Ligand-based virtual screening for the discovery of inhibitors for protein arginine deiminase type 4 (PAD4)

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Ligand-based virtual screening for the discovery of inhibitors for protein arginine deiminase type 4 (PAD4)

Protein Arginine Deiminase type 4 (PAD4) is a new therapeutic target for the treatment of rheumatoid arthritis. In this study, ligand-based virtual screening with the integration with drug repurposing strategy was applied to the discovery of PAD4 inhibitors. Ultrafast Shape Recognition (USR) was use...

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Bibliographic Details
Main Authors:	Teo, Chian Ying, Abdul Rahman, Mohd Basyaruddin, Leow, Adam Thean Chor, Salleh, Abu Bakar, Ballester, Pedro J., Tejo, Bimo Ario
Format:	Article
Language:	English
Published:	OMICS International 2013
Online Access:	http://psasir.upm.edu.my/id/eprint/28103/ http://psasir.upm.edu.my/id/eprint/28103/1/ligandbased-virtual-screening-for-the-discovery-of-inhibitors-for-protein-arginine-deiminase-type-pad-2153-0769-3-118.pdf

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