An integrated bioreactor-expanded bed adsorption system for the removal of acetate to enhance the production of alpha-interferon-2b by Escherichia coli
A stirred tank bioreactor (STB) integrated with an expanded bed adsorption (EBA) system containing anion-exchange resin (Diaion WA30) was developed for in situ removal of acetate to increase the production of α-interferon-2b (α-PrIFN-2b) by Escherichia coli (E. coli). Although the total acetate (9.7...
| Main Authors: | Tan, Joo Shun, Ling, Tau Chuan, Mustafa, Shuhaimi, Tam, Yew Joon, Ramanan, Ramakrishnan Nagasundara, Ariff, Arbakariya |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2013
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/28066/ http://psasir.upm.edu.my/id/eprint/28066/1/An%20integrated%20bioreactor-expanded%20bed%20adsorption%20system%20for%20the%20removal%20of%20acetate%20to%20enhance%20the%20production%20of%20alpha-interferon-2b%20by%20Escherichia%20coli.pdf |
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