Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds
Plants have been a good source of therapeutic agents for thousands of years; an impressive number of modern drugs used for treating human diseases are derived from natural sources. The Theobroma cacao tree, or cocoa, has recently garnered increasing attention and become the subject of research due t...
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| Format: | Article |
| Language: | English |
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Penerbit Universiti Sains Malaysia
2016
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| Online Access: | http://psasir.upm.edu.my/id/eprint/29166/ http://psasir.upm.edu.my/id/eprint/29166/1/Theobroma%20cacao%20review%20of%20the%20extraction%2C%20isolation%2C%20and%20bioassay%20of%20its%20potential%20anti-cancer%20compounds.pdf |
| _version_ | 1848846323658260480 |
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| author | Baharum, Zainal Md. Akim, Abdah Yap, Taufiq Yun Hin Abd Hamid @ Abdul Razak, Roslida Kasran, Rosmin |
| author_facet | Baharum, Zainal Md. Akim, Abdah Yap, Taufiq Yun Hin Abd Hamid @ Abdul Razak, Roslida Kasran, Rosmin |
| author_sort | Baharum, Zainal |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Plants have been a good source of therapeutic agents for thousands of years; an impressive number of modern drugs used for treating human diseases are derived from natural sources. The Theobroma cacao tree, or cocoa, has recently garnered increasing attention and become the subject of research due to its antioxidant properties, which are related to potential anti-cancer effects. In the past few years, identifying and developing active compounds or extracts from the cocoa bean that might exert anti-cancer effects have become an important area of health- and biomedicine-related research. This review provides an updated overview of T. cacao in terms of its potential anti-cancer compounds and their extraction, in vitro bioassay, purification, and identification. This article also discusses the advantages and disadvantages of the techniques described and reviews the processes for future perspectives of analytical methods from the viewpoint of anti-cancer compound discovery. |
| first_indexed | 2025-11-15T09:00:53Z |
| format | Article |
| id | upm-29166 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:00:53Z |
| publishDate | 2016 |
| publisher | Penerbit Universiti Sains Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-291662016-06-20T06:49:47Z http://psasir.upm.edu.my/id/eprint/29166/ Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds Baharum, Zainal Md. Akim, Abdah Yap, Taufiq Yun Hin Abd Hamid @ Abdul Razak, Roslida Kasran, Rosmin Plants have been a good source of therapeutic agents for thousands of years; an impressive number of modern drugs used for treating human diseases are derived from natural sources. The Theobroma cacao tree, or cocoa, has recently garnered increasing attention and become the subject of research due to its antioxidant properties, which are related to potential anti-cancer effects. In the past few years, identifying and developing active compounds or extracts from the cocoa bean that might exert anti-cancer effects have become an important area of health- and biomedicine-related research. This review provides an updated overview of T. cacao in terms of its potential anti-cancer compounds and their extraction, in vitro bioassay, purification, and identification. This article also discusses the advantages and disadvantages of the techniques described and reviews the processes for future perspectives of analytical methods from the viewpoint of anti-cancer compound discovery. Penerbit Universiti Sains Malaysia 2016 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/29166/1/Theobroma%20cacao%20review%20of%20the%20extraction%2C%20isolation%2C%20and%20bioassay%20of%20its%20potential%20anti-cancer%20compounds.pdf Baharum, Zainal and Md. Akim, Abdah and Yap, Taufiq Yun Hin and Abd Hamid @ Abdul Razak, Roslida and Kasran, Rosmin (2016) Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds. Tropical Life Sciences Research, 27 (1). pp. 21-42. ISSN 1985-3718; ESSN: 2180-4249 http://www.tlsr.usm.my/current.html |
| spellingShingle | Baharum, Zainal Md. Akim, Abdah Yap, Taufiq Yun Hin Abd Hamid @ Abdul Razak, Roslida Kasran, Rosmin Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds |
| title | Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds |
| title_full | Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds |
| title_fullStr | Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds |
| title_full_unstemmed | Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds |
| title_short | Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds |
| title_sort | theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds |
| url | http://psasir.upm.edu.my/id/eprint/29166/ http://psasir.upm.edu.my/id/eprint/29166/ http://psasir.upm.edu.my/id/eprint/29166/1/Theobroma%20cacao%20review%20of%20the%20extraction%2C%20isolation%2C%20and%20bioassay%20of%20its%20potential%20anti-cancer%20compounds.pdf |