Seroprevalence of Toxoplasma gondii among schizophrenics at Hospital Kajang
Studies have found a high seroprevalence of T. gondii in schizophrenia patients than controls. This case-control study was done to determine the serprevalence of Toxoplasma gondii and to identify its risk factors among schizophrenia patients at Hospital Kajang. Eighty-eight (88) schizophrenia patien...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Science Publications
2013
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| Online Access: | http://psasir.upm.edu.my/id/eprint/29459/ http://psasir.upm.edu.my/id/eprint/29459/1/29459.pdf |
| _version_ | 1848846404722622464 |
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| author | Juanah, Lovetta Yatta Jalaludin, Juliana Osman, Malina Jamil @ Osman, Zubaidah |
| author_facet | Juanah, Lovetta Yatta Jalaludin, Juliana Osman, Malina Jamil @ Osman, Zubaidah |
| author_sort | Juanah, Lovetta Yatta |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Studies have found a high seroprevalence of T. gondii in schizophrenia patients than controls. This case-control study was done to determine the serprevalence of Toxoplasma gondii and to identify its risk factors among schizophrenia patients at Hospital Kajang. Eighty-eight (88) schizophrenia patients and 88 non-psychiatric controls were examined for the presence of anti-Toxoplasma IgG and IgM antibodies by Enzyme Linked Immunosorbent Assay (ELISA). Questionnaires were used to collect socio-demographic and behavioral data among the respondents. From the results, the seroprevalence of anti-T. gondii IgG antibodies was significantly higher (51.0%) in schizophrenia patients than in controls (30.7%); (OR = 2.01; 95% CI: 2.16-3.01; p = 0.023. There was no significant association between the socio-demographic factors and toxoplasmosis. Beef consumption (p = 0.004, OR = 3.852, CI: 1.550-9.569), pork consumption (p<0.001, OR = 13.089, 95%CI: 4.730-36.219) and risky cat contact (p = 0.047, OR = 4.061, 95% CI: 1.985-16.745), were found to be significantly associated with T. gondii infection. Our results show that there is a relationship between toxoplasmosis and schizophrenia. |
| first_indexed | 2025-11-15T09:02:11Z |
| format | Article |
| id | upm-29459 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:02:11Z |
| publishDate | 2013 |
| publisher | Science Publications |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-294592016-07-12T09:36:42Z http://psasir.upm.edu.my/id/eprint/29459/ Seroprevalence of Toxoplasma gondii among schizophrenics at Hospital Kajang Juanah, Lovetta Yatta Jalaludin, Juliana Osman, Malina Jamil @ Osman, Zubaidah Studies have found a high seroprevalence of T. gondii in schizophrenia patients than controls. This case-control study was done to determine the serprevalence of Toxoplasma gondii and to identify its risk factors among schizophrenia patients at Hospital Kajang. Eighty-eight (88) schizophrenia patients and 88 non-psychiatric controls were examined for the presence of anti-Toxoplasma IgG and IgM antibodies by Enzyme Linked Immunosorbent Assay (ELISA). Questionnaires were used to collect socio-demographic and behavioral data among the respondents. From the results, the seroprevalence of anti-T. gondii IgG antibodies was significantly higher (51.0%) in schizophrenia patients than in controls (30.7%); (OR = 2.01; 95% CI: 2.16-3.01; p = 0.023. There was no significant association between the socio-demographic factors and toxoplasmosis. Beef consumption (p = 0.004, OR = 3.852, CI: 1.550-9.569), pork consumption (p<0.001, OR = 13.089, 95%CI: 4.730-36.219) and risky cat contact (p = 0.047, OR = 4.061, 95% CI: 1.985-16.745), were found to be significantly associated with T. gondii infection. Our results show that there is a relationship between toxoplasmosis and schizophrenia. Science Publications 2013 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/29459/1/29459.pdf Juanah, Lovetta Yatta and Jalaludin, Juliana and Osman, Malina and Jamil @ Osman, Zubaidah (2013) Seroprevalence of Toxoplasma gondii among schizophrenics at Hospital Kajang. American Journal of Infectious Diseases, 9 (1). pp. 11-16. ISSN 1553-6203; ESSN: 1558-6340 http://thescipub.com/abstract/10.3844/ajidsp.2013.11.16 10.3844/ajidsp.2013.11.16 |
| spellingShingle | Juanah, Lovetta Yatta Jalaludin, Juliana Osman, Malina Jamil @ Osman, Zubaidah Seroprevalence of Toxoplasma gondii among schizophrenics at Hospital Kajang |
| title | Seroprevalence of Toxoplasma gondii among schizophrenics at Hospital Kajang |
| title_full | Seroprevalence of Toxoplasma gondii among schizophrenics at Hospital Kajang |
| title_fullStr | Seroprevalence of Toxoplasma gondii among schizophrenics at Hospital Kajang |
| title_full_unstemmed | Seroprevalence of Toxoplasma gondii among schizophrenics at Hospital Kajang |
| title_short | Seroprevalence of Toxoplasma gondii among schizophrenics at Hospital Kajang |
| title_sort | seroprevalence of toxoplasma gondii among schizophrenics at hospital kajang |
| url | http://psasir.upm.edu.my/id/eprint/29459/ http://psasir.upm.edu.my/id/eprint/29459/ http://psasir.upm.edu.my/id/eprint/29459/ http://psasir.upm.edu.my/id/eprint/29459/1/29459.pdf |