A plethora of human pluripotent stem cells
At the early stages of mammalian development, a number of developmentally plastic cells appear that possess the ability to give rise to all of the differentiated cell types normally derived from the three primary germ layers - unique character known as pluripotency. To date, embryonic stem cells (ES...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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John Wiley & Sons Ltd.
2013
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| Online Access: | http://psasir.upm.edu.my/id/eprint/29706/ http://psasir.upm.edu.my/id/eprint/29706/1/A%20plethora%20of%20human%20pluripotent%20stem%20cells.pdf |
| _version_ | 1848846473538568192 |
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| author | Liyang, Gao Thilakavathy, Karuppiah Nordin, Norshariza |
| author_facet | Liyang, Gao Thilakavathy, Karuppiah Nordin, Norshariza |
| author_sort | Liyang, Gao |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | At the early stages of mammalian development, a number of developmentally plastic cells appear that possess the ability to give rise to all of the differentiated cell types normally derived from the three primary germ layers - unique character known as pluripotency. To date, embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have been shown to be truly pluripotent. However, recent studies have revealed a variety of other cells that demonstrate pluripotentiality, including very small embryonic-like stem cells (VSELs), amniotic fluid stem cells (AFSCs), marrow-isolated adult multilineage inducible cells (MIAMI) and multipotent adult precursor cells (MAPCs). This review summarises key features of these six kinds of pluripotent and potentially pluripotent stem cells (ESCs, iPSCs, VSELs, AFSCs, MIAMI and MAPCs) and the evidence for their pluripotency properties. |
| first_indexed | 2025-11-15T09:03:16Z |
| format | Article |
| id | upm-29706 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:03:16Z |
| publishDate | 2013 |
| publisher | John Wiley & Sons Ltd. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-297062015-10-01T03:58:43Z http://psasir.upm.edu.my/id/eprint/29706/ A plethora of human pluripotent stem cells Liyang, Gao Thilakavathy, Karuppiah Nordin, Norshariza At the early stages of mammalian development, a number of developmentally plastic cells appear that possess the ability to give rise to all of the differentiated cell types normally derived from the three primary germ layers - unique character known as pluripotency. To date, embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have been shown to be truly pluripotent. However, recent studies have revealed a variety of other cells that demonstrate pluripotentiality, including very small embryonic-like stem cells (VSELs), amniotic fluid stem cells (AFSCs), marrow-isolated adult multilineage inducible cells (MIAMI) and multipotent adult precursor cells (MAPCs). This review summarises key features of these six kinds of pluripotent and potentially pluripotent stem cells (ESCs, iPSCs, VSELs, AFSCs, MIAMI and MAPCs) and the evidence for their pluripotency properties. John Wiley & Sons Ltd. 2013-09 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/29706/1/A%20plethora%20of%20human%20pluripotent%20stem%20cells.pdf Liyang, Gao and Thilakavathy, Karuppiah and Nordin, Norshariza (2013) A plethora of human pluripotent stem cells. Cell Biology International, 37 (9). pp. 875-887. ISSN 1065-6995; E3SSN: 1095-8355 10.1002/cbin.10120 |
| spellingShingle | Liyang, Gao Thilakavathy, Karuppiah Nordin, Norshariza A plethora of human pluripotent stem cells |
| title | A plethora of human pluripotent stem cells |
| title_full | A plethora of human pluripotent stem cells |
| title_fullStr | A plethora of human pluripotent stem cells |
| title_full_unstemmed | A plethora of human pluripotent stem cells |
| title_short | A plethora of human pluripotent stem cells |
| title_sort | plethora of human pluripotent stem cells |
| url | http://psasir.upm.edu.my/id/eprint/29706/ http://psasir.upm.edu.my/id/eprint/29706/ http://psasir.upm.edu.my/id/eprint/29706/1/A%20plethora%20of%20human%20pluripotent%20stem%20cells.pdf |