Risk factors for Nipah virus infection among Pteropid bats, Peninsular Malaysia
We conducted cross-sectional and longitudinal studies to determine the distribution of and risk factors for seropositivity to Nipah virus (NiV) among Pteropus vampyrus and P. hypomelanus bats in Peninsular Malaysia. Neutralizing antibodies against NiV were detected at most locations surveyed. We obs...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2013
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| Online Access: | http://psasir.upm.edu.my/id/eprint/29839/ http://psasir.upm.edu.my/id/eprint/29839/1/Risk%20factors%20for%20Nipah%20virus%20infection%20among%20Pteropid%20bats.pdf |
| _version_ | 1848846510677032960 |
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| author | Abd Rahman, Sohayati Hassan, Latiffah Epstein, Jonathan H. C. Mamat, Zaini Mohd Yatim, Aziz Syed Hassan, Sharifah Field, Hume E. Hughes, Tom Westrum, Justin Naim, M. S. Arshad, Siti Suri Jamaluddin, A. Aziz Daszak, Peter |
| author_facet | Abd Rahman, Sohayati Hassan, Latiffah Epstein, Jonathan H. C. Mamat, Zaini Mohd Yatim, Aziz Syed Hassan, Sharifah Field, Hume E. Hughes, Tom Westrum, Justin Naim, M. S. Arshad, Siti Suri Jamaluddin, A. Aziz Daszak, Peter |
| author_sort | Abd Rahman, Sohayati |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | We conducted cross-sectional and longitudinal studies to determine the distribution of and risk factors for seropositivity to Nipah virus (NiV) among Pteropus vampyrus and P. hypomelanus bats in Peninsular Malaysia. Neutralizing antibodies against NiV were detected at most locations surveyed. We observed a consistently higher NiV risk (odds ratio 3.9) and seroprevalence (32.8%) for P. vampyrus than P. hypomelanus (11.1%) bats. A 3-year longitudinal study of P. hypomelanus bats indicated nonseasonal temporal variation in seroprevalence, evidence for viral circulation within the study period, and an overall NiV seroprevalence of 9.8%. The seroprevalence fluctuated over the study duration between 1% and 20% and generally decreased during 2004–2006. Adult bats, particularly pregnant, with dependent pup and lactating bats, had a higher prevalence of NiV antibodies than juveniles. Antibodies in juveniles 6 months–2 years of age suggested viral circulation within the study period. |
| first_indexed | 2025-11-15T09:03:52Z |
| format | Article |
| id | upm-29839 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:03:52Z |
| publishDate | 2013 |
| publisher | Centers for Disease Control and Prevention |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-298392015-09-08T02:11:14Z http://psasir.upm.edu.my/id/eprint/29839/ Risk factors for Nipah virus infection among Pteropid bats, Peninsular Malaysia Abd Rahman, Sohayati Hassan, Latiffah Epstein, Jonathan H. C. Mamat, Zaini Mohd Yatim, Aziz Syed Hassan, Sharifah Field, Hume E. Hughes, Tom Westrum, Justin Naim, M. S. Arshad, Siti Suri Jamaluddin, A. Aziz Daszak, Peter We conducted cross-sectional and longitudinal studies to determine the distribution of and risk factors for seropositivity to Nipah virus (NiV) among Pteropus vampyrus and P. hypomelanus bats in Peninsular Malaysia. Neutralizing antibodies against NiV were detected at most locations surveyed. We observed a consistently higher NiV risk (odds ratio 3.9) and seroprevalence (32.8%) for P. vampyrus than P. hypomelanus (11.1%) bats. A 3-year longitudinal study of P. hypomelanus bats indicated nonseasonal temporal variation in seroprevalence, evidence for viral circulation within the study period, and an overall NiV seroprevalence of 9.8%. The seroprevalence fluctuated over the study duration between 1% and 20% and generally decreased during 2004–2006. Adult bats, particularly pregnant, with dependent pup and lactating bats, had a higher prevalence of NiV antibodies than juveniles. Antibodies in juveniles 6 months–2 years of age suggested viral circulation within the study period. Centers for Disease Control and Prevention 2013-01 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/29839/1/Risk%20factors%20for%20Nipah%20virus%20infection%20among%20Pteropid%20bats.pdf Abd Rahman, Sohayati and Hassan, Latiffah and Epstein, Jonathan H. and C. Mamat, Zaini and Mohd Yatim, Aziz and Syed Hassan, Sharifah and Field, Hume E. and Hughes, Tom and Westrum, Justin and Naim, M. S. and Arshad, Siti Suri and Jamaluddin, A. Aziz and Daszak, Peter (2013) Risk factors for Nipah virus infection among Pteropid bats, Peninsular Malaysia. Emerging Infectious Diseases, 19 (1). pp. 51-60. ISSN 1080-6040; ESSN: 1080-6059 http://wwwnc.cdc.gov/eid/article/19/1/12-0221_article 10.3201/eid1901.120221 |
| spellingShingle | Abd Rahman, Sohayati Hassan, Latiffah Epstein, Jonathan H. C. Mamat, Zaini Mohd Yatim, Aziz Syed Hassan, Sharifah Field, Hume E. Hughes, Tom Westrum, Justin Naim, M. S. Arshad, Siti Suri Jamaluddin, A. Aziz Daszak, Peter Risk factors for Nipah virus infection among Pteropid bats, Peninsular Malaysia |
| title | Risk factors for Nipah virus infection among Pteropid bats, Peninsular Malaysia |
| title_full | Risk factors for Nipah virus infection among Pteropid bats, Peninsular Malaysia |
| title_fullStr | Risk factors for Nipah virus infection among Pteropid bats, Peninsular Malaysia |
| title_full_unstemmed | Risk factors for Nipah virus infection among Pteropid bats, Peninsular Malaysia |
| title_short | Risk factors for Nipah virus infection among Pteropid bats, Peninsular Malaysia |
| title_sort | risk factors for nipah virus infection among pteropid bats, peninsular malaysia |
| url | http://psasir.upm.edu.my/id/eprint/29839/ http://psasir.upm.edu.my/id/eprint/29839/ http://psasir.upm.edu.my/id/eprint/29839/ http://psasir.upm.edu.my/id/eprint/29839/1/Risk%20factors%20for%20Nipah%20virus%20infection%20among%20Pteropid%20bats.pdf |