Synthesis and anti-microbial potencies of 1-(2-hydroxyethyl)-3-alkylimidazolium chloride ionic liquids: microbial viabilities at different ionic liquids concentrations

Three 1-(2-hydroxyethyl)-3-alkylimidazolium chloride room temperature ionic liquids (ILs) [2OHimCn][Cl]; (n=0, 1, 4) have been synthesized from the appropriate imidazole precursors and characterized by IR and NMR spectroscopies and elemental analysis. Their anti-microbial activities were investigate...

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Main Authors: Hossain, Mohammad Ismail, El-Harbawi, Mohanad, Mohammed Alitheen, Noorjahan Banu, Noaman, Yousr Abdulhadi, Leveque, Jean-Marc, Yin, Chun Yang
Format: Article
Language:English
Published: Elsevier 2013
Online Access:http://psasir.upm.edu.my/id/eprint/28021/
http://psasir.upm.edu.my/id/eprint/28021/1/28021.pdf
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author Hossain, Mohammad Ismail
El-Harbawi, Mohanad
Mohammed Alitheen, Noorjahan Banu
Noaman, Yousr Abdulhadi
Leveque, Jean-Marc
Yin, Chun Yang
author_facet Hossain, Mohammad Ismail
El-Harbawi, Mohanad
Mohammed Alitheen, Noorjahan Banu
Noaman, Yousr Abdulhadi
Leveque, Jean-Marc
Yin, Chun Yang
author_sort Hossain, Mohammad Ismail
building UPM Institutional Repository
collection Online Access
description Three 1-(2-hydroxyethyl)-3-alkylimidazolium chloride room temperature ionic liquids (ILs) [2OHimCn][Cl]; (n=0, 1, 4) have been synthesized from the appropriate imidazole precursors and characterized by IR and NMR spectroscopies and elemental analysis. Their anti-microbial activities were investigated using the well-diffusion method. The viabilities of Escherichia coli, Aeromonas hydrophila, Listeria monocytogenes and Salmonella enterica as a function of IL concentrations were studied. The minimal inhibitory concentrations (MICs) and EC50 values for the present ILs were within the concentration range from 60 to 125 mM and 23 to 73 mM. The anti-microbial potencies of the present ILs were compared to a standard antibiotic, gentamicin. The finding affords additional perspective on the level of ILs toxicity to aquatic lifeforms and yet, this characteristic can be readily harnessed to detect microbial growth and activity.
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publishDate 2013
publisher Elsevier
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spelling upm-280212016-03-07T06:57:56Z http://psasir.upm.edu.my/id/eprint/28021/ Synthesis and anti-microbial potencies of 1-(2-hydroxyethyl)-3-alkylimidazolium chloride ionic liquids: microbial viabilities at different ionic liquids concentrations Hossain, Mohammad Ismail El-Harbawi, Mohanad Mohammed Alitheen, Noorjahan Banu Noaman, Yousr Abdulhadi Leveque, Jean-Marc Yin, Chun Yang Three 1-(2-hydroxyethyl)-3-alkylimidazolium chloride room temperature ionic liquids (ILs) [2OHimCn][Cl]; (n=0, 1, 4) have been synthesized from the appropriate imidazole precursors and characterized by IR and NMR spectroscopies and elemental analysis. Their anti-microbial activities were investigated using the well-diffusion method. The viabilities of Escherichia coli, Aeromonas hydrophila, Listeria monocytogenes and Salmonella enterica as a function of IL concentrations were studied. The minimal inhibitory concentrations (MICs) and EC50 values for the present ILs were within the concentration range from 60 to 125 mM and 23 to 73 mM. The anti-microbial potencies of the present ILs were compared to a standard antibiotic, gentamicin. The finding affords additional perspective on the level of ILs toxicity to aquatic lifeforms and yet, this characteristic can be readily harnessed to detect microbial growth and activity. Elsevier 2013-01-01 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/28021/1/28021.pdf Hossain, Mohammad Ismail and El-Harbawi, Mohanad and Mohammed Alitheen, Noorjahan Banu and Noaman, Yousr Abdulhadi and Leveque, Jean-Marc and Yin, Chun Yang (2013) Synthesis and anti-microbial potencies of 1-(2-hydroxyethyl)-3-alkylimidazolium chloride ionic liquids: microbial viabilities at different ionic liquids concentrations. Ecotoxicology and Environmental Safety, 87. pp. 65-69. ISSN 0147-6513; ESSN: 1090-2414 10.1016/j.ecoenv.2012.09.020
spellingShingle Hossain, Mohammad Ismail
El-Harbawi, Mohanad
Mohammed Alitheen, Noorjahan Banu
Noaman, Yousr Abdulhadi
Leveque, Jean-Marc
Yin, Chun Yang
Synthesis and anti-microbial potencies of 1-(2-hydroxyethyl)-3-alkylimidazolium chloride ionic liquids: microbial viabilities at different ionic liquids concentrations
title Synthesis and anti-microbial potencies of 1-(2-hydroxyethyl)-3-alkylimidazolium chloride ionic liquids: microbial viabilities at different ionic liquids concentrations
title_full Synthesis and anti-microbial potencies of 1-(2-hydroxyethyl)-3-alkylimidazolium chloride ionic liquids: microbial viabilities at different ionic liquids concentrations
title_fullStr Synthesis and anti-microbial potencies of 1-(2-hydroxyethyl)-3-alkylimidazolium chloride ionic liquids: microbial viabilities at different ionic liquids concentrations
title_full_unstemmed Synthesis and anti-microbial potencies of 1-(2-hydroxyethyl)-3-alkylimidazolium chloride ionic liquids: microbial viabilities at different ionic liquids concentrations
title_short Synthesis and anti-microbial potencies of 1-(2-hydroxyethyl)-3-alkylimidazolium chloride ionic liquids: microbial viabilities at different ionic liquids concentrations
title_sort synthesis and anti-microbial potencies of 1-(2-hydroxyethyl)-3-alkylimidazolium chloride ionic liquids: microbial viabilities at different ionic liquids concentrations
url http://psasir.upm.edu.my/id/eprint/28021/
http://psasir.upm.edu.my/id/eprint/28021/
http://psasir.upm.edu.my/id/eprint/28021/1/28021.pdf