Effects of medium and culture conditions on folate production by Streptococcus thermophilus BAA-250.

The present study was conducted to investigate the effects of culture conditions on folate production by Streptococcus thermophilus BAA-250. Lactose (3g/L) and yeast extract (20g/L) were found to be the more suitable carbon and nitrogen sources for folate production by S. thermophilus BAA-250....

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Main Authors: Mousavi, Seyed Sadegh, Moeini, Hassan, Mohamad, Rosfarizan, Dinarvand, Mojdeh, Ariff, Arbakariya, Foo, Hooi Ling, Abdul Rahim, Raha
Format: Article
Language:English
English
Published: 2013
Online Access:http://psasir.upm.edu.my/id/eprint/28123/
http://psasir.upm.edu.my/id/eprint/28123/1/Effects%20of%20medium%20and%20culture%20conditions%20on%20folate%20production%20by%20Streptococcus%20thermophilus%20BAA.pdf
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author Mousavi, Seyed Sadegh
Moeini, Hassan
Mohamad, Rosfarizan
Dinarvand, Mojdeh
Ariff, Arbakariya
Foo, Hooi Ling
Abdul Rahim, Raha
author_facet Mousavi, Seyed Sadegh
Moeini, Hassan
Mohamad, Rosfarizan
Dinarvand, Mojdeh
Ariff, Arbakariya
Foo, Hooi Ling
Abdul Rahim, Raha
author_sort Mousavi, Seyed Sadegh
building UPM Institutional Repository
collection Online Access
description The present study was conducted to investigate the effects of culture conditions on folate production by Streptococcus thermophilus BAA-250. Lactose (3g/L) and yeast extract (20g/L) were found to be the more suitable carbon and nitrogen sources for folate production by S. thermophilus BAA-250. para-aminobenzoic acid (pABA) higher than 1 µM had no significant effect on folate biosynthesis. The optimum pH for folate production was shown to be 7.0 with a folate yield and productivity of 54.53 (µg/L) and 2.27 (µg/L.h), respectively. Optimum folate production obtained in the presence of lactose and yeast extract in a controlled pH of 7 during batch fermentation in bioreactor. Kinetic studies indicated that folate production by S. thermophilus is growth-associated process.
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institution Universiti Putra Malaysia
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language English
English
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publishDate 2013
recordtype eprints
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spelling upm-281232015-10-08T01:22:19Z http://psasir.upm.edu.my/id/eprint/28123/ Effects of medium and culture conditions on folate production by Streptococcus thermophilus BAA-250. Mousavi, Seyed Sadegh Moeini, Hassan Mohamad, Rosfarizan Dinarvand, Mojdeh Ariff, Arbakariya Foo, Hooi Ling Abdul Rahim, Raha The present study was conducted to investigate the effects of culture conditions on folate production by Streptococcus thermophilus BAA-250. Lactose (3g/L) and yeast extract (20g/L) were found to be the more suitable carbon and nitrogen sources for folate production by S. thermophilus BAA-250. para-aminobenzoic acid (pABA) higher than 1 µM had no significant effect on folate biosynthesis. The optimum pH for folate production was shown to be 7.0 with a folate yield and productivity of 54.53 (µg/L) and 2.27 (µg/L.h), respectively. Optimum folate production obtained in the presence of lactose and yeast extract in a controlled pH of 7 during batch fermentation in bioreactor. Kinetic studies indicated that folate production by S. thermophilus is growth-associated process. 2013 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/28123/1/Effects%20of%20medium%20and%20culture%20conditions%20on%20folate%20production%20by%20Streptococcus%20thermophilus%20BAA.pdf Mousavi, Seyed Sadegh and Moeini, Hassan and Mohamad, Rosfarizan and Dinarvand, Mojdeh and Ariff, Arbakariya and Foo, Hooi Ling and Abdul Rahim, Raha (2013) Effects of medium and culture conditions on folate production by Streptococcus thermophilus BAA-250. Research in Biotechnology, 4 (6). pp. 21-29. ISSN 2229-791X http://researchinbiotechnology.com/issue/view/21 English
spellingShingle Mousavi, Seyed Sadegh
Moeini, Hassan
Mohamad, Rosfarizan
Dinarvand, Mojdeh
Ariff, Arbakariya
Foo, Hooi Ling
Abdul Rahim, Raha
Effects of medium and culture conditions on folate production by Streptococcus thermophilus BAA-250.
title Effects of medium and culture conditions on folate production by Streptococcus thermophilus BAA-250.
title_full Effects of medium and culture conditions on folate production by Streptococcus thermophilus BAA-250.
title_fullStr Effects of medium and culture conditions on folate production by Streptococcus thermophilus BAA-250.
title_full_unstemmed Effects of medium and culture conditions on folate production by Streptococcus thermophilus BAA-250.
title_short Effects of medium and culture conditions on folate production by Streptococcus thermophilus BAA-250.
title_sort effects of medium and culture conditions on folate production by streptococcus thermophilus baa-250.
url http://psasir.upm.edu.my/id/eprint/28123/
http://psasir.upm.edu.my/id/eprint/28123/
http://psasir.upm.edu.my/id/eprint/28123/1/Effects%20of%20medium%20and%20culture%20conditions%20on%20folate%20production%20by%20Streptococcus%20thermophilus%20BAA.pdf