Study of the influence of normal and high blood pressure on normal and stenosed carotid bifurcation using fluid-structure interaction

Atherosclerosis (stenosis) is a common cardiovascular disease in which the blood vessel restructures by narrowing, thickening and gets hardened due to the deposition of plaque. A detailed study of narrowing of arteries applying computational aspects which leads to better findings in order to know th...

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Main Authors: Abdul Khader, Shah Mohammed A., Ayachit, Anurag, Pai, Raghuvir, Zubair, Mohammed, Ahmad, Kamarul Arifin, Rao, Vedularajanikanth
Format: Article
Language:English
Published: Trans Tech Publications 2013
Online Access:http://psasir.upm.edu.my/id/eprint/28676/
http://psasir.upm.edu.my/id/eprint/28676/1/Study%20of%20the%20influence%20of%20normal%20and%20high%20blood%20pressure%20on%20normal%20and%20stenosed%20carotid%20bifurcation%20using%20fluid.pdf
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author Abdul Khader, Shah Mohammed A.
Ayachit, Anurag
Pai, Raghuvir
Zubair, Mohammed
Ahmad, Kamarul Arifin
Rao, Vedularajanikanth
author_facet Abdul Khader, Shah Mohammed A.
Ayachit, Anurag
Pai, Raghuvir
Zubair, Mohammed
Ahmad, Kamarul Arifin
Rao, Vedularajanikanth
author_sort Abdul Khader, Shah Mohammed A.
building UPM Institutional Repository
collection Online Access
description Atherosclerosis (stenosis) is a common cardiovascular disease in which the blood vessel restructures by narrowing, thickening and gets hardened due to the deposition of plaque. A detailed study of narrowing of arteries applying computational aspects which leads to better findings in order to know the underlying mechanics of development and progression of such diseases. Such kind of analysis can be a useful tool for the medical professionals to study the realistic physiological conditions. They can simulate and observe the blood flow in arteries. In the present study, a case of normal and stenosed carotid bifurcation is simulated. The models are generated in CATIA based on the clinical data obtained from a patient using Ultrasound Doppler. A transient FSI analysis considering Newtonian behavior is performed to compare the significance of High Blood Pressure (HBP) and Normal Blood Pressure (NBP) on carotid bifurcation. The FSI simulation is carried out for both HBP and NBP conditions for several pulse cycles on normal and stenosed models using ANSYS13.0 to demonstrate the changes in flow behavior at various sections of the model. The computed results agree well with clinical observations and available literature as seen in case of NBP.
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spelling upm-286762015-10-23T02:48:52Z http://psasir.upm.edu.my/id/eprint/28676/ Study of the influence of normal and high blood pressure on normal and stenosed carotid bifurcation using fluid-structure interaction Abdul Khader, Shah Mohammed A. Ayachit, Anurag Pai, Raghuvir Zubair, Mohammed Ahmad, Kamarul Arifin Rao, Vedularajanikanth Atherosclerosis (stenosis) is a common cardiovascular disease in which the blood vessel restructures by narrowing, thickening and gets hardened due to the deposition of plaque. A detailed study of narrowing of arteries applying computational aspects which leads to better findings in order to know the underlying mechanics of development and progression of such diseases. Such kind of analysis can be a useful tool for the medical professionals to study the realistic physiological conditions. They can simulate and observe the blood flow in arteries. In the present study, a case of normal and stenosed carotid bifurcation is simulated. The models are generated in CATIA based on the clinical data obtained from a patient using Ultrasound Doppler. A transient FSI analysis considering Newtonian behavior is performed to compare the significance of High Blood Pressure (HBP) and Normal Blood Pressure (NBP) on carotid bifurcation. The FSI simulation is carried out for both HBP and NBP conditions for several pulse cycles on normal and stenosed models using ANSYS13.0 to demonstrate the changes in flow behavior at various sections of the model. The computed results agree well with clinical observations and available literature as seen in case of NBP. Trans Tech Publications 2013 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/28676/1/Study%20of%20the%20influence%20of%20normal%20and%20high%20blood%20pressure%20on%20normal%20and%20stenosed%20carotid%20bifurcation%20using%20fluid.pdf Abdul Khader, Shah Mohammed A. and Ayachit, Anurag and Pai, Raghuvir and Zubair, Mohammed and Ahmad, Kamarul Arifin and Rao, Vedularajanikanth (2013) Study of the influence of normal and high blood pressure on normal and stenosed carotid bifurcation using fluid-structure interaction. Applied Mechanics and Materials, 315. pp. 982-986. ISSN 1660-9336; ESSN: 1662-7482 http://www.scientific.net/AMM.315.982 10.4028/www.scientific.net/AMM.315.982
spellingShingle Abdul Khader, Shah Mohammed A.
Ayachit, Anurag
Pai, Raghuvir
Zubair, Mohammed
Ahmad, Kamarul Arifin
Rao, Vedularajanikanth
Study of the influence of normal and high blood pressure on normal and stenosed carotid bifurcation using fluid-structure interaction
title Study of the influence of normal and high blood pressure on normal and stenosed carotid bifurcation using fluid-structure interaction
title_full Study of the influence of normal and high blood pressure on normal and stenosed carotid bifurcation using fluid-structure interaction
title_fullStr Study of the influence of normal and high blood pressure on normal and stenosed carotid bifurcation using fluid-structure interaction
title_full_unstemmed Study of the influence of normal and high blood pressure on normal and stenosed carotid bifurcation using fluid-structure interaction
title_short Study of the influence of normal and high blood pressure on normal and stenosed carotid bifurcation using fluid-structure interaction
title_sort study of the influence of normal and high blood pressure on normal and stenosed carotid bifurcation using fluid-structure interaction
url http://psasir.upm.edu.my/id/eprint/28676/
http://psasir.upm.edu.my/id/eprint/28676/
http://psasir.upm.edu.my/id/eprint/28676/
http://psasir.upm.edu.my/id/eprint/28676/1/Study%20of%20the%20influence%20of%20normal%20and%20high%20blood%20pressure%20on%20normal%20and%20stenosed%20carotid%20bifurcation%20using%20fluid.pdf