Bioassay-guided isolation of antifungal plumericin from Allamanda species (Apocynaceae).
Anthracnose is an economically important disease that can cause 10 to 80% yield reduction in the market with its typical symptoms of dark spots, sunken necrotic tissues and concentric rings of acervuli on fruits. One of the important methods to control the disease is by using antifungal agents deri...
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| Format: | Article |
| Language: | English English |
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Asian Network for Scientific Information
2013
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| Online Access: | http://psasir.upm.edu.my/id/eprint/29501/ http://psasir.upm.edu.my/id/eprint/29501/1/Bioassay.pdf |
| _version_ | 1848846415825993728 |
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| author | Haron, Farah Farhanah Sijam, Kamaruzaman Omar, Dzolkhifli Rahmani, Mawardi |
| author_facet | Haron, Farah Farhanah Sijam, Kamaruzaman Omar, Dzolkhifli Rahmani, Mawardi |
| author_sort | Haron, Farah Farhanah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Anthracnose is an economically important disease that can cause 10 to 80% yield reduction in the market with its typical symptoms of dark spots, sunken necrotic tissues and concentric rings of acervuli on fruits. One of the important methods to control the disease is by using antifungal agents derived from plant. Preliminary study indicated that the extracts of Allamanda species have the potential to be developed as the target agent. Five Allamanda species were extracted and screened for antifungal activity against plant pathogenic fungus Colletotrichum gloeosporioides by using poison agar technique. The three chloroform extracts of A. blanchetti, A. cathartica ‘Alba’ and A. cathartica ‘Jamaican Sunset’ exhibited potent inhibitory effects and suppressed the mycelial growth of C. gloeosporioides by up to about 70%. Further study by bioautography-guided fractionation of the extracts led to the isolation and identification of tetracyclic sesquiterpene plumericin as the antifungal agent. The structural determination of the compound was carried out by interpreting the IR, MS, 1D-NMR and 2D-NMR spectral data. |
| first_indexed | 2025-11-15T09:02:21Z |
| format | Article |
| id | upm-29501 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T09:02:21Z |
| publishDate | 2013 |
| publisher | Asian Network for Scientific Information |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-295012015-09-11T00:50:43Z http://psasir.upm.edu.my/id/eprint/29501/ Bioassay-guided isolation of antifungal plumericin from Allamanda species (Apocynaceae). Haron, Farah Farhanah Sijam, Kamaruzaman Omar, Dzolkhifli Rahmani, Mawardi Anthracnose is an economically important disease that can cause 10 to 80% yield reduction in the market with its typical symptoms of dark spots, sunken necrotic tissues and concentric rings of acervuli on fruits. One of the important methods to control the disease is by using antifungal agents derived from plant. Preliminary study indicated that the extracts of Allamanda species have the potential to be developed as the target agent. Five Allamanda species were extracted and screened for antifungal activity against plant pathogenic fungus Colletotrichum gloeosporioides by using poison agar technique. The three chloroform extracts of A. blanchetti, A. cathartica ‘Alba’ and A. cathartica ‘Jamaican Sunset’ exhibited potent inhibitory effects and suppressed the mycelial growth of C. gloeosporioides by up to about 70%. Further study by bioautography-guided fractionation of the extracts led to the isolation and identification of tetracyclic sesquiterpene plumericin as the antifungal agent. The structural determination of the compound was carried out by interpreting the IR, MS, 1D-NMR and 2D-NMR spectral data. Asian Network for Scientific Information 2013 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/29501/1/Bioassay.pdf Haron, Farah Farhanah and Sijam, Kamaruzaman and Omar, Dzolkhifli and Rahmani, Mawardi (2013) Bioassay-guided isolation of antifungal plumericin from Allamanda species (Apocynaceae). Journal of Biological Sciences, 13 (3). pp. 158-162. ISSN 1727-3048; ESSN: 1812-5719 http://scialert.net/archivedetails.php?issn=1727-3048&issueno=107 10.3923/jbs.2013.158.162 English |
| spellingShingle | Haron, Farah Farhanah Sijam, Kamaruzaman Omar, Dzolkhifli Rahmani, Mawardi Bioassay-guided isolation of antifungal plumericin from Allamanda species (Apocynaceae). |
| title | Bioassay-guided isolation of antifungal plumericin from Allamanda species (Apocynaceae). |
| title_full | Bioassay-guided isolation of antifungal plumericin from Allamanda species (Apocynaceae). |
| title_fullStr | Bioassay-guided isolation of antifungal plumericin from Allamanda species (Apocynaceae). |
| title_full_unstemmed | Bioassay-guided isolation of antifungal plumericin from Allamanda species (Apocynaceae). |
| title_short | Bioassay-guided isolation of antifungal plumericin from Allamanda species (Apocynaceae). |
| title_sort | bioassay-guided isolation of antifungal plumericin from allamanda species (apocynaceae). |
| url | http://psasir.upm.edu.my/id/eprint/29501/ http://psasir.upm.edu.my/id/eprint/29501/ http://psasir.upm.edu.my/id/eprint/29501/ http://psasir.upm.edu.my/id/eprint/29501/1/Bioassay.pdf |