/1/Metabolic%20responses%20of%20acute%20phase%20protein.pdf |
| _version_ | 1848846525526966272 |
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| author | Adamu, Lawan Mohd Adzahan, Noraniza Abdullah, Rasedee Fateh Mohamed, Bashir Ahmad |
| author_facet | Adamu, Lawan Mohd Adzahan, Noraniza Abdullah, Rasedee Fateh Mohamed, Bashir Ahmad |
| author_sort | Adamu, Lawan |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Changes in serum amyloid A (SAA), glutathione reductase (GR) and interleukin-6 (IL-6) could be responsible for the metabolic disorders and poor performance in Arabian horses during gruelling endurance events. Therefore, this study aims to evaluate the metabolic responses in relation to SAA, GR and IL-6 in Arabian horses during endurance events. After physical examination, the successfully completed (SC) (n=16) and eliminated-from-race (ER) (n=16) endurance horses were identified. The data obtained were analysed using ANOVA and pairwise correlations and the analysis were considered significant at P<0.05. There were significant differences between the SC and ER Arabian horses in haemoglobin (Hb), packed cell volume (PCV), creatine kinase, plasma protein, lactate and monocytes (P<0.0001), IL-6, GR (P<0.0007), SAA (P<0.0068), glucose (P<0.00342), aspartate transaminase (P<0.0049) concentrations. There were significant negative correlations between GR and plasma protein (r=-0.2830; P<0.0299) and GR and SAA (r=-0.2554; P<0.0489). There were significant positive correlations between IL-6 and Hb (r=0.2977; P<0.0220) and positive and not significant correlation between IL-6 and PCV (r=0.2449; P<0.0615). In conclusion, SAA, GR and IL-6 were significantly associated with metabolic crises in Arabian endurance horses. Therefore, SAA, GR and IL-6 could be used to evaluate performance and health status of endurance horses during training and endurance events. |
| first_indexed | 2025-11-15T09:04:06Z |
| format | Article |
| id | upm-29893 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:04:06Z |
| publishDate | 2013 |
| publisher | Wageningen Academic Publishers |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-298932015-09-07T04:02:14Z http://psasir.upm.edu.my/id/eprint/29893/ Metabolic responses of acute phase protein, antioxidant and cytokine in Arabian endurance horses. Adamu, Lawan Mohd Adzahan, Noraniza Abdullah, Rasedee Fateh Mohamed, Bashir Ahmad Changes in serum amyloid A (SAA), glutathione reductase (GR) and interleukin-6 (IL-6) could be responsible for the metabolic disorders and poor performance in Arabian horses during gruelling endurance events. Therefore, this study aims to evaluate the metabolic responses in relation to SAA, GR and IL-6 in Arabian horses during endurance events. After physical examination, the successfully completed (SC) (n=16) and eliminated-from-race (ER) (n=16) endurance horses were identified. The data obtained were analysed using ANOVA and pairwise correlations and the analysis were considered significant at P<0.05. There were significant differences between the SC and ER Arabian horses in haemoglobin (Hb), packed cell volume (PCV), creatine kinase, plasma protein, lactate and monocytes (P<0.0001), IL-6, GR (P<0.0007), SAA (P<0.0068), glucose (P<0.00342), aspartate transaminase (P<0.0049) concentrations. There were significant negative correlations between GR and plasma protein (r=-0.2830; P<0.0299) and GR and SAA (r=-0.2554; P<0.0489). There were significant positive correlations between IL-6 and Hb (r=0.2977; P<0.0220) and positive and not significant correlation between IL-6 and PCV (r=0.2449; P<0.0615). In conclusion, SAA, GR and IL-6 were significantly associated with metabolic crises in Arabian endurance horses. Therefore, SAA, GR and IL-6 could be used to evaluate performance and health status of endurance horses during training and endurance events. Wageningen Academic Publishers 2013-05-17 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/29893/1/Metabolic%20responses%20of%20acute%20phase%20protein.pdf Adamu, Lawan and Mohd Adzahan, Noraniza and Abdullah, Rasedee and Fateh Mohamed, Bashir Ahmad (2013) Metabolic responses of acute phase protein, antioxidant and cytokine in Arabian endurance horses. Comparative Exercise Physiology, 9 (1). pp. 51-57. ISSN 1755-2540; ESSN: 1755-2559 10.3920/CEP13001 |
| spellingShingle | Adamu, Lawan Mohd Adzahan, Noraniza Abdullah, Rasedee Fateh Mohamed, Bashir Ahmad Metabolic responses of acute phase protein, antioxidant and cytokine in Arabian endurance horses. |
| title | Metabolic responses of acute phase protein, antioxidant and cytokine in Arabian endurance horses. |
| title_full | Metabolic responses of acute phase protein, antioxidant and cytokine in Arabian endurance horses. |
| title_fullStr | Metabolic responses of acute phase protein, antioxidant and cytokine in Arabian endurance horses. |
| title_full_unstemmed | Metabolic responses of acute phase protein, antioxidant and cytokine in Arabian endurance horses. |
| title_short | Metabolic responses of acute phase protein, antioxidant and cytokine in Arabian endurance horses. |
| title_sort | metabolic responses of acute phase protein, antioxidant and cytokine in arabian endurance horses. |
| url | http://psasir.upm.edu.my/id/eprint/29893/ http://psasir.upm.edu.my/id/eprint/29893/ http://psasir.upm.edu.my/id/eprint/29893/1/Metabolic%20responses%20of%20acute%20phase%20protein.pdf |